Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-02-03Clinical Trial Update: Orelabrutinib With R-CHOP-like Regimen for Patients With Newly Diagnosed Untreated Non-GCB DLBCL [Phase 2]
Phase 2 trial evaluating orelabrutinib in combination with a R-CHOP-like regimen for newly diagnosed untreated non-GCB diffuse large B-cell …
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CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: Evaluation of Atezolizumab-Venetoclax-Obinutuzumab Combination in Relapse/Refractory Lymphomas [Phase 2]
Phase 2 clinical trial evaluating the atezolizumab-venetoclax-obinutuzumab combination in relapse/refractory lymphomas has completed enrollm…
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CLINICAL_TRIALS trial_result · 2022-12-29Clinical Trial Update: Lisocabtagene Maraleucel (JCAR017) as Second-Line Therapy (TRANSCEND-PILOT-017006) [Phase 2]
A Phase 2 trial update for lisocabtagene maraleucel (JCAR017) as second-line therapy in non-Hodgkin lymphoma has been completed with results…
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CLINICAL_TRIALS trial_result · 2022-12-23Clinical Trial Update: A Phase II Study of the FIL on Elderly Frail Patients With DLBCL [Phase 2]
Phase II study update of FIL in elderly frail patients with Diffuse Large B-Cell Lymphoma (DLBCL) completed.
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CLINICAL_TRIALS trial_result · 2022-12-08Clinical Trial Update: Pembrolizumab After ASCT for Hodgkin Lymphoma, DLBCL and T-NHL [Phase 2]
Phase 2 trial results for pembrolizumab after autologous stem cell transplant in Hodgkin lymphoma, diffuse large B-cell lymphoma, and periph…
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CLINICAL_TRIALS trial_result · 2022-12-05Clinical Trial Update: Reduced Chemotherapy in Low Risk DLBCL [Phase 4]
Phase 4 clinical trial update evaluating reduced chemotherapy in patients with diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2022-11-17Clinical Trial Update: Lenalidomide, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large Cell or Follicular B-Cell Lymphoma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated lenalidomide and rituximab in combination with chemotherapy for newly diagnosed diffuse large…
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CLINICAL_TRIALS trial_result · 2022-11-16Clinical Trial Update: Venetoclax Plus R-ICE Chemotherapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating venetoclax in combination with R-ICE chemotherapy for relapsed/refractory diffuse large B-cell lymphoma is active…
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CLINICAL_TRIALS trial_result · 2022-11-15Clinical Trial Update: Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 study assessing safety, pharmacokinetics, and efficacy of oral CC-223 in advanced solid tumors, non-Hodgkin lymphoma, or multiple …
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 study of polatuzumab vedotin in combination with rituximab or obinutuzumab plus bendamustine in relapsed/refractory follicular lym…
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CLINICAL_TRIALS trial_result · 2022-11-07Clinical Trial Update: Rituximab, Cyclophosphamide, Vincristine and Prednisone (R-CHOP) Plus Metformin in Diffuse Large-B-cell Lymphoma [Phase 2]
Phase 2 trial evaluating R-CHOP plus metformin in diffuse large B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Rituximab Plus CHOP Chemotherapy for Diffuse Large B-cell Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating Rituximab plus CHOP chemotherapy for diffuse large B-cell lymphoma (DLBCL), including people with HIV, h…
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Treatment for Advanced B-Cell Lymphoma [Phase 2]
Phase 2 clinical trial completed for treatment of advanced B-cell lymphoma, including diffuse large B-cell lymphoma and Burkitt's lymphoma.
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Mitoxantrone and Clofarabine for Treatment of Recurrent NHL or Acute Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating mitoxantrone with clofarabine for recurrent non-Hodgkin lymphoma or acute leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: Mitoxantrone Hydrochloride Liposome Combined With Rituximab and Lenalidomide (M+R2) in Patients With Relapsed and Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating mitoxantrone hydrochloride liposome plus rituximab and lenalidomide (M+R2) in relapsed/refractory diffus…
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CLINICAL_TRIALS trial_result · 2022-10-06Clinical Trial Update: Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas [Phase 2]
Phase II trial evaluating alemtuzumab with DA-EPOCH-R in relapsed or refractory Hodgkin lymphoma and diffuse large B-cell lymphoma has compl…
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CLINICAL_TRIALS trial_result · 2022-09-19Clinical Trial Update: Acalabrutinib in Combination With R-ICE For Relapsed or Refractory Lymphoma [Phase 2]
Phase 2 trial evaluating acalabrutinib in combination with the R-ICE chemotherapy regimen for relapsed or refractory lymphoma; the study was…
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CLINICAL_TRIALS trial_result · 2022-09-16Clinical Trial Update: Zanubrutinib Plus R-CHOP for Patients With Newly Diagnosed Untreated Non-GCB DLBCL [Phase 2]
Phase 2 trial update investigating zanubrutinib in combination with R-CHOP for newly diagnosed untreated non-GCB/ABC diffuse large B-cell ly…
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CLINICAL_TRIALS trial_result · 2022-09-13Clinical Trial Update: Phase 2 Study of AT13387 (Onalespib) in ALK+ ALCL, MCL, and BCL-6+ DLBCL [Phase 2]
Phase 2 study of AT13387 (Onalespib) in ALK+ anaplastic large cell lymphoma, mantle cell lymphoma, and BCL-6+ diffuse large B-cell lymphoma …
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CLINICAL_TRIALS trial_result · 2022-08-26Clinical Trial Update: Prephase Treatment With Prednisone +/- Vitamin D Supplementation Followed by Immunochemotherapy [Phase 3]
Phase 3 trial evaluating prephase prednisone +/- vitamin D before immunochemotherapy in elderly patients with diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2022-08-26Clinical Trial Update: B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021 [Phase 4]
Phase 4 clinical trial update for a B-cell mature non-Hodgkin lymphoma treatment protocol in children and adolescents; currently recruiting.
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CLINICAL_TRIALS trial_result · 2022-08-24Clinical Trial Update: JCAR014 and Durvalumab in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma [Phase 1]
Phase 1 trial evaluating JCAR014 in combination with Durvalumab for relapsed or refractory B-cell non-Hodgkin lymphoma has been terminated; …
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CLINICAL_TRIALS trial_result · 2022-08-19Clinical Trial Update: SPEL as Introductive Treatment Following Immune-chemotherapy as Consolidated Therapy for R/R DLBCL With p53 and/or c-Myc Expression [Phase 1, Phase 2]
A Phase 1/2 trial evaluating SPEL as introductory treatment following immunochemotherapy for relapsed/refractory diffuse large B-cell lympho…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Safety, PD & Efficacy of MT-3724 for the Treatment of Patients With Relapsed or Refractory DLBCL [Phase 1, Phase 2]
Phase 1/2 trial of MT-3724 in relapsed or refractory diffuse large B-cell lymphoma and related B-cell hematologic malignancies; the study is…
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CLINICAL_TRIALS trial_result · 2022-08-16Clinical Trial Update: PK,PD,Safety and Tolerability of Multiple Dose Regimens of MT-3724 With Gemcitabine and Oxaliplatin for the Treatment of Patients With Relapsed/Refractory Diffuse Large B Cell Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 trial evaluating multiple dose regimens of MT-3724 with gemcitabine and oxaliplatin in relapsed/refractory diffuse large B-cell lymp…