Emphysema
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Biomarkers and Genetic Factors Related to Emphysema
This completed clinical trial investigated biomarkers and genetic factors associated with emphysema, a form of chronic obstructive pulmonary…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability [NA]
This completed clinical trial evaluated ex-vivo perfusion and ventilation of donor lungs recovered from non-heart-beating donors to assess t…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema [NA]
Clinical trial update on the safety and effectiveness of the IBV Valve System for the treatment of severe emphysema; the study has completed…
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis [Phase 4]
A Phase 4 clinical trial update evaluating the effectiveness of roflumilast in improving mucociliary clearance in patients with COPD and chr…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study [NA]
Clinical trial update for the RENEW study of lung volume reduction coil treatment in emphysema; the study is terminated with results posted …
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Study Comparing Simulect Plus Standard Immunosuppression to Standard Immunosuppression Alone for the Prevention of Acute Rejection and Bronchiolitis Obliterans in Lung Transplant [Phase 3]
Phase 3 randomized trial comparing Simulect (basiliximab) plus standard immunosuppression to standard immunosuppression alone for prevention…
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Efficacy of Losartan in Preventing Progression of COPD [Phase 4]
Phase 4 clinical trial update reporting the completion and posted results of evaluating losartan for preventing progression of chronic obstr…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Electrical Impedance Imaging of Patients on Mechanical Ventilation
Completed clinical trial evaluating electrical impedance imaging in mechanically ventilated patients to characterize chest conditions such a…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: TESRA: (Treatment of Emphysema With a Gamma-Selective Retinoid Agonist) [Phase 2]
Phase 2 TESRA trial evaluating a gamma-selective retinoid agonist for emphysema has completed.
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency. [Phase 4]
This is a Phase 4 extension study of intravenous Zemaira in subjects with emphysema due to alpha-1 antitrypsin deficiency; results from the …
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Emphysema: Physiologic Effects of Nutritional Support [Phase 2]
Phase 2 trial update assessing the physiologic effects of nutritional support in emphysema.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Medication Adherence in COPD--A Self-Regulation Study
A completed NHLBI-funded clinical trial studying how self-regulation strategies affect medication adherence in chronic obstructive pulmonary…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Blood, Hair and Lung Concentrations of Metals and Metalloids in Patients With Lung Cancer or Chronic Obstructive Pulmonary Disease [NA]
A completed clinical trial update reporting on blood, hair, and lung concentrations of metals and metalloids in patients with lung cancer or…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Evaluation of the Lungs of Individuals With Lung Disease
A completed clinical trial evaluating lung function in individuals with various lung diseases including bronchitis, emphysema, COPD, and ast…
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Alpha1-antitrypsin Deficiency Registry
A completed NHLBI-sponsored clinical trial registry update for Alpha-1 antitrypsin deficiency and related lung diseases such as emphysema an…
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Tucson Epidemiology Study of Chronic Obstructive Lung Diseases
The Tucson Epidemiology Study of Chronic Obstructive Lung Diseases, sponsored by NHLBI, is a completed trial evaluating asthma, bronchitis, …
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CLINICAL_TRIALS trial_result · 2015-10-29Clinical Trial Update: Sequential Segmental Treatment of Emphysema With Upper Lobe Predominance (STEP-UP) Study [NA]
The STEP-UP clinical trial evaluating sequential segmental treatment for emphysema with upper-lobe predominance has completed.
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Single-Breath Measurement Underestimates Ventilatory Volume According to Emphysema Severity
The study reports that single-breath measurements underestimate ventilatory volume in emphysema patients. The extent of underestimation vari…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: ELVR in PH Patients With Severe Emphysema
This entry notes the completion of a clinical trial evaluating endoscopic lung volume reduction (ELVR) in patients with pulmonary hypertensi…
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: A 4 Week Study to Investigate the Safety and Tolerability of AZD5069 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) [Phase 2]
Phase 2 study completed evaluating the safety and tolerability of AZD5069 in patients with moderate-to-severe chronic obstructive pulmonary …
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CLINICAL_TRIALS trial_result · 2015-04-07Clinical Trial Update: Cost-Effectiveness of Lung Volume Reduction Surgery [Phase 2]
A Phase 2 trial evaluating the cost-effectiveness of lung volume reduction surgery in chronic obstructive pulmonary disease and emphysema, w…
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CLINICAL_TRIALS trial_result · 2015-01-19Clinical Trial Update: Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency [Phase 4]
Phase 4 clinical trial update reporting Zemaira (alpha-1 proteinase inhibitor) results in subjects with emphysema due to alpha-1 antitrypsin…
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CLINICAL_TRIALS trial_result · 2014-12-10Clinical Trial Update: Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Emphysema
The clinical trial evaluating rehabilitation for patients with chronic obstructive pulmonary disease and emphysema has completed.
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CLINICAL_TRIALS trial_result · 2014-11-11Clinical Trial Update: Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD) [NA]
A completed clinical trial focused on improving end-of-life communication for patients with COPD, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Imaging Lung Function Using Oxygen Enhanced MRI [Phase 1]
Phase 1 trial update evaluating oxygen-enhanced MRI to image lung function; the study status is completed and encompasses COPD, asthma, and …