Dystonia
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Towards Noninvasive DBS of the Basal Ganglia in Parkinson's Disease Using TUS [NA]
A clinical trial update describing a study on noninvasive deep brain stimulation of the basal ganglia in Parkinson disease using transcrania…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patients With Refractory Hand Tremor. [NA]
A National Taiwan University Hospital-sponsored clinical trial is recruiting patients with Parkinson's disease, essential tremor, and dyston…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Registry and Natural History of Epilepsy-Dyskinesia Syndromes
A Boston Children's Hospital registry study on the registry and natural history of epilepsy-dyskinesia syndromes, currently recruiting.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Physiological Brain Atlas Development
A Vanderbilt University Medical Center-led clinical trial aims to develop a Physiological Brain Atlas and is currently recruiting for condit…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Effects of Exercise on Dystonia Pathophysiology [NA]
A clinical trial evaluating the effects of exercise on dystonia pathophysiology is currently recruiting participants. The study is sponsored…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy [Phase 1]
This clinical trial update describes a Phase 1 study examining how genetic factors influence the metabolism and clinical response to trihexy…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Dystonia Genotype-Phenotype Correlation
This clinical trial update describes ongoing work to characterize genotype-phenotype correlations in dystonia, with the study currently recr…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia [NA]
This clinical trial update describes the use of long-read genome sequencing to improve the molecular diagnosis of dystonia, with the study c…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders
The study is investigating variable phenotypic presentations of rapid-onset dystonia-parkinsonism and other movement disorders. Recruitment …
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders [NA]
Clinical trial update on ExAblate Transcranial MRgFUS for treatment-refractory movement disorders; the study is currently active but not rec…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: The Development of a System for Measurement of Tremor [NA]
Completed clinical trial on a system designed to measure tremor in patients with Essential Tremor and Dystonia.
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: İnvestigating Dysphagia in Pediatric Dystonia
ClinicalTrials.gov update indicates a pediatric dystonia study sponsored by Gazi University is currently active but not recruiting and is in…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover Trial [NA]
This clinical trial update describes a prospective, randomized, double-blind crossover study evaluating image-based programming of deep brai…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders [NA]
This entry provides an update on a clinical trial evaluating CUE1 and CUE1+ in people with Parkinson's disease and related disorders; recrui…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Register for Patients With Thyroid Hormone Resistance.
Charite University, Berlin, is recruiting participants for a clinical trial addressing thyroid hormone resistance, including Allan-Herndon-D…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
Completed database study aggregating clinical data from individuals with IRF2BPL gene variants. Observed conditions include Autism Spectrum …
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery
This ongoing clinical study uses microelectrode recording during deep brain stimulation surgery to measure sensory gating and explore neural…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Harmonic Ratio in Patients With GLUT1 Deficiency Syndrome
This clinical trial update indicates the Harmonic Ratio study in GLUT1 deficiency syndrome is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Strategy to Adapt Botulinum Toxin Doses in Dystonia
This clinical trial update discusses strategies for adapting botulinum toxin dosing in dystonia. It outlines study design considerations and…
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CLINICAL_TRIALS research · 2022-11-10Clinical Trial Update: Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology [NA]
A completed clinical trial evaluating directional deep brain stimulation technology for dystonia in Parkinson's disease patients; results po…
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CLINICAL_TRIALS research · 2018-06-19Clinical Trial Update: DBS in the Treatment of Intractable Movement Disorders [NA]
A clinical trial update on deep brain stimulation for intractable movement disorders, including Parkinson's disease, Essential tremor, and D…
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CLINICAL_TRIALS research · 2018-03-20Clinical Trial Update: Clinical Trial of STN-DBS for Primary Cranial-Cervical Dystonia [NA]
An update on a clinical trial of subthalamic nucleus deep brain stimulation for primary cranial-cervical dystonia, with no current status re…
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CLINICAL_TRIALS research · 2017-10-06Clinical Trial Update: Brain Anatomy in Dystonia
The brain anatomy study comparing individuals with dystonia to healthy controls, sponsored by the NINDS, has been terminated.
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Brain Function in Focal Dystonia
The document reports that a National Institute of Neurological Disorders and Stroke–sponsored study on brain function in individuals with fo…
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CLINICAL_TRIALS research · 2016-09-08Clinical Trial Update: Can Short Latency Afferent Inhibition Give us Clues to Better DYT 1 Dystonia Treatments?
This clinical trial update discusses using short latency afferent inhibition as a potential approach to improve treatments for DYT1 dystonia…