Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Obatoclax and Bortezomib in Treating Patients With Aggressive Relapsed or Recurrent Non-Hodgkin Lymphoma [Phase 1]
Phase 1 trial of obatoclax with bortezomib in adults with aggressive relapsed or recurrent non-Hodgkin lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: Lenalidomide And Rituximab as Maintenance Therapy in Treating Patients With B-Cell Non-Hodgkin Lymphoma [Phase 1]
Phase 1 trial of lenalidomide plus rituximab as maintenance therapy for adult B-cell non-Hodgkin lymphoma is noted as terminated.
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Study of Repeat Intranodal Injections of Ad-ISF35 [Phase 2]
Phase 2 study of repeat intranodal injections of Ad-ISF35 in various non-Hodgkin lymphomas was terminated; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-11-13Clinical Trial Update: Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a triple regimen of vorinostat, tacrolimus, and methotrexate to prevent graft-versus-host disease after allogeneic …
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: Study of YM155 in Refractory Diffuse Large B-cell Lymphoma (DLBCL) Subjects [Phase 2]
Phase 2 trial of YM-155 for refractory diffuse large B-cell lymphoma was terminated.
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 trial evaluating sorafenib tosylate in patients with recurrent aggressive non-Hodgkin lymphomas has completed, with results posted i…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Rituximab, Gemcitabine and Oxaliplatin (R-GEMOX) for Refractory/Relapsed B-cell Lymphoma [Phase 2]
Phase 2 trial results for R-GEMOX (rituximab, gemcitabine, oxaliplatin) in refractory/relapsed B-cell lymphoma, including diffuse large B-ce…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: R-CHOP-14 Versus R-CHOP-21 and Darbepoetin Alpha in Patients Aged 60-80 Years With Diffuse Large B-cell Lymphoma [Phase 3]
Phase 3 trial comparing R-CHOP-14 versus R-CHOP-21 with Darbepoetin alfa in patients aged 60-80 with diffuse large B-cell lymphoma has compl…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: ACVBP Plus Rituximab in Patients Aged From 18 to 59 Years With High-risk Diffuse Large B-cell Lymphoma [Phase 2]
This update reports the completion of a Phase 2 trial evaluating ACVBP plus Rituximab in adults aged 18 to 59 with high-risk diffuse large B…
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1]
Phase 1 study evaluating the combination of methoxyamine and fludarabine phosphate in adults with relapsed or refractory hematologic maligna…
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Clinical Study With Blinatumomab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 clinical trial evaluating blinatumomab in relapsed/refractory diffuse large B-cell lymphoma has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery [Phase 1]
Phase 1 study sponsored by the National Cancer Institute evaluating dasatinib in patients with metastatic or unresectable solid tumors and l…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: MGCD0103 Administered in Combination With Azacitidine (Vidaza®) to Subjects With Relapsed or Refractory Hodgkin or Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 trial of MGCD0103 in combination with azacitidine (Vidaza) for relapsed or refractory Hodgkin lymphoma and non-Hodgkin lymphoma ha…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma [Phase 2]
A Phase 2 trial evaluating infusion of blood cells (lymphocytes) to stimulate the immune system for fighting leukemia/lymphoma was terminate…
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Interleukin-12 in Treating Patients With Previously Treated Non-Hodgkin's Lymphoma or Hodgkin's Disease [Phase 2]
Phase 2 trial update reporting completion of a study evaluating interleukin-12 in patients with various previously treated non-Hodgkin lymph…
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Monoclonal Antibody Therapy and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial evaluating monoclonal antibody therapy with combination chemotherapy in advanced diffuse large B-cell lymphoma (DLBCL).
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER) [Phase 2]
Phase 2 GATHER trial evaluating obinutuzumab in combination with CHOP for previously untreated advanced diffuse large B-cell lymphoma; the s…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers [Phase 1]
First-in-human Phase 1 trial assessing safety, tolerability, and preliminary efficacy of an anti-CXCR4 antibody in acute myeloid leukemia an…
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: Prospective Cohort Study With Central Nervous System Evaluation in Diffuse Large B-cell Lymphoma [NA]
A completed prospective cohort study evaluating central nervous system involvement in diffuse large B-cell lymphoma was reported, sponsored …
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: A Randomized Phase IIb Placebo-Controlled Study of R-ICE Chemotherapy With and Without SGN-40 for Patients With DLBCL [Phase 2]
A Phase IIb randomized trial evaluating R-ICE chemotherapy with and without SGN-40 for diffuse large B-cell lymphoma/non-Hodgkin lymphoma ha…
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Feasibility Study of a 60 Minute Rapid Infusion Rituximab Protocol in Patients With B-cell Malignancies [Phase 2]
A Phase 2 feasibility study evaluating a 60-minute rapid infusion rituximab protocol in patients with indolent or intermediate-grade B-cell …
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CLINICAL_TRIALS trial_result · 2015-02-18Clinical Trial Update: Rituximab, Combination Chemotherapy, and 90-Yttrium Ibritumomab Tiuxetan for Patients With Stage I or II Non-Hodgkin's Lymphoma [Phase 2]
A Phase 2 trial evaluating Rituximab with chemotherapy and 90-yttrium ibritumomab tiuxetan in patients with Stage I or II non-Hodgkin lympho…
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies [Phase 1]
A Phase 1 pilot study evaluated co-infusing ex vivo expanded cord blood cells with an unmanipulated cord blood unit in patients undergoing c…
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CLINICAL_TRIALS trial_result · 2015-01-30Clinical Trial Update: The Response Study of Yt90-Zevalin in Patients With Diffuse Large B-cell Lymphoma After 6 Cycles of CHOP [Phase 2]
A Phase 2 trial update evaluating Yttrium-90 Zevalin in patients with Diffuse Large B-cell Lymphoma after 6 cycles of CHOP has been complete…
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: Study of SGN-40 in Patients With Relapsed Diffuse Large B-Cell Lymphoma [Phase 2]
A completed Phase 2 trial evaluating SGN-40 (dacetuzumab) in patients with relapsed diffuse large B-cell lymphoma and other non-Hodgkin lymp…