Drug-resistant Epilepsy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Coenzyme Q10 as Adjunctive Therapy in Drug-Resistant Epilepsy [NA]
A completed clinical trial evaluated Coenzyme Q10 as an adjunctive therapy for drug-resistant epilepsy.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy [Phase 2, Phase 3]
A Phase 2/3 study evaluating Vatiquinone for mitochondrial disease in participants with refractory epilepsy has been terminated, and results…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Recording "Fast Ripples" Using Microelectrodes During Stereo-encephalography in Patients With Drug-resistant Partial Epilepsy [NA]
A completed clinical trial evaluating recording fast ripples with microelectrodes during stereo-encephalography in people with drug-resistan…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Circulating microRNAs as Biomarkers of RESPIratory Dysfunction in Patients With Refractory epilePSY [NA]
This completed clinical trial evaluated circulating microRNAs as biomarkers of respiratory dysfunction in patients with drug-resistant epile…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Modulation of Emotion Perception in Humans Via Amygdala Stimulation [NA]
ClinicalTrials.gov reports a completed study evaluating amygdala stimulation to modulate emotion perception in humans, with results posted o…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy [Phase 2]
Phase 2 clinical trial evaluating subanesthetic intravenous ketamine for drug-resistant epilepsy is currently recruiting to assess efficacy.
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Efficacy of Low Glycemic Index Diet Versus Classic Ketogenic Diet in Pediatric Epilepsy Treatment [NA]
A completed clinical trial compared a low glycemic index diet to a classic ketogenic diet in pediatric epilepsy to evaluate relative efficac…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of N-acetylcysteine in children with drug-resistant epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl [NA]
First-in-human study of a vagus nerve stimulation device by Synergia Medical for drug-resistant epilepsy; the trial is currently active but …
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: RNS System RESPONSE Study [NA]
The NeuroPace RNS System RESPONSE study was terminated during its course.
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Contribution of Genetics, Non-invasive Methods and Neuropsychology in Focal Cryptogenic Epilepsies [NA]
This completed clinical trial investigated the contribution of genetics, non-invasive methods, and neuropsychology in focal cryptogenic epil…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies
Clinical trial update describing an extended access program using lorcaserin to treat Dravet syndrome and other refractory epilepsies.
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: The GABAergic Inhibitory System in Drug Resistant Epilepsy [NA]
A completed clinical trial from the University of Coimbra investigates the role of the GABAergic inhibitory system in drug-resistant epileps…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: BOTOX Effects on Seizure Severity and Susceptibility [Phase 4]
A Phase 4 trial evaluating Botox (onabotulinumtoxinA) for effects on seizure severity and susceptibility in drug-resistant focal seizures wa…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.
Completed clinical trial registry update describing subjects with drug-resistant epilepsy treated with the VNS Therapy System by LivaNova.
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CLINICAL_TRIALS trial_result · 2024-07-12Clinical Trial Update: Vitamine D in Drug Resistant Epilepsy [Phase 3]
Phase 3 trial evaluating Vitamin D as an adjunct therapy for drug-resistant epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy [NA]
A completed clinical trial evaluated the effects of a low glycemic index diet on children with drug-resistant epilepsy, examining outcomes r…
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CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients With Drug Resistant Epilepsy [Phase 2]
Phase 2 clinical trial update evaluating efficacy, safety, and pharmacokinetics of ES-481 in adults with drug resistant epilepsy.
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CLINICAL_TRIALS trial_result · 2023-01-26Clinical Trial Update: The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy Children [Phase 4]
Phase 4 trial update examining the benefit and safety of older generation anti-epileptic drugs in children with drug-resistant epilepsy.
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CLINICAL_TRIALS trial_result · 2021-12-29Clinical Trial Update: Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy [Phase 2]
Phase 2 study evaluating padsevonil as adjunctive therapy for drug-resistant focal-onset seizures was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy [Phase 3]
Phase 3 trial evaluating padsevonil for drug-resistant focal-onset seizures was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-04-09Clinical Trial Update: Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy [Phase 2]
Phase 2 study evaluating padsevonil as an adjunctive treatment for drug-resistant focal-onset seizures completed with results posted in 2021…
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CLINICAL_TRIALS trial_result · 2020-09-11Clinical Trial Update: Cannabis Extract in Refractory Epilepsy Study [Phase 3]
A Phase 3 trial evaluating a cannabis extract for drug-resistant epilepsy was terminated.
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Comparison of Efficacy of LGIT and MAD Among Children With Drug Resistant Epilepsy [Phase 4]
Phase 4 clinical trial comparing efficacy of LGIT and MAD in children with drug-resistant epilepsy.
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Comparison Between Efficacy of Daily and Intermittent Low Glycemic Index Therapy Diet [NA]
This clinical trial update compares daily versus intermittent low glycemic index therapy diets in individuals with drug-resistant epilepsy. …