Dystonia
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: The Development of a System for Measurement of Tremor [NA]
Completed clinical trial on a system designed to measure tremor in patients with Essential Tremor and Dystonia.
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CLINICAL_TRIALS other · 2025-04-13Clinical Trial Update: The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy [NA]
This entry notes a UCSF-led clinical trial focused on the motor network in Parkinson's disease and dystonia. The status is active but not re…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals [Phase 1]
A Phase 1 single- and multiple-ascending-dose study of MTR-601 in healthy individuals has completed, assessing safety and pharmacokinetics a…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: İnvestigating Dysphagia in Pediatric Dystonia
ClinicalTrials.gov update indicates a pediatric dystonia study sponsored by Gazi University is currently active but not recruiting and is in…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects [NA]
This clinical trial is studying focused ultrasound pallidotomy for dyskinetic cerebral palsy in pediatric and young adult participants; recr…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover Trial [NA]
This clinical trial update describes a prospective, randomized, double-blind crossover study evaluating image-based programming of deep brai…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders [NA]
This entry provides an update on a clinical trial evaluating CUE1 and CUE1+ in people with Parkinson's disease and related disorders; recrui…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: A Post-Market Study Evaluating the Safety of Infinity DBS System With MR Conditional Labeling
A post-market study evaluating the safety of the Infinity DBS System with MR conditional labeling has completed, with results posted.
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Register for Patients With Thyroid Hormone Resistance.
Charite University, Berlin, is recruiting participants for a clinical trial addressing thyroid hormone resistance, including Allan-Herndon-D…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Efficacy and Safety of DBS in Patients With Primary Dystonia [NA]
This completed clinical trial evaluated the efficacy and safety of deep brain stimulation in patients with dystonia.
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: An Open-label Study to Define the Safety, Tolerability and Clinical Activity of Deutetrabenazine (AUstedo) in Adult Study Subjects With DYsTonia [Phase 1, Phase 2]
An open-label Phase 1/2 study in adults with primary dystonia evaluated the safety, tolerability, and clinical activity of Austedo (deutetra…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Validation of a Quality of Life Assessment Tool in Adult Generalized Dystonodyskinetic Syndromes Treated by Continuous Electrical Neuromodulation [NA]
Clinical trial update describing validation of a quality-of-life assessment tool for adults with generalized dystonodyskinetic syndromes tre…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
Completed database study aggregating clinical data from individuals with IRF2BPL gene variants. Observed conditions include Autism Spectrum …
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery
This ongoing clinical study uses microelectrode recording during deep brain stimulation surgery to measure sensory gating and explore neural…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Harmonic Ratio in Patients With GLUT1 Deficiency Syndrome
This clinical trial update indicates the Harmonic Ratio study in GLUT1 deficiency syndrome is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Strategy to Adapt Botulinum Toxin Doses in Dystonia
This clinical trial update discusses strategies for adapting botulinum toxin dosing in dystonia. It outlines study design considerations and…
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: rTMS and Botulinum Toxin in Primary Cervical Dystonia [NA]
Clinical trial update regarding rTMS and botulinum toxin in primary cervical dystonia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation (rTMS) for Dystonia and Tremor [NA]
A completed clinical trial evaluating repetitive transcranial magnetic stimulation (rTMS) for dystonia and tremor with results posted in 202…
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FDA approval · 2023-07-03FDA Approved: BENZTROPINE MESYLATE — Supplemental Application (Fresenius Kabi USA, LLC)
The FDA approved a supplemental application for benztropine mesylate, submitted by Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand [Phase 2]
Phase 2 trial evaluating incobotulinum toxin A (Xeomin) for focal task-specific dystonia of the musician's hand has completed, with results …
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: A Randomized Controlled Trail Comparing Subthalamic and Pallidal Deep Brain Stimulation for Dystonia [Phase 4]
A Phase 4 randomized trial compares subthalamic versus pallidal deep brain stimulation for dystonia and has completed.
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CLINICAL_TRIALS research · 2022-11-10Clinical Trial Update: Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology [NA]
A completed clinical trial evaluating directional deep brain stimulation technology for dystonia in Parkinson's disease patients; results po…
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CLINICAL_TRIALS trial_result · 2022-05-17Clinical Trial Update: Botulinum Toxin Type A for Foot Dystonia-associated Pain in Parkinson's Disease [Phase 2, Phase 3]
Clinical trial update on botulinum toxin type A for foot dystonia-associated pain in Parkinson's disease across Phase 2 and Phase 3.
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FDA approval · 2021-10-14FDA Approved: BENZTROPINE MESYLATE — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved the original application for benztropine mesylate (generic) from Hikma Pharmaceuticals USA Inc., for use in treating Parkinsoni…
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults [NA]
A completed clinical trial evaluating thalamic deep brain stimulation for secondary dystonia in children and young adults; results posted in…