Dilated Cardiomyopathy
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study) [Phase 1, Phase 2]
The EMERALD study is evaluating endocardial delivery of allogeneic iPSC-derived cardiomyocyte spheroids for heart failure with systolic dysf…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
This clinical trial update notes enrollment by invitation for a Johns Hopkins study deriving human induced pluripotent stem cells to model h…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry
A multicenter registry in Brazil's public health system aims to improve care for hereditary cardiovascular diseases by enrolling patients ac…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy
A clinical trial at Zhejiang University is assessing the prognostic value of coronary microvascular dysfunction in patients with Dilated Car…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Assessment of the Predictive Value of Anti-beta1AR and Anti-L-CaC Antibodies in the Evolution to Dilated Cardiomyopathy in Patients With Acute Viral Myocarditis
A clinical trial update examining whether anti-beta1 adrenergic receptor antibodies and anti-L-CaC antibodies can predict progression from a…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM)
A clinical trial examining the natural history of adults with BAG3-related dilated cardiomyopathy (BAG3 DCM) and its progression.
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study [NA]
The CORCINCH-HF trial evaluating the AccuCinch Ventricular Restoration System for symptomatic heart failure with reduced ejection fraction i…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Comparative Efficacy of ARNI Versus ACE Inhibitor Therapy in Egyptian Children With Dilated Cardiomyopathy
A planned clinical trial in Egypt compares the efficacy of an ARNI (sacubitril/valsartan) versus an ACE inhibitor in children with dilated c…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Examining the Effects of Mitochondrial Oxidative Stress in DCM [Phase 2]
A Phase 2 clinical trial investigating the effects of mitochondrial oxidative stress in Dilated Cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Intraventricular Stasis In Cardiovascular Disease
A completed clinical trial update on intraventricular stasis in cardiovascular disease. The study involves patients with dilated cardiomyopa…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM) [Phase 1]
This is a Phase 1 open-label study evaluating the safety of intravenously delivered allogeneic neonatal mesenchymal cells (nMSCs) in pediatr…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: UIC Multi-Ethnic DCM Registry
The University of Illinois at Chicago is conducting the UIC Multi-Ethnic Dilated Cardiomyopathy (DCM) Registry, a recruiting clinical trial …
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Repurposing Empagliflozin for DMD-associated Cardiomyopathy in Children 6-18 Years of Age [Phase 2]
Phase 2 clinical trial protocol repurposing empagliflozin for Duchenne muscular dystrophy–associated dilated cardiomyopathy in children aged…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Micophenolate Mofetil Versus Azathioprine in Myocarditis [Phase 3]
A Phase 3 trial comparing mycophenolate mofetil to azathioprine in lymphocytic myocarditis and related cardiomyopathy conditions has complet…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Pediatric Cardiomyopathy Mutation Analysis
A pediatric study at Indiana University is recruiting to analyze genetic mutations associated with various forms of cardiomyopathy.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Block With Cardiac Resynchronization Therapy
A clinical trial update indicates a study evaluating absolute coronary flow in patients with heart failure with reduced ejection fraction an…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Protein A Immunoadsorption in Dilated Cardiomyopathy (RPIA-DCM) [NA]
A clinical trial evaluating protein A immunoadsorption for dilated cardiomyopathy (RPIA-DCM) is currently recruiting. The sponsor is Union H…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities [Phase 2]
A Phase 2 exploratory trial of Danicamtiv in primary dilated cardiomyopathy, including familial/genetic cases, was terminated and results ha…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Evaluating the Prognostic Impact of Anti-β1AR Antibodies and Anti-L-CaC Antibodies in Patients With Dilated Cardiomyopathy
This clinical trial update indicates ongoing recruitment to evaluate the prognostic impact of anti-β1AR antibodies and anti-L-CaC antibodies…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: A Clinical Study of Immunoadsorption Therapy for Dilated Cardiomyopathy [NA]
The trial evaluating immunoadsorption therapy for dilated cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations [NA]
Completed clinical trial assessing health-related quality of life and physical activity in children with cardiac malformations, sponsored by…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Mayo AVC Registry and Biobank
This entry describes Mayo Clinic's AVC Registry and Biobank (NCT03049254), an ongoing registry and biobank focused on arrhythmogenic right v…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy [Phase 1]
Phase 1 clinical trial assessing modulation of SERCA2a to improve intra-myocytic calcium trafficking in Duchenne muscular dystrophy-associat…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
This entry describes an ongoing clinical trial evaluating AI-enabled, direct-from-ECG assessment of ejection fraction severity using the COR…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation
This clinical trial update describes a study at IRCCS Azienda Ospedaliero-Universitaria di Bologna that aims to characterize patients with v…