Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2015-05-06Clinical Trial Update: The Prognostic Value of Interim PET/CT After 2 Cycles of Chemotherapy in Predicting Progression of Non Hodgkins Lymphoma
The trial evaluating whether interim PET/CT after two cycles of chemotherapy can predict progression in non-Hodgkin lymphoma has been withdr…
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CLINICAL_TRIALS withdrawal · 2015-04-17Clinical Trial Update: A Comparative Study Of Iodine I 131 Tositumomab Therapeutic Regimen Versus Ibritumomab Tiuxetan Therapeutic Regimen [Phase 3]
A Phase 3 trial comparing two radioimmunotherapy regimens (I-131 tositumomab vs ibritumomab tiuxetan) for follicular and other non-Hodgkin l…
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Interleukin-12 in Treating Patients With Previously Treated Non-Hodgkin's Lymphoma or Hodgkin's Disease [Phase 2]
Phase 2 trial update reporting completion of a study evaluating interleukin-12 in patients with various previously treated non-Hodgkin lymph…
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Monoclonal Antibody Therapy and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial evaluating monoclonal antibody therapy with combination chemotherapy in advanced diffuse large B-cell lymphoma (DLBCL).
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER) [Phase 2]
Phase 2 GATHER trial evaluating obinutuzumab in combination with CHOP for previously untreated advanced diffuse large B-cell lymphoma; the s…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers [Phase 1]
First-in-human Phase 1 trial assessing safety, tolerability, and preliminary efficacy of an anti-CXCR4 antibody in acute myeloid leukemia an…
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: Prospective Cohort Study With Central Nervous System Evaluation in Diffuse Large B-cell Lymphoma [NA]
A completed prospective cohort study evaluating central nervous system involvement in diffuse large B-cell lymphoma was reported, sponsored …
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: A Randomized Phase IIb Placebo-Controlled Study of R-ICE Chemotherapy With and Without SGN-40 for Patients With DLBCL [Phase 2]
A Phase IIb randomized trial evaluating R-ICE chemotherapy with and without SGN-40 for diffuse large B-cell lymphoma/non-Hodgkin lymphoma ha…
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Feasibility Study of a 60 Minute Rapid Infusion Rituximab Protocol in Patients With B-cell Malignancies [Phase 2]
A Phase 2 feasibility study evaluating a 60-minute rapid infusion rituximab protocol in patients with indolent or intermediate-grade B-cell …
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CLINICAL_TRIALS trial_result · 2015-02-18Clinical Trial Update: Rituximab, Combination Chemotherapy, and 90-Yttrium Ibritumomab Tiuxetan for Patients With Stage I or II Non-Hodgkin's Lymphoma [Phase 2]
A Phase 2 trial evaluating Rituximab with chemotherapy and 90-yttrium ibritumomab tiuxetan in patients with Stage I or II non-Hodgkin lympho…
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies [Phase 1]
A Phase 1 pilot study evaluated co-infusing ex vivo expanded cord blood cells with an unmanipulated cord blood unit in patients undergoing c…
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CLINICAL_TRIALS trial_result · 2015-01-30Clinical Trial Update: The Response Study of Yt90-Zevalin in Patients With Diffuse Large B-cell Lymphoma After 6 Cycles of CHOP [Phase 2]
A Phase 2 trial update evaluating Yttrium-90 Zevalin in patients with Diffuse Large B-cell Lymphoma after 6 cycles of CHOP has been complete…
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: Study of SGN-40 in Patients With Relapsed Diffuse Large B-Cell Lymphoma [Phase 2]
A completed Phase 2 trial evaluating SGN-40 (dacetuzumab) in patients with relapsed diffuse large B-cell lymphoma and other non-Hodgkin lymp…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Bortezomib and Flavopiridol in Treating Patients With Recurrent or Refractory Indolent B-Cell Neoplasms [Phase 1]
A Phase 1 trial evaluating the combination of bortezomib and flavopiridol in patients with recurrent or refractory indolent B-cell neoplasms…
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CLINICAL_TRIALS trial_result · 2014-12-18Clinical Trial Update: Trial to Define the Safety and Tolerability of SGN-40, Rituximab, and Gemcitabine in Patients With DLBCL [Phase 1]
A Phase 1 trial assessed the safety and tolerability of combining SGN-40 (dacetuzumab) with rituximab and gemcitabine in patients with diffu…
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CLINICAL_TRIALS trial_result · 2014-12-09Clinical Trial Update: Assessment of Cellular Proliferation in Tumors by Positron Emission Tomography (PET) Using [18F]ISO-1 [Phase 1]
Phase 1 clinical trial update evaluating tumor cellular proliferation using the PET radiotracer [18F]ISO-1 in patients with breast cancer, h…
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CLINICAL_TRIALS trial_result · 2014-12-09Clinical Trial Update: PTK787 in Refractory or Relapsed Diffuse Large Cell Lymphoma [Phase 2]
A Phase 2 trial of PTK787 (vatalanib) for refractory or relapsed diffuse large B-cell lymphoma was terminated.
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CLINICAL_TRIALS trial_result · 2014-12-04Clinical Trial Update: Gemcitabine Hydrochloride, Cyclophosphamide, Vincristine Sulfate, Prednisolone, and Rituximab in Treating Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating a gemcitabine hydrochloride–cyclophosphamide–vincristine sulfate–prednisolone–rituximab regimen in newly d…
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: Combination of SAR3419 and Rituximab in Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
This is a Phase 2 trial update on the combination of SAR3419 and rituximab in relapsed/refractory diffuse large B-cell lymphoma. The update …
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CLINICAL_TRIALS trial_result · 2014-11-07Clinical Trial Update: RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating RO4929097 in combination with capecitabine in patients with refractory solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: A Study of MabThera/Rituxan (Rituximab) in Patients With Relapsed Centroblastic Centrocytic Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 study of Rituximab (MabThera/Rituxan) in patients with relapsed centroblastic-centrocytic non-Hodgkin lymphoma has completed, with r…
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CLINICAL_TRIALS trial_result · 2014-10-27Clinical Trial Update: Everolimus Plus Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma [Phase 2]
Phase 2 study evaluating everolimus plus rituximab in relapsed/refractory diffuse large B-cell lymphoma has completed, with results posted i…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Ofatumumab Versus Rituximab Salvage Chemoimmunotherapy Followed by Autologous Stem Cell Transplant in Relapsed or Refractory Diffuse Large B Cell Lymphoma [Phase 3]
Phase 3 trial comparing Ofatumumab versus Rituximab salvage chemoimmunotherapy followed by autologous stem cell transplant in relapsed or re…
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CLINICAL_TRIALS trial_result · 2014-10-08Clinical Trial Update: Pilot Study of dMRI as a Tool for Early Evaluation of Tumor Response in Diffuse Large B-cell Lymphoma
Pilot study evaluating diffusion MRI as a tool for early evaluation of tumor response in diffuse large B-cell lymphoma; the trial was termin…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports a terminated phase 1/2 trial evaluating fenretinide with rituximab for B-cell non-Hodgkin lymphomas; …