Dry Eye Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-08-24Clinical Trial Update: A Randomized, Controlled, Double-masked, Investigator-initiated Trial to Evaluate Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal Spray [Phase 4]
A Phase 4 randomized, double-masked, investigator-initiated trial evaluating tear film quality and stability in dry eye disease using OC-01 …
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: Evaluating the Efficacy of Dry Eye (DE) Disease Treatment Using Novel Tear Film Imager (TFI) [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating a novel Tear Film Imager for dry eye disease has completed.
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CLINICAL_TRIALS trial_result · 2022-07-06Clinical Trial Update: Dry Eye Disease Study With Brimonidine [Phase 2]
Phase 2 clinical trial update for brimonidine in dry eye disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Effect of Topical Antioxidants in Dry Eye Disease and Diabetic Retinopathy [Phase 2]
Phase 2 trial investigating topical antioxidants for dry eye disease and diabetic retinopathy, status currently unknown.
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CLINICAL_TRIALS trial_result · 2022-06-08Clinical Trial Update: Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study) [Phase 2]
Phase 2 trial update for OC-01 nasal spray (MYSTIC Study) evaluating chronic efficacy on signs of dry eye disease; study completed with resu…
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CLINICAL_TRIALS trial_result · 2022-06-06Clinical Trial Update: Study of Brimonidine Tartrate Nanoemulsion Eye Drop Solution in the Treatment of Dry Eye Disease (DED) [Phase 3]
Phase 3 trial for brimonidine tartrate nanoemulsion eye drops in dry eye disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-05-26Clinical Trial Update: A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease [Phase 2]
Novartis conducted a Phase 2 trial comparing ECF843 to vehicle in subjects with dry eye disease. The study is completed and results were pos…
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease [Phase 3]
Phase 3 trial assessing CsA ophthalmic gel for safety and efficacy in moderate to severe dry eye disease completed.
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CLINICAL_TRIALS trial_result · 2022-04-18Clinical Trial Update: Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease [Phase 4]
A Phase 4 trial comparing Lipiflow treatment alone versus Lipiflow plus Dextenza for dry eye disease completed.
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CLINICAL_TRIALS trial_result · 2022-04-18Clinical Trial Update: Concentration of Ofloxacin Into the Aqueous Humour of Patients With Dry Eye Disease [Phase 4]
Phase 4 clinical trial evaluating concentration of ofloxacin in the aqueous humor of patients with dry eye disease has completed.
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CLINICAL_TRIALS trial_result · 2022-03-23Clinical Trial Update: The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED [Phase 4]
Phase 4 update assessing cellular responses via in vivo confocal microscopy and evaluating the long-term efficacy and safety of topical ster…
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CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: RPS InflammaDry Detector™ to Determine MMP-9 Levels in Tears
Clinical trial update on the RPS InflammaDry Detector for measuring MMP-9 levels in tears in dry eye disease; study completed with results p…
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CLINICAL_TRIALS trial_result · 2022-02-18Clinical Trial Update: Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients [Phase 3]
Phase 3 clinical trial evaluating TJO-087 for moderate to severe dry eye disease; current status is unknown.
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CLINICAL_TRIALS trial_result · 2022-02-03Clinical Trial Update: Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study) [Phase 2]
Phase 2 trial evaluating OC-02 nasal spray for dry eye disease has completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-01-26Clinical Trial Update: A Study to Assess Efficacy of HL036 in Subjects With Dry Eyes [Phase 2]
Phase 2 trial update evaluating HL036 for dry eye completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-12-29Clinical Trial Update: Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation [Phase 2]
Phase 2 trial evaluating OC-01 nasal spray for stimulation of goblet cells and meibomian glands in dry eye disease has completed with posted…
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CLINICAL_TRIALS trial_result · 2021-12-14Clinical Trial Update: Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study) [Phase 2]
Phase 2 clinical trial update for OC-02 nasal spray (The PEARL Study) evaluating efficacy in signs and symptoms of Dry Eye Disease; study st…
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CLINICAL_TRIALS trial_result · 2021-12-06Clinical Trial Update: Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease [Phase 2]
Phase 2 clinical trial evaluating the effect of Traditional Chinese Medicine on tear secretion and tear cytokines in patients with dry eye d…
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CLINICAL_TRIALS trial_result · 2021-11-30Clinical Trial Update: IIT Assessing OC-01Nasal Spray on Symptoms of DED Following CXL [Phase 2]
A Phase 2 clinical trial update evaluating OC-01 nasal spray for symptoms of Dry Eye Disease after corneal collagen crosslinking.
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CLINICAL_TRIALS trial_result · 2021-11-22Clinical Trial Update: Evaluation of the Efficacy and Safety of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease [Phase 3]
Phase 3 clinical trial update for OC-01 nasal spray in dry eye disease, reporting results upon completion.
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CLINICAL_TRIALS trial_result · 2021-11-22Clinical Trial Update: Evaluation of the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease [Phase 2, Phase 3]
Long-term follow-up data from Phase 2/3 trials evaluating OC-01 nasal spray for dry eye disease have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2021-11-22Clinical Trial Update: Optimization of the Treatment of Dry Eye Disease Caused by Meibomian Gland Dysfunction [Phase 4]
Phase 4 trial update on optimizing treatment for dry eye disease due to meibomian gland dysfunction has been completed.
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CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: Evaluation of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease [Phase 2]
Phase 2 clinical trial evaluating OC-01 Nasal Spray for signs and symptoms of Dry Eye Disease has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: Efficacy of Xiidra in Dry Eye Disease After Collagen Cross Linking [Phase 4]
Phase 4 clinical trial evaluating efficacy of Xiidra in dry eye disease following collagen cross-linking.
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye Disease [NA]
A terminated clinical trial investigating goblet cell degranulation triggered by an intranasal tear neurostimulator for dry eye disease; res…