Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell Lymphoma [Phase 2]
A Phase 2 clinical trial update on the STORM regimen (temsirolimus, rituximab, and DHAP) for relapsed or refractory diffuse large B-cell lym…
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update on CD19-targeted CAR-T cell therapy being tested in relapsed/refractory leukemias and lymphomas (Phase 1 and Phase 2).
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 trial of Brentuximab Vedotin in relapsed or refractory non-Hodgkin lymphoma has completed and results have been posted. The study …
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CLINICAL_TRIALS trial_result · 2016-10-05Clinical Trial Update: Safety of Ibritumomab Tiuxetan (Zevalin®) in Combination With a Fludarabine-based Reduced Intensity Conditioning (RIC) Regimen (ZEVALLO 2007) [Phase 2]
This is a Phase 2 safety evaluation of combining ibritumomab tiuxetan (Zevalin) with a fludarabine-based reduced-intensity conditioning regi…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: the Sequential Therapy of CD19-targeted and CD20-targeted CAR-T Cell Therapy for Diffuse Large B Cell Lymphoma(DLBCL) [Phase 1, Phase 2]
The study evaluates sequential administration of CD19-targeted and CD20-targeted CAR-T cell therapy in patients with diffuse large B-cell ly…
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CLINICAL_TRIALS trial_result · 2016-08-29Clinical Trial Update: A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin's Lymphoma Grades 1, 2 or 3a [Phase 3]
Phase 3 trial comparing subcutaneous versus intravenous Rituxan in CD20+ diffuse large B-cell lymphoma and CD20+ follicular non-Hodgkin's ly…
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update for PCAR-019 evaluating efficacy and safety in CD19-positive relapsed or refractory leukemia and lymphoma across Phase…
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) [Phase 2]
Phase 2 trial of an epigenetic modulation approach in relapsed/refractory Diffuse Large B-Cell Lymphoma was terminated; results were posted …
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CLINICAL_TRIALS trial_result · 2016-05-26Clinical Trial Update: A Multicentre, Randomized Phase III Study of Rituximab as Maintenance Treatment Versus Observation in Patients With Aggressive B-cell Lymphoma: NHL-13 [Phase 3]
This update reports the completion of a multicentre, randomized Phase III trial evaluating rituximab as maintenance therapy versus observati…
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: Phase Ib/II Study of the Efficacy and Safety of the R-CMC544/R-GEMOX Combination in Diffuse Lage B-cell Lymphoma at First or Second Relapse [Phase 1, Phase 2]
This completed Phase Ib/II trial evaluated the efficacy and safety of the R-CMC544/R-GEMOX combination in patients with diffuse large B-cell…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: A Study Comparing the Efficiency and Safety of S-CHOP(Cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated CD20(Cluster of Differentiation Antigen 20)-Positive DLBCL Patients [Phase 3]
Phase 3 clinical trial comparing S-CHOP to R-CHOP in untreated CD20-positive diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Bendamustine Plus Subcutaneous Rituximab in Patients With Diffuse Large B-cell Lymphoma [Phase 2]
Phase 2 clinical trial update evaluating bendamustine with subcutaneous rituximab in patients with diffuse large B-cell lymphoma; the study …
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CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: A Study of Obinutuzumab in Chinese Participants With CD20+ Malignant Disease [Phase 1]
Phase 1 trial results for obinutuzumab in Chinese participants with CD20+ malignant disease. Diseases studied include chronic lymphocytic le…
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Bendamustine Combined With Rituximab for Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating the combination of bendamustine and rituximab for relapsed or refractory diffuse large B-cell lymphoma h…
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Prognostic Value of Clinical and Biological Factors in Patients With Refractory/Relapsed Diffuse Large B-cell Lymphoma
This completed study analyzes prognostic factors (clinical and biological) in patients with refractory or relapsed diffuse large B-cell lymp…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: A Randomised Evaluation of Molecular Guided Therapy for Diffuse Large B-cell Lymphoma With Bortezomib [Phase 3]
Phase 3 clinical trial updating the evaluation of molecular-guided therapy for diffuse large B-cell lymphoma with Bortezomib has completed.
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Lenalidomide With or Without Rituximab After Standard Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma [Phase 2]
Phase 2 trial evaluating lenalidomide with or without rituximab after standard chemotherapy in patients with diffuse large B-cell lymphoma; …
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CLINICAL_TRIALS trial_result · 2016-03-23Clinical Trial Update: Study of Ofatumomab in Combination With ICE-chemotherapy in Patients With Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 study evaluating the anti-CD20 antibody ofatumumab in combination with ICE chemotherapy for diffuse large B-cell lymphoma has comple…
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: MabThera (Rituximab) in Combination With CHOP (or CHOP-like) Chemotherapy in Patients With Aggressive B-Cell Lymphoma
This ClinicalTrials.gov entry notes completion and posting of results for a trial evaluating rituximab in combination with CHOP or CHOP-like…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: Transplantation With Ybritumomab Tiuxetan (Zevalin) Plus BEAM Regimen in Patients With Refractory Large B-cell Difusse Lymphom [Phase 2]
A Phase 2 study evaluating transplantation using Zevalin (ibritumomab tiuxetan) with BEAM conditioning in patients with refractory diffuse l…
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CLINICAL_TRIALS trial_result · 2016-02-12Clinical Trial Update: A Study of Subcutaneous Versus Intravenous MabThera/Rituxan (Rituximab) in Combination With CHOP Chemotherapy in Patients With Previously Untreated CD20-Positive Diffuse Large B-Cell Lymphoma [Phase 3]
Phase 3 study comparing subcutaneous versus intravenous rituximab added to CHOP in previously untreated CD20-positive diffuse large B-cell l…
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CLINICAL_TRIALS trial_result · 2016-02-03Clinical Trial Update: Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma [Phase 2]
A Phase 2 trial of selumetinib for relapsed or refractory diffuse large B-cell lymphoma has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2016-01-08Clinical Trial Update: MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma [Phase 1]
Phase 1 trial update for MORAb-004 in young patients with recurrent or refractory solid tumors or lymphoma; the study has been completed.
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: Efficacy of Consolidative Involved-site Radiotherapy for Patients With Limited-stage Diffuse Large B-cell Lymphoma [Phase 3]
Phase 3 clinical trial evaluating consolidative involved-site radiotherapy for patients with limited-stage diffuse large B-cell lymphoma; st…
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: The Palliative Benefit of Involved-site Radiotherapy for Patients With Advanced-stage Diffuse Large B-cell Lymphoma [Phase 3]
This document provides an update on a Phase 3 clinical trial evaluating the palliative benefit of involved-site radiotherapy for patients wi…