Dry Eye Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Phase 1 Study for Safety and Tolerability of EBI-005 Topically Administered to Eyes of Healthy Adult Subjects [Phase 1]
This Phase 1 trial reports the safety and tolerability of topically applied EBI-005 in healthy adult volunteers in the context of dry eye di…
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CLINICAL_TRIALS trial_result · 2013-05-07Clinical Trial Update: A Phase II, Dose Ranging Study Of CP-690,550 Eye Drops In Patients With Dry Eye Disease [Phase 2]
Pfizer completed a Phase II dose-ranging study of CP-690,550 eye drops for dry eye disease, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-04-19Clinical Trial Update: ESBA105 in Patients With Severe Dry Eye [Phase 2]
Phase 2 study of ESBA105 for severe dry eye disease completed with results posted.
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CLINICAL_TRIALS trial_result · 2013-04-09Clinical Trial Update: A Prospective, Randomized, Placebo and Active Comparator Controlled Study of CP-690,550 in Subjects With Dry Eye. [Phase 1, Phase 2]
Pfizer's JAK inhibitor CP-690,550 (tofacitinib) was studied in a randomized, placebo- and active-controlled Phase 1/2 trial in adults with d…
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CLINICAL_TRIALS trial_result · 2013-04-04Clinical Trial Update: Punctal Plug Study to Determine the Safety and Retention Times of Various Lengths of Canalicular Stents in Volunteers [NA]
A completed clinical trial in healthy volunteers and individuals with dry eye to evaluate the safety and retention times of punctal plugs of…
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome [Phase 2, Phase 3]
This document reports the completion of a Phase 2/3 efficacy and safety study evaluating ecabet ophthalmic solution for dry eye disease.
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CLINICAL_TRIALS trial_result · 2013-03-11Clinical Trial Update: Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients [Phase 2]
Phase 2 clinical trial update from Alcon Research evaluating an anti-inflammatory treatment for Dry Eye Disease.
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CLINICAL_TRIALS trial_result · 2013-02-21Clinical Trial Update: Repeatability and Agreement of Anterior Segment Optical Coherence Tomography (AS-OCT) and Thermography [NA]
This clinical trial update reports on the repeatability and agreement between anterior segment optical coherence tomography (AS-OCT) and the…
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CLINICAL_TRIALS trial_result · 2013-02-08Clinical Trial Update: A Study of RX-10045 in the Treatment of Dry Eye Disease [Phase 2]
The document reports completion of a Phase 2 clinical trial evaluating RX-10045 for dry eye disease.
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CLINICAL_TRIALS trial_result · 2013-01-25Clinical Trial Update: Systane Ultra Versus Maxidex Versus Saline [NA]
A completed clinical trial comparing Systane Ultra, Maxidex, and saline for Dry Eye Disease.
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model [Phase 2]
Phase 2 dose-ranging study evaluating the safety and efficacy of subconjunctival sirolimus for dry eye in the CAE model has completed.
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Moisture Chamber Glasses for Dry Eye in Asian Population [NA]
This clinical trial update notes that the moisture chamber glasses study for dry eye in an Asian population has completed.
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: The Effects of a Single Intravenous Administration of Secukinumab (AIN457) or Canakinumab (ACZ885) in Dry Eye Patients [Phase 2]
Phase 2 study evaluating a single intravenous dose of secukinumab or canakinumab in dry eye disease; the trial is completed with results pos…
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CLINICAL_TRIALS trial_result · 2012-12-24Clinical Trial Update: Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye [Phase 2]
Phase 2 trial evaluating the safety and efficacy of thymosin beta-4 ophthalmic solution for dry eye. Results have been posted following comp…
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: A Study Assessing the Safety and Efficacy of DE-101 Ophthalmic Suspension in Dry Eye Patients [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of DE-101 ophthalmic suspension for Dry Eye Disease has completed.
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact Lenses and Before Insertion of Contact Lenses [Phase 1]
A Phase 1 study evaluated the safety and tolerability of chitosan-N-acetylcysteine eye drops in adults with dry eye disease while wearing co…
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CLINICAL_TRIALS trial_result · 2012-09-20Clinical Trial Update: A Prospective, Randomized, Double-Masked, Single Center, Clinical Comparison of the Use of Systane Ultra in the Management of Dry Eyes in Bilateral Eyes [Phase 4]
A Phase 4, prospective, randomized, double-masked trial at a single center evaluated Systane Ultra for managing bilateral dry eye and the st…
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: Dry Eye Assessment and Management: Feasibility Study [Phase 2, Phase 3]
A Phase 2/3 feasibility study of Dry Eye Assessment and Management completed with results posted in 2012, evaluating dry eye disease and ker…
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CLINICAL_TRIALS trial_result · 2012-07-18Clinical Trial Update: Physician's Evaluation of Cyclosporine Ophthalmic Emulsion 0.05%
Completed clinical trial evaluating cyclosporine ophthalmic emulsion 0.05% for dry eye disease; results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers [Phase 1]
Phase 1 study assessing the ocular tolerability of SYL1001 in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients [Phase 4]
A Phase 4 trial evaluating the effects of benzalkonium chloride (BAK) on the blood-aqueous barrier in pseudophakic patients with dry eye dis…
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CLINICAL_TRIALS trial_result · 2012-06-05Clinical Trial Update: Optimization of Assessment and Grading for Lid Wiper Epitheliopathy
Update on a completed clinical trial focusing on optimizing how lid wiper epitheliopathy is assessed and graded in dry eye disease.
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CLINICAL_TRIALS trial_result · 2012-03-02Clinical Trial Update: Study of Two Formulations of Cyclosporine Ophthalmic Emulsion in Healthy Volunteers and in Patients With Dry Eye [Phase 1]
Phase 1 study evaluating two formulations of cyclosporine ophthalmic emulsion in healthy volunteers and patients with dry eye disease; the t…
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CLINICAL_TRIALS trial_result · 2012-02-17Clinical Trial Update: A Clinical Evaluation Pilot Study of the Efficacy of Blink® Tears Lubricant Eye Drops for the Relief of Dry Eye Symptoms Following Implantation of Tecnis® Multifocal Introcular Lens [Phase 4]
Phase 4 clinical trial assessing whether Blink Tears Lubricant Eye Drops relieve dry eye symptoms after implantation of Tecnis multifocal in…
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: Evaluate the Ability of Systane Ultra to Improve Subjective Symptoms of Ocular Irritation Post 60 Min. Athletic Performance. [NA]
A completed clinical trial evaluating whether Systane Ultra eye drops reduce subjective ocular irritation and improve visual performance aft…