Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-09-28Clinical Trial Update: Safety and Efficacy of BKM120 in Relapsed and Refractory NHL [Phase 2]
Phase 2 trial updating safety and efficacy of BKM120 in relapsed/refractory non-Hodgkin lymphomas (diffuse large B-cell, mantle cell, and fo…
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: R-ICE and High-Dose Cyclophosphamide With PET/CT for Diffuse Large B-Cell Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 trial of R-ICE and high-dose cyclophosphamide with PET/CT for diffuse large B-cell non-Hodgkin's lymphoma was terminated; results ar…
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Efficacy/Safety Study of R-CHOP vs Bortezomib-R-CAP for Young Patients With Diffuse Large B-cell Lymphoma With Poor IPI. [Phase 2]
Phase 2 trial comparing R-CHOP to Bortezomib-R-CAP in young patients with diffuse large B-cell lymphoma and poor IPI; study completed.
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CLINICAL_TRIALS trial_result · 2018-09-14Clinical Trial Update: A Clinical Trial of Decitabine in Relapse and Refractory Diffuse Large B Cell Lymphoma [Phase 4]
Clinical trial update for decitabine in relapse and refractory diffuse large B cell lymphoma (Phase 4).
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Dasatinib (Sprycel) in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL) [Phase 2]
Phase 2 study evaluating safety and efficacy of dasatinib in relapsed or refractory diffuse large B-cell lymphoma; trial terminated with res…
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: Oblimersen Sodium & Combination Chemotherapy in Treating Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma [EARLY_Phase 1]
A Phase 1 study evaluating oblimersen sodium in combination with chemotherapy for newly diagnosed diffuse large B-cell lymphoma has been ter…
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: Phase II Study to Evaluate the Combination of Rituximab and DepoCyte® in the C5R Chemotherapy Protocol in Patients Between the Ages of 18 and 60 Years With Primary Cerebral Non-Hodgkin Lymphoma and Systemic Diffuse Large B-cell Lymphoma With Neuromeningeal Invasion at Diagnosis [Phase 2]
Phase II study evaluating the combination of Rituximab and DepoCyte in patients with primary cerebral non-Hodgkin lymphoma and systemic diff…
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: R-ACVBP Versus R-CHOP in Patients Aged 60-65 With Diffuse Large B-cell Lymphoma [Phase 3]
Phase 3 trial comparing R-ACVBP to R-CHOP in older adults with diffuse large B-cell lymphoma has terminated.
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: Study of R-ACVBP Regimen Supported by Pegfilgrastim in High-Risk Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial of R-ACVBP regimen with pegfilgrastim in high-risk, untreated CD20-positive diffuse large B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: Lenalidomide and R-CHOP in B-cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial updating the combination of lenalidomide with R-CHOP in various B-cell lymphomas; study completed.
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Clinical Trial of Mitoxantrone HCL Liposome Injection in Patients With Relapsed DLBCL and PT/NKCLs [Phase 2]
Phase 2 clinical trial update for mitoxantrone HCL liposome injection in relapsed diffuse large B-cell lymphoma and PT/NKCLs (per ClinicalTr…
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: Bortezomib and Vorinostat in Treating Patients With Recurrent Mantle Cell Lymphoma or Recurrent and/or Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial of bortezomib plus vorinostat in recurrent mantle cell lymphoma or recurrent/diffuse large B-cell lymphoma has completed with …
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CLINICAL_TRIALS trial_result · 2018-08-02Clinical Trial Update: Chidamide With R-CHOP Regimen for DLBCL Patients [Phase 2]
Phase 2 trial investigating chidamide with R-CHOP for diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: Two Different Methods of Collecting Stem Cells For an Autologous Stem Cell Transplant in Treating Patients With Diffuse Large Cell Lymphoma [Phase 3]
A Phase 3 trial comparing two stem cell collection methods for autologous stem cell transplant in patients with diffuse large B-cell lymphom…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma [Phase 1]
Phase 1 trial evaluating a triple regimen of devimistat (CPI-613), bendamustine hydrochloride, and rituximab in relapsed or refractory B-cel…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: An Efficacy and Safety Proof of Concept Study of Daratumumab in Relapsed/Refractory Mantle Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma [Phase 2]
A Phase 2 proof-of-concept study evaluated daratumumab in relapsed/refractory mantle cell lymphoma, diffuse large B-cell lymphoma, and folli…
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: Phase 1/2, Open-label, Dose-escalation Study of IONIS-STAT3Rx, Administered to Patients With Advanced Cancers [Phase 1, Phase 2]
Phase 1/2 open-label dose-escalation study of IONIS-STAT3Rx in patients with advanced cancers, including diffuse large B-cell lymphoma, has …
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Study of Brentuximab Vedotin Combined With RCHOP or RCHP in Front-line Treatment of Patients With Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 trial of brentuximab vedotin combined with RCHOP or RCHP in first-line diffuse large B-cell lymphoma was terminated; results were po…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas [Phase 1, Phase 2]
Clinical trial evaluating vorinostat in combination with chemotherapy and rituximab for HIV-related and other aggressive B-cell lymphomas; t…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Alisertib With and Without Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma [Phase 2]
Phase 2 study evaluating alisertib with or without rituximab in relapsed or refractory B-cell non-Hodgkin lymphomas was terminated; results …
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Early Response Assessment in Diffuse Large B-Cell Lymphoma (DLCL) Patients by 18-fluoro-2-deoxyglycose Positron Emission Tomography (FDG-PET)
This update reports that the clinical trial evaluating early response assessment in diffuse large B-cell lymphoma using FDG-PET has complete…
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CLINICAL_TRIALS trial_result · 2018-05-14Clinical Trial Update: Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT [Phase 2]
Phase 2 study in poor-risk diffuse large B-cell lymphoma using total lymphoid irradiation and anti-thymocyte globulin, followed by matched a…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patients [Phase 2]
Phase 2 trial evaluating a three-drug regimen (Tacrolimus, Bortezomib, and Thymoglobulin) to prevent low-toxicity graft-versus-host disease …
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CLINICAL_TRIALS trial_result · 2018-04-27Clinical Trial Update: Study of 90Y-DOTA-hLL2 as a Consolidation Therapy After R-CHOP in Patients With Diffuse Large B-cell Lymphoma [Phase 2]
The trial update reports termination of a Phase 2 study evaluating 90Y-DOTA-hLL2 as consolidation therapy after R-CHOP in patients with diff…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: Safety Study of SGN-CD70A in Cancer Patients [Phase 1]
A Phase 1 safety study of SGN-CD70A in renal cell carcinoma and several lymphomas has completed.