Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Connect® Lymphoma Disease Registry: A US-Based Prospective Observational Cohort Study
A US-based observational lymphoma registry sponsored by Celgene has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Multidisciplinary Care Program to Secure MEdication Therapy for HematoLOgy Patients Receiving Injectable Anticancer Drugs
A completed clinical trial evaluating a multidisciplinary care program to ensure medication therapy for hematology patients receiving inject…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: The Incidence of Hepatitis B in Diffuse Large B-Cell Lymphoma/Chronic Lymphoid Leukemia HBsAg-positive Treated With Rituximab, Chemotherapy and Tenofovir Alafenamide [Phase 2]
A Phase 2 trial evaluating the incidence of hepatitis B in HBsAg-positive patients with diffuse large B-cell lymphoma or chronic lymphocytic…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma [Phase 2, Phase 3]
A Phase 2/3 clinical trial of NKTR-255 after CD19-directed CAR-T therapy in relapsed/refractory large B-cell lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer [Phase 1]
Seagen's SEA-TGT (SGN-TGT) Phase 1 safety study in advanced cancers has been terminated. The study enrolled patients across multiple cancer …
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: A Study of Evaluating the Safety and Efficacy of ATG-010 in Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial evaluating ATG-010 for safety and efficacy in relapsed/refractory diffuse large B-cell lymphoma has completed, with results po…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: ME-401 and R-CHOP in Newly Diagnosed Diffuse Large B-Cell Lymphoma [Phase 1, Phase 2]
The Phase 1/2 study of ME-401 in combination with R-CHOP for newly diagnosed Diffuse Large B-Cell Lymphoma was terminated, with results post…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: A Study of Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
This Phase 2 trial evaluating Loncastuximab Tesirine in combination with Rituximab (Lonca-R) for previously untreated unfit/frail patients w…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma [Phase 1]
A Phase 1 trial evaluating the combination of chemotherapy with TAK-659 as front-line treatment for high-risk diffuse large B-cell lymphoma,…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma [Phase 2]
Phase 2 study evaluating anakinra to reduce CAR-T–related toxicity in patients with relapsed or refractory diffuse large B-cell lymphoma has…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Study to Assess Enzastaurin + R-CHOP in Subjects With DLBCL With the Genomic Biomarker DGM1™ [Phase 3]
Phase 3 trial evaluating enzastaurin added to R-CHOP in subjects with Diffuse Large B-Cell Lymphoma and the DGM1 genomic biomarker has compl…
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: Duvelisib Exposure to Enhance Immune Profiles of T Cells in Patients With Recurrent or Refractory Diffuse Large B-Cell Lymphoma, DEEP T CELLS Study [EARLY_Phase 1]
An early-phase study evaluating whether exposing T cells to the PI3K inhibitor duvelisib can enhance immune profiles in patients with recurr…
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: Understanding the Role of Large Extracellular Vesicles in Lymphomas and Lymphoproliferative Disorders: the "Off the Beaten Track" Liquid Biopsy
A completed clinical trial investigated the role of large extracellular vesicles as biomarkers in various lymphomas and lymphoproliferative …
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: A Study of Glofitamab in Combination With Rituximab or Obinutuzumab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP), or Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (CHP) in Participants With Non-Hodgkin Lymphomas or With DLBCL [Phase 1]
Phase 1 study evaluating glofitamab in combination with either rituximab or obinutuzumab plus CHOP, or polatuzumab vedotin plus rituximab wi…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: AZA Combined with R-GemOx for Elderly DLBCL Patients [Phase 2]
This Phase 2 trial evaluates azacitidine plus rituximab-gemcitabine-oxaliplatin (R-GemOx) in elderly patients with diffuse large B-cell lymp…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Comparison of Whole-body MRI, Circulating DNA and PET-CT in Staging, Prognosis, and Treatment Response in Patients with Diffuse Large Cell B Lymphoma
A completed clinical trial evaluating whole-body MRI, circulating DNA, and PET-CT for staging, prognosis, and treatment response in patients…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Sepantronium Bromide for the Treatment of High-grade B-cell Lymphoma [Phase 2]
A Phase 2 clinical trial update indicates Sepantronium bromide is being studied for high-grade B-cell lymphomas, with the study currently ac…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: OPTIMAL>60 / DR. CHOP, Improvement of Therapy of Elderly Patients with CD20+ DLBCL Using Rituximab Optimized and Liposomal Vincristine [Phase 3]
A Phase 3 trial evaluating rituximab-optimized therapy with liposomal vincristine for elderly patients with CD20+ diffuse large B-cell lymph…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas [Phase 2]
A Phase 2 study evaluating the triple combination therapy DTRM-555 in relapsed/refractory chronic lymphocytic leukemia and relapsed/refracto…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors [Phase 1, Phase 2]
An update on the Phase 1/2 study of CYT-0851 in B-cell malignancies and advanced solid tumors, noting completion of Phase 1/2 cohorts.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Ibrutinib, Bortezomib and Rituximab-CHOP for the Treatment of Elderly Patients With CD20+ DLBCL, IPI ≥ 2 [Phase 1, Phase 2]
This completed Phase 1/2 trial evaluated the combination of ibrutinib, bortezomib, and Rituximab-CHOP in elderly patients with CD20+ Diffuse…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL [Phase 1]
Phase 1 trial update evaluating safety, PK/PD, and clinical activity of KT-413 in adults with relapsed or refractory B-cell non-Hodgkin lymp…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Early Evaluation of the Response of Large B Cell Non Hodgkin's Lymphoma to Chemotherapy by PET/CT [NA]
A completed clinical trial update reporting on early PET/CT-based assessment of chemotherapy response in diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: RadiothErapy priMIng for CAR-T [NA]
Radiotherapy priming for CAR-T therapy in diffuse large B cell lymphoma is listed as an active but not recruiting trial. The entry appears t…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Pembrolizumab in Combination With R-ICE Chemotherapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab plus R-ICE chemotherapy as salvage therapy for relapsed/refractory diffuse large B-cell lymp…