Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Phase I/II Trial of R-CHOP + Azacytidine in Diffuse Large B Cell Lymphoma [Phase 1, Phase 2]
Phase I/II study evaluating the addition of azacitidine to R-CHOP in patients with diffuse large B-cell lymphoma has completed with results …
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Study of 5-azacitidine in Combination With Vorinostat in Patients With Relapsed or Refractory Diffuse Large b Cell Lymphoma (DLBCL) [Phase 1, Phase 2]
This update describes results from a Phase 1/2 study of azacitidine in combination with vorinostat for relapsed or refractory diffuse large …
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Phase II Study of "VIPER" Chemotherapy in Rel/Ref DLBCL [Phase 2]
Phase II trial results for the VIPER chemotherapy regimen in relapsed/refractory diffuse large B-cell lymphoma (a form of non-Hodgkin lympho…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Akt Inhibitor MK2206 in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial of MK2206, an Akt inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma has completed with results …
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Phase I/II Trial of VELCADE + CHOP-Rituximab in Untreated DLCBL or Mantle Cell NHL [Phase 1, Phase 2]
Phase I/II study evaluating Velcade (bortezomib) added to CHOP-Rituximab in untreated diffuse large B-cell lymphoma and mantle cell lymphoma…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: An Investigational Drug Study With Suberoylanilide Hydroxamic Acid in Relapsed Diffuse Large B-cell Lymphoma (0683-013) [Phase 2]
Phase 2 trial of vorinostat (suberoylanilide hydroxamic acid) for relapsed diffuse large B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Panobinostat With Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma [Phase 2]
A Phase 2 trial evaluating panobinostat in combination with rituximab for relapsed/refractory diffuse large B-cell lymphoma was terminated, …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [NA]
A terminated clinical trial evaluated mobilizing donor peripheral blood stem cells with plerixafor and filgrastim before donor transplant in…
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Phase II Study About Combination CHOP-21, Obinutuzumab and Ibrutinib in Untreated Young High Risk DLBCL Patients. [Phase 2]
Phase II trial evaluating CHOP-21 with Obinutuzumab and Ibrutinib in untreated young high‑risk diffuse large B-cell lymphoma; the study stat…
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: Phase II Study of Vismodegib in Patients With Refractory or Relapsed B-cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
Phase II study of vismodegib in refractory or relapsed B-cell lymphoma or chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: ACVBP Versus ACVBP Plus Rituximab in Low Risk Localized Diffuse Large B-cell Lymphoma [Phase 3]
A Phase 3 trial comparing ACVBP alone versus ACVBP plus Rituximab in low-risk localized diffuse large B-cell lymphoma was terminated.
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Anti-CD22 CAR-T Therapy for CD19-refractory or Resistant Lymphoma Patients [Phase 1]
Phase 1 clinical trial update of an anti-CD22 CAR-T therapy for CD19-refractory or resistant lymphomas, including diffuse large B-cell lymph…
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Tandem Auto-Allo Transplant for Lymphoma [Phase 2]
Phase 2 clinical trial update on tandem auto-allo transplantation for various lymphomas, with completed status and results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Phase 2 Study of Bexxar in Relapsed/Refractory DLCL [Phase 2]
Phase 2 trial of Bexxar (tositumomab) in relapsed or refractory diffuse large B-cell lymphoma has completed. Results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy [Phase 1]
Phase 1 trial evaluating CART19 therapy for B-cell hematologic malignancies including various lymphomas and leukemias that are refractory or…
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Safety and Efficacy Study of a BTK Inhibitor in Subjects With Relapsed or Refractory Diffuse Large B-cell Lymphoma [Phase 2]
Phase 2 safety and efficacy results were posted in 2017 for a Bruton tyrosine kinase (BTK) inhibitor in patients with relapsed or refractory…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant [Phase 1, Phase 2]
This update covers a phase 1/2 clinical trial evaluating CD19 CAR T cells for B-cell malignancies in patients after allogeneic transplantati…
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: AMG 319 Lymphoid Malignancy FIH [Phase 1]
First-in-human Phase 1 clinical trial update for AMG 319 in lymphoid malignancies, including chronic lymphocytic leukemia and various lympho…
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 clinical trial evaluating a conditioning regimen with Iodine-131 tositumomab plus etoposide and cyclophosphamide, followed by autolo…
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL) [Phase 2]
A Phase 2 trial evaluating metformin in combination with standard induction therapy for diffuse large B-cell lymphoma was terminated; result…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Study to Assess the Effectiveness of RCHOP With or Without VELCADE in Previously Untreated Non-Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma Patients [Phase 2]
Phase 2 study evaluating the addition of bortezomib (VELCADE) to RCHOP for previously untreated Non-Germinal B-Cell-like Diffuse Large B-Cel…
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CLINICAL_TRIALS trial_result · 2016-12-22Clinical Trial Update: A Phase II Study of Doxycycline in Relapsed NHL [Phase 2]
Phase II trial of doxycycline in relapsed non-Hodgkin lymphoma was terminated and results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: PCAR-119 Bridge Immunotherapy Prior to Stem Cell Transplant in Treating Patients With CD19 Positive Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update describing the evaluation of PCAR-119 Bridge Immunotherapy as a pre-transplant treatment for CD19-positive leukemias a…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: An Observational Study of MabThera/Rituxan (Rituximab) in Combination With CHOP Chemotherapy in First-Line in Patients With Diffuse Large B-Cell Lymphoma
An observational study of Rituximab in combination with CHOP as first-line therapy for diffuse large B-cell lymphoma was terminated.
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 study evaluating vorinostat with rituximab and chemotherapy for newly diagnosed diffuse large B-cell lymphoma across stages II-IV.