Drug-resistant Epilepsy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of N-acetylcysteine in children with drug-resistant epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl [NA]
First-in-human study of a vagus nerve stimulation device by Synergia Medical for drug-resistant epilepsy; the trial is currently active but …
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Exploring the Characteristics of Epileptogenic Foci in Drug-Resistant Epilepsy Based on Multimodal Imaging Technology
A clinical trial update investigating the characteristics of epileptogenic foci in drug-resistant epilepsy using multimodal imaging (MRI and…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: CANnabinoids for Drug Resistant Epilepsy (DRE) in Adults and Children [Phase 2]
This Clinical Trial Update describes a Phase 2 study of CANnabinoids for drug-resistant epilepsy in adults and children, which is not yet re…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: RNS System RESPONSE Study [NA]
The NeuroPace RNS System RESPONSE study was terminated during its course.
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Contribution of Genetics, Non-invasive Methods and Neuropsychology in Focal Cryptogenic Epilepsies [NA]
This completed clinical trial investigated the contribution of genetics, non-invasive methods, and neuropsychology in focal cryptogenic epil…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Cartography of Social Cognition Network and Their Alterations in Patients With Epilepsy [NA]
This is a recruiting clinical trial in Paris studying social cognition networks and their alterations in patients with epilepsy, including t…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Percutaneous Repair for Drug - Resistant Epilepsy by Intervention of Closing the Patent Foramen Ovale（PREDICT-PFO Trial） [NA]
A clinical trial is evaluating percutaneous closure of patent foramen ovale as a treatment for drug-resistant epilepsy and is currently recr…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Evaluating Modulation Effects of Temporal Interference Using SEEG [NA]
The document reports a clinical trial evaluating temporal interference modulation using SEEG for drug-resistant epilepsy, sponsored by Xuanw…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies
Clinical trial update describing an extended access program using lorcaserin to treat Dravet syndrome and other refractory epilepsies.
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: The GABAergic Inhibitory System in Drug Resistant Epilepsy [NA]
A completed clinical trial from the University of Coimbra investigates the role of the GABAergic inhibitory system in drug-resistant epileps…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: BOTOX Effects on Seizure Severity and Susceptibility [Phase 4]
A Phase 4 trial evaluating Botox (onabotulinumtoxinA) for effects on seizure severity and susceptibility in drug-resistant focal seizures wa…
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Sirolomus Adjuvant Treatment of Focal Refractory Epilepsy (SATFRE) [EARLY_Phase 1]
A Phase 1 early trial (SATFRE) evaluating sirolomus as an adjuvant treatment for focal refractory epilepsy is currently recruiting at Xuanwu…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Propranolol Adjuvant Treatment of Focal Refractory Epilepsy (PATFRE) [EARLY_Phase 1]
This clinical trial update outlines a Phase 1 study of propranolol as an adjuvant treatment for focal refractory epilepsy, which is not yet …
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Temporal Interference for Drug Resistant Epilepsy [NA]
A recruiting clinical trial at Xuanwu Hospital in Beijing is evaluating Temporal Interference for drug-resistant epilepsy.
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.
Completed clinical trial registry update describing subjects with drug-resistant epilepsy treated with the VNS Therapy System by LivaNova.
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients
An update on a clinical trial investigating biomarkers (genes, proteins, and metabolites) in patients with drug-resistant epilepsy and traum…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Clinical Utility and Safety of Human Umbilical Cord Mesenchymal Stem Cell Secretome in Drug Resistant Epilepsy Single Center, Non-randomized, Phase I Clinical Trial [Phase 1]
A Phase 1 clinical trial assessing the safety and potential utility of human umbilical cord mesenchymal stem cell secretome for drug-resista…
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CLINICAL_TRIALS trial_result · 2024-07-12Clinical Trial Update: Vitamine D in Drug Resistant Epilepsy [Phase 3]
Phase 3 trial evaluating Vitamin D as an adjunct therapy for drug-resistant epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy [NA]
A completed clinical trial evaluated the effects of a low glycemic index diet on children with drug-resistant epilepsy, examining outcomes r…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Impact of Mindfulness Intervention on Quality of Life in Patients With Drug-resistant Epilepsy. [NA]
A clinical trial evaluating mindfulness to improve quality of life in patients with drug-resistant epilepsy is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Investigating Surprise Signals in the Anterior Insula
A clinical trial update from University Hospital, Geneva indicates the study investigating surprise signals in the anterior insula is curren…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy [Phase 1]
A Phase 1 trial is evaluating leucine-enriched essential amino acid powder added to a classic ketogenic diet for refractory epilepsy and dru…
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CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients With Drug Resistant Epilepsy [Phase 2]
Phase 2 clinical trial update evaluating efficacy, safety, and pharmacokinetics of ES-481 in adults with drug resistant epilepsy.
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CLINICAL_TRIALS trial_result · 2023-01-26Clinical Trial Update: The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy Children [Phase 4]
Phase 4 trial update examining the benefit and safety of older generation anti-epileptic drugs in children with drug-resistant epilepsy.