Dry Eye Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease [Phase 3]
Phase 3 trial update for SJP-0035 in dry eye disease completed.
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CLINICAL_TRIALS trial_result · 2019-04-05Clinical Trial Update: Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye Disease [Phase 2]
Phase 2 clinical trial update for AGN-223575 ophthalmic suspension in dry eye disease, reporting safety, efficacy, tolerability, and pharmac…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Clinical Study to Evaluate the Efficacy of Ectoin® Containing Eye Spray for Treatment of Dry Eye Disease [NA]
A completed clinical study evaluated the efficacy of Ectoin-containing eye spray for dry eye disease. The trial (NCT03519815) was conducted …
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED) [Phase 3]
Phase 3 double-masked trial of SYL1001 for Dry Eye Disease has completed.
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Intense Pulse Light Treatment With Meibomian Gland Expression of the Upper Eyelids in Dry Eye Disease [NA]
A completed clinical trial evaluated intense pulsed light treatment with meibomian gland expression for dry eye disease. Results were posted…
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CLINICAL_TRIALS trial_result · 2018-12-14Clinical Trial Update: Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca [Phase 2, Phase 3]
A phase 2/3 dose-ranging trial evaluated the safety and efficacy of OTX-101 for keratoconjunctivitis sicca (dry eye disease); the study has …
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CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: Use of 5.0% Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease in Contact Lens Wearers [Phase 4]
A Phase 4 trial investigating 5.0% lifitegrast ophthalmic solution for dry eye disease in contact lens wearers has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease [Phase 2]
Phase 2 clinical trial evaluating P-321 ophthalmic solution vs placebo in dry eye disease was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Clinical Evaluation of Systane® Balance in Dry Eye Subjects [NA]
Clinical trial update for Systane Balance in dry eye subjects; study terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED) [Phase 2]
Phase 2 clinical trial update for CyclASol in moderate to severe dry-eye disease completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers [NA]
A pilot clinical trial evaluated the Bruder Eye Hydrating Compress for reducing contact lens discomfort and dry eye symptoms in contact lens…
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CLINICAL_TRIALS trial_result · 2018-05-15Clinical Trial Update: Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye Disease [Phase 2]
Phase 2 trial of Restasis X (cyclosporine ophthalmic formulation) for dry eye disease was terminated. Results from the study were posted in …
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Evaluation of the Efficacy and Safety of DM05 Versus Optive™ on the Treatment of Moderate to Severe Ocular Dryness [NA]
The trial compared DM05 to Optive for treating moderate to severe dry eye. It has completed and evaluated efficacy and safety.
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Optical Coherence Tomography of Tear Film Dynamics In-Vivo [NA]
This clinical trial update reports an in-vivo study of tear film dynamics using optical coherence tomography in Dry Eye Disease. The study s…
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CLINICAL_TRIALS trial_result · 2018-03-05Clinical Trial Update: An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome [Phase 3]
An extension study of KCT-0809 for dry eye in Sjögren's syndrome (Phase 3) has been terminated.
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease [Phase 2]
Phase 2 study evaluating pharmacodynamic activity of P-321 ophthalmic solution vs placebo in dry eye disease; study terminated with results …
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Ocular Surface Syndrome Post-lasik, Outcomes of Treatment With Platelet Rich Plasma [Phase 2]
Phase 2 trial update evaluating platelet-rich plasma for ocular surface syndrome with dry eye after LASIK. The study reports outcomes from t…
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CLINICAL_TRIALS trial_result · 2017-11-24Clinical Trial Update: LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease [Phase 2]
Phase 2 trial evaluating LME636 for relief of persistent ocular discomfort in severe dry eye disease; the study was completed and results we…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome [Phase 3]
Phase 3 long-term study of KCT-0809 for dry eye in patients with Sjögren's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease. [Phase 3]
Phase 3 trial evaluating the safety and efficacy of a new eye drop formulation for dry eye disease has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Ocular Surface Immune Response in Dry Eye Disease
The document reports on a completed clinical trial examining the ocular surface immune response in dry eye disease.
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: Lamelleye vs Comparator for the Treatment of Dry Eye Disease [NA]
A completed clinical trial (NCT03052140) comparing Lamelleye to a comparator for dry eye disease.
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: The Effect of Ablation Depth on Dry Eye After LASIK Treatment of Myopia [NA]
A completed clinical trial evaluated whether the depth of laser ablation during LASIK for myopia influences the incidence and severity of dr…
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: Influence of Perfluorohexyloctane (NovaTears) on Tear Film Thickness in Patients With Mild to Moderate Dry Eye Disease [NA]
Clinical trial update evaluating the effect of perfluorohexyloctane (NovaTears) on tear film thickness in patients with mild to moderate dry…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Digital Photography to Evaluate Dry Eye
An NEI-sponsored trial explored using digital photography to assess dry eye disease and has completed.