Dry Eye Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers [NA]
A pilot clinical trial evaluated the Bruder Eye Hydrating Compress for reducing contact lens discomfort and dry eye symptoms in contact lens…
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CLINICAL_TRIALS trial_result · 2018-05-15Clinical Trial Update: Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye Disease [Phase 2]
Phase 2 trial of Restasis X (cyclosporine ophthalmic formulation) for dry eye disease was terminated. Results from the study were posted in …
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Evaluation of the Efficacy and Safety of DM05 Versus Optive™ on the Treatment of Moderate to Severe Ocular Dryness [NA]
The trial compared DM05 to Optive for treating moderate to severe dry eye. It has completed and evaluated efficacy and safety.
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Optical Coherence Tomography of Tear Film Dynamics In-Vivo [NA]
This clinical trial update reports an in-vivo study of tear film dynamics using optical coherence tomography in Dry Eye Disease. The study s…
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CLINICAL_TRIALS research · 2018-04-18Clinical Trial Update: Functional MRI Study of Cortical Modifications to Light Stimulation in Patients With Photophobia [NA]
This clinical trial update describes a functional MRI study evaluating cortical changes in response to light stimulation in patients with ph…
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CLINICAL_TRIALS research · 2018-03-19Clinical Trial Update: Investigating the Effect of At Home Thermal Therapy on Dry Eye Patients With Meibomian Gland Dysfunction [NA]
This clinical trial update covers at-home thermal therapy for patients with Meibomian Gland Dysfunction and Dry Eye Disease; the current stu…
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CLINICAL_TRIALS trial_result · 2018-03-05Clinical Trial Update: An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome [Phase 3]
An extension study of KCT-0809 for dry eye in Sjögren's syndrome (Phase 3) has been terminated.
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease [Phase 2]
Phase 2 study evaluating pharmacodynamic activity of P-321 ophthalmic solution vs placebo in dry eye disease; study terminated with results …
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FDA approval · 2017-12-17FDA Approved: XIIDRA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for XIIDRA (lifitegrast) by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Ocular Surface Syndrome Post-lasik, Outcomes of Treatment With Platelet Rich Plasma [Phase 2]
Phase 2 trial update evaluating platelet-rich plasma for ocular surface syndrome with dry eye after LASIK. The study reports outcomes from t…
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CLINICAL_TRIALS trial_result · 2017-11-24Clinical Trial Update: LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease [Phase 2]
Phase 2 trial evaluating LME636 for relief of persistent ocular discomfort in severe dry eye disease; the study was completed and results we…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome [Phase 3]
Phase 3 long-term study of KCT-0809 for dry eye in patients with Sjögren's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease. [Phase 3]
Phase 3 trial evaluating the safety and efficacy of a new eye drop formulation for dry eye disease has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Ocular Surface Immune Response in Dry Eye Disease
The document reports on a completed clinical trial examining the ocular surface immune response in dry eye disease.
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: Lamelleye vs Comparator for the Treatment of Dry Eye Disease [NA]
A completed clinical trial (NCT03052140) comparing Lamelleye to a comparator for dry eye disease.
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CLINICAL_TRIALS research · 2017-08-24Clinical Trial Update: Automatic Self Transcending Meditation (ASTM) in Patients With Dry Eye Disease [NA]
This clinical trial update describes a study evaluating Automatic Self Transcending Meditation for Dry Eye Disease, with notes on related mo…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: The Effect of Ablation Depth on Dry Eye After LASIK Treatment of Myopia [NA]
A completed clinical trial evaluated whether the depth of laser ablation during LASIK for myopia influences the incidence and severity of dr…
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CLINICAL_TRIALS research · 2017-07-25Clinical Trial Update: A Natural History Study of Patients With Dry Eye
Allergan-sponsored natural history study of dry eye disease has completed, documenting observational data on the condition's natural course.
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: Influence of Perfluorohexyloctane (NovaTears) on Tear Film Thickness in Patients With Mild to Moderate Dry Eye Disease [NA]
Clinical trial update evaluating the effect of perfluorohexyloctane (NovaTears) on tear film thickness in patients with mild to moderate dry…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Digital Photography to Evaluate Dry Eye
An NEI-sponsored trial explored using digital photography to assess dry eye disease and has completed.
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: A Safety and Efficacy Study of Refresh Optive® Gel Drops in Patients With Dry Eye Disease [Phase 3]
Phase 3 trial update evaluating safety and efficacy of Refresh Optive Gel Drops for dry eye disease has completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Evaluation of Maintaining Visual Performance in Participants Who Engage in Electronic Visual Tasking While Using Restasis® [Phase 4]
A Phase 4 clinical trial evaluating whether Restasis can maintain visual performance in participants performing electronic visual tasks has …
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome [Phase 3]
Phase III study of KCT-0809 for dry eye in Sjögren's syndrome has completed, with the trial status shown as COMPLETED.
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Clinical Evaluation of Systane® Gel Drops in Dry Eye Subjects [NA]
Clinical trial evaluating Systane Gel Drops in dry eye subjects has completed, and results have been posted.
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: The Impact of Hypo-osmolar Drops on Contact Lens Comfort [NA]
A completed clinical trial evaluated hypo-osmolar eye drops for improving comfort in individuals with contact lens-related dry eye.