Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma [Phase 3]
A Phase 3 trial evaluating combination chemotherapy for pediatric patients with advanced-stage large cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2014-07-23Clinical Trial Update: Provide Initial Evidence of Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy to Support the Pivotal CT-P10 Therapeutic Equivalence Trial [Phase 1]
This report provides Phase 1 safety, pharmacokinetics/pharmacodynamics, and preliminary efficacy data for CT-P10 (rituximab biosimilar) in d…
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CLINICAL_TRIALS trial_result · 2014-07-21Clinical Trial Update: Bortezomib, Doxorubicin Hydrochloride Liposome, and Rituximab in Treating Patients With Diffuse Large B-Cell Lymphoma That Has Relapsed or Not Responded to Treatment [Phase 2]
A Phase 2 trial tested a three-drug combination of bortezomib, liposomal doxorubicin, and rituximab in relapsed or refractory diffuse large …
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CLINICAL_TRIALS trial_result · 2014-07-10Clinical Trial Update: Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma [Phase 2]
This update notes the termination of the Phase 2 trial of MK-2206 in relapsed or refractory diffuse large B-cell lymphoma. No efficacy resul…
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: AZD1152 in Diffuse Large B-cell Lymphoma [Phase 1, Phase 2]
Update on Phase 1/2 clinical trials of AZD1152 (barasertib) in diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2014-07-01Clinical Trial Update: Imexon for Relapsed Follicular and Aggressive Lymphomas [Phase 2]
Phase 2 clinical trial results for imexon in relapsed follicular lymphoma and various aggressive B-cell lymphomas have been completed with r…
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CLINICAL_TRIALS trial_result · 2014-06-17Clinical Trial Update: Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 study evaluating vorinostat with or without isotretinoin in pediatric patients with recurrent or refractory solid tumors, lymphoma, …
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer [Phase 3]
Phase 3 trial evaluating total-body irradiation with or without fludarabine phosphate followed by donor stem cell transplant in hematologic …
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Patients With Relapsed or Refractory Diffuse Large B Cell Non Hodgkin Lymphomas [Phase 2]
This is a Phase 2 clinical trial update for relapsed or refractory diffuse large B-cell non-Hodgkin lymphoma that has been terminated with r…
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 trial evaluating obatoclax mesylate in combination with vincristine, doxorubicin, and dexrazoxane in pediatric patients with relapse…
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CLINICAL_TRIALS trial_result · 2014-04-29Clinical Trial Update: MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia [Phase 1]
Phase 1 study of MK-2206 in pediatric patients with recurrent or refractory solid tumors or leukemias has completed.
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Phase 1b Lymphoma Study of AMG 655 in Combination With Bortezomib or Vorinostat [Phase 1]
This is a Phase 1b trial update of AMG 655 in combination with bortezomib or vorinostat for lymphomas, including Hodgkin lymphoma and variou…
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Ixabepilone in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma [Phase 2]
This update reports results from a Phase 2 trial of ixabepilone in relapsed or refractory aggressive non-Hodgkin lymphoma across multiple su…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Rituximab and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 trial evaluating rituximab with combination chemotherapy in stage II-IV diffuse large B-cell non-Hodgkin's lymphoma has completed wi…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Tanespimycin and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas [Phase 1]
Phase 1 trial evaluating the combination of tanespimycin and bortezomib in adults with advanced solid tumors or lymphomas; the study was ter…
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating CCI-779 (temsirolimus) in patients with recurrent or refractory B-cell non-Hodgkin lymphoma or chronic l…
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: Radiolabeled Monoclonal Antibody in Treating Patients With Previously Treated Large Cell Lymphoma [Phase 1]
A Phase 1 clinical trial of a radiolabeled monoclonal antibody for patients with previously treated large cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: GM-CSF With or Without Vaccine Therapy After Combination Chemotherapy and Rituximab as First-Line Therapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma [Phase 3]
Phase 3 trial evaluating GM-CSF with or without a Favrille vaccine after first-line chemotherapy and rituximab in diffuse large B-cell lymph…
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CLINICAL_TRIALS trial_result · 2013-12-16Clinical Trial Update: Geldanamycin Analogue in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma [Phase 1]
Phase 1 trial of a geldanamycin analogue in patients with advanced solid tumors or Non-Hodgkin lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: Sunitinib in Treating Patients With Relapsed or Refractory Diffuse or Mediastinal Large B-Cell Lymphoma [Phase 2]
This Phase 2 trial assessed the use of sunitinib in adults with relapsed or refractory diffuse large B-cell lymphoma, including mediastinal …
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Study of the Combination of VELCADE, Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Non-Germinal Center B-Cell Subtype of Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 study evaluating two Velcade-based regimens with Rituximab and chemotherapy (cyclophosphamide, doxorubicin, prednisone) or with vinc…
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CLINICAL_TRIALS trial_result · 2013-10-30Clinical Trial Update: Early Treatment Stratification Based on PET Scan Response to Chemotherapy in Patients With Diffuse Large B-cell Lymphoma [Phase 2]
This Phase 2 clinical trial update describes using PET scan response to guide early treatment decisions in patients with diffuse large B-cel…
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CLINICAL_TRIALS trial_result · 2013-10-22Clinical Trial Update: A Double-blind, Randomized Controlled Study in CD20-positive Diffuse B Cell Non-Hodgkin's Lymphoma Subjects [Phase 1]
A Phase 1, double-blind, randomized controlled study in CD20-positive diffuse large B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating combination chemotherapy with rituximab in children with recurrent or refractory B-cell non-Hodgkin lymphoma or acu…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma [Phase 1]
Phase 1 trial evaluating Triapine (3-AP) in combination with gemcitabine in patients with advanced solid tumors or lymphoma has completed. I…