Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: A Phase II Trial of Ifosfamide, Etoposide, Cytarabine, and Methotrexate (IVAM) Chemotherapy for Refractory or Relapsed Diffuse Large B Cell Lymphoma [Phase 2]
Phase II trial evaluating IVAM chemotherapy (Ifosfamide, Etoposide, Cytarabine, Methotrexate) for refractory or relapsed diffuse large B-cel…
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: Chidamide Combined With R-GDP in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
A Phase 2 trial evaluating chidamide in combination with R-GDP for relapsed or refractory diffuse large B-cell lymphoma (DLBCL).
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CLINICAL_TRIALS withdrawal · 2017-12-07Clinical Trial Update: Early Phase Evaluation of ABC294640 in Patients With Refractory/Relapsed Diffuse Large B-cell Lymphoma or Kaposi Sarcoma [Phase 1, Phase 2]
Clinical trial update shows the early-phase study of ABC294640 (opaganib) in refractory/relapsed diffuse large B-cell lymphoma and Kaposi sa…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: A Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell Lymphomas [Phase 1]
Phase I study of alisertib combined with R-EPOCH for myc-positive aggressive B-cell lymphomas has been terminated.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: DA-EPOCH-Rituximab/Metformin (RM) for Double Hit Lymphoma [Phase 2]
Phase 2 trial of DA-EPOCH-R Rituximab with Metformin for diffuse large B-cell lymphoma (double-hit) was terminated; results were posted in 2…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Dose Escalation Study in Patients With Relapsed or Refractory DLBCL and MyD88 L265P Mutation [Phase 1, Phase 2]
Idera Pharmaceuticals reported results from a phase 1/2 dose-escalation trial in patients with relapsed or refractory diffuse large B-cell l…
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: Chidamide Plus R-CHOP in Elderly DLBCL [Phase 2]
This document notes a Phase 2 clinical trial evaluating chidamide in combination with R-CHOP for elderly patients with Diffuse large B-cell …
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: A Study of Bortezomib Plus GDP in the Treatment of Refractory and Relapsed Non-GCB DLBCL [Phase 2]
A Phase 2 study evaluating the addition of bortezomib to GDP (gemcitabine, dexamethasone, cisplatin) chemotherapy in patients with refractor…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: An Observational Study of MabThera/Rituxan (Rituximab) Plus Chemotherapy As First-Line Treatment in Patients With Diffuse Large B-Cell Lymphoma or Follicular Lymphoma
This clinical trial update reports on an observational study of Rituxan/MabThera (rituximab) plus chemotherapy as first-line treatment for d…
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: R-CEOP-90/R-CEOP-70 Versus R-CHOP-50 in the Treatment of Diffuse Large B-cell Lymphoma and Follicular Lymphoma Grade 3B [Phase 3]
Phase 3 randomized trial comparing R-CEOP-90/70 versus R-CHOP-50 for Diffuse large B-cell lymphoma and Follicular lymphoma grade 3B; current…
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CLINICAL_TRIALS trial_result · 2017-10-30Clinical Trial Update: Study to Evaluate Efficacy and Tolerance of R-GemOx in DLBCL and MCL [Phase 2]
Phase 2 study of the R-GemOx regimen (rituximab, gemcitabine, and oxaliplatin) evaluating efficacy and tolerance in diffuse large B-cell lym…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Factors Influencing Hepatitis B Virus Reactivation in Lymphoma Patients Treated With Rituximab
This completed trial evaluated factors associated with hepatitis B reactivation in patients with diffuse large B-cell lymphoma or follicular…
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CLINICAL_TRIALS research · 2017-10-24Clinical Trial Update: Thalidomide Combined With R-CHOP in Newly Diagnosed，Untreated Double-expressor Diffuse Large B-Cell Lymphoma Patients [Phase 3]
A Phase 3 clinical trial is evaluating thalidomide in combination with R-CHOP for newly diagnosed, untreated double-expressor diffuse large …
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: A Safety Study of SGN-CD19A for B-Cell Lymphoma [Phase 1]
Phase 1 safety study of SGN-CD19A in various B-cell lymphomas has completed; the update summarizes safety results across multiple indication…
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Study of Bendamustine and Ofatumumab in Elderly Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma Who Are Poor Candidates for R-CHOP Chemotherapy [Phase 2]
A Phase 2 clinical trial evaluated bendamustine plus ofatumumab in elderly patients with newly diagnosed diffuse large B-cell lymphoma who a…
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CLINICAL_TRIALS research · 2017-10-12Clinical Trial Update: BUCY+VP-16 vs BUCY Conditioning Regimen for DLBCL Undergoing Auto-HSCT [Phase 2, Phase 3]
This clinical trial update compares BUCY+VP-16 versus BUCY conditioning in patients with diffuse large B-cell lymphoma undergoing autologous…
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CLINICAL_TRIALS research · 2017-10-11Clinical Trial Update: Role of CX3CR1-expressing Cells in Hematologic Malignancy
A clinical trial update examining the role of CX3CR1-expressing cells in hematologic malignancies, including Diffuse Large B-Cell Lymphoma a…
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CLINICAL_TRIALS trial_result · 2017-10-10Clinical Trial Update: Occupational Exposure to Pesticides in the Prognosis of Lymphomas
A clinical trial assessing the impact of occupational pesticide exposure on prognosis in patients with diffuse large B-cell lymphoma has bee…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: Rituximab, Cyclophosphamide, and G-CSF Followed By Combination Chemotherapy in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant Followed By Rituximab and GM-CSF for Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial evaluating rituximab, cyclophosphamide, and G-CSF followed by combination chemotherapy with rituximab and GM-CSF for refractor…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study Evaluating Inotuzumab Ozogamicin (CMC-544) Plus Rituximab In Diffuse Large B-Cell Non-Hodgkin's Lymphoma [Phase 2]
A Phase 2 study evaluated the combination of inotuzumab ozogamicin with rituximab in patients with diffuse large B-cell lymphoma. The trial …
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA) [Phase 3]
Phase 3 trial comparing obinutuzumab plus CHOP vs rituximab plus CHOP in CD20-positive diffuse large B-cell lymphoma was terminated with res…
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Comparison of HD Chemotherapy Followed by Auto-transplant and R-CHOP in High Risk Patients With DLBCL. [Phase 3]
Phase 3 trial comparing high-dose chemotherapy with autologous stem cell transplant versus R-CHOP in high-risk diffuse large B-cell lymphoma…
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Everolimus, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Untreated Diffuse Large B-Cell Lymphoma [Phase 1]
Phase 1 trial update evaluating everolimus in combination with rituximab and chemotherapy for newly diagnosed untreated diffuse large B-cell…
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CLINICAL_TRIALS research · 2017-07-28Clinical Trial Update: R-ACVBP and DA-EPOCH-R in Patients With Non-GCB DLBCL [Phase 3]
A Phase 3 clinical trial update examining two regimens, R-ACVBP and DA-EPOCH-R, in patients with non-GCB diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Thalidomide Maintenance Treatment in DLBCL [Phase 3]
Phase 3 clinical trial evaluating maintenance thalidomide in diffuse large B-cell lymphoma (DLBCL) is ongoing, with sponsor Nanfang Hospital…