Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Study of VAY736 as Single Agent and in Combination With Select Antineoplastic Agents in Patients With Non-Hodgkin Lymphoma [Phase 1]
Phase 1 study update for VAY736 in non-Hodgkin lymphoma shows the trial status as terminated, evaluating VAY736 alone and in combination wit…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: DZD8586 Combination Therapy in Patients With Diffuse Large B-cell Lymphoma (TAI-SHAN12) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the combination therapy DZD8586 in patients with Diffuse Large B-Cell Lymphoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignancies [Phase 1]
Phase 1 trial evaluating autologous CD22 CAR T cells in adults with recurrent or refractory B-cell malignancies has completed enrollment. Re…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Romidepsin, Gemcitabine, Dexamethasone and Cisplatin in the Treatment of Peripheral T-Cell and Diffuse Large B-Cell Lymphoma [Phase 1]
Phase 1 trial evaluating a four-drug regimen (romidepsin, gemcitabine, dexamethasone, cisplatin) in peripheral T-cell lymphoma and diffuse l…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Axi-Cel as a 2nd Line Therapy in Patients With Relapsed/Refractory Aggressive B Lymphoma Ineligible to Autologous Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial evaluates axicabtagene ciloleucel as second-line therapy for relapsed/refractory aggressive B-cell lymphoma in pati…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib [Phase 2]
A Phase 2 trial evaluated the Bruton tyrosine kinase inhibitor zanubrutinib in CD79B-mutant relapsed/refractory diffuse large B-cell lymphom…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: IT-TT as an Effective and Well-Tolerated Strategy for CNS Prop in High-Risk DLBCL: a Prospective Ph II Study [Phase 2]
A Phase 2 prospective trial from Zhejiang Cancer Hospital reports that intrathecal TT (IT-TT) appears to be an effective and well-tolerated …
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Chidamide for Maintenance Treatment of HBV-infected Diffuse DLBCL in Patients Initially Treated With R-CHOP [Phase 3]
An ongoing Phase 3 trial evaluating chidamide as maintenance therapy for HBV-infected diffuse large B-cell lymphoma after R-CHOP is currentl…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Maintenance Therapy of Chidamide in Patients With HBV Positive Diffuse Large B-cell Lymphoma [Phase 2]
Phase 2 trial evaluating maintenance therapy with chidamide in HBV-positive Diffuse Large B-cell Lymphoma has completed. The study assessed …
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A Phase 1/2 study evaluating ALX148 in combination with Rituximab and Lenalidomide for various B-cell non-Hodgkin lymphomas, with the trial …
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Study of LY4152199 in Participants With Previously Treated B-cell Cancers (BAF_FRontier-1 ) [Phase 1]
A Phase 1 study of LY4152199 in previously treated B-cell cancers is listed, with the trial currently NOT_YET_RECRUITING.
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Efficacy and Safety of Glofitamab Combined With GemOxin the Treatment of Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
This clinical trial update reports on the efficacy and safety of combining glofitamab with GemOx (gemcitabine plus oxaliplatin) in patients …
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Treatment of Patients With Diffuse Large B Cell Lymphoma Who Are Not Suitable for Anthracycline Containing Chemotherapy [Phase 2]
Phase 2 clinical trial evaluating treatment for patients with diffuse large B-cell lymphoma who are not suitable for anthracycline-containin…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML [Phase 1]
Phase 1 trial update for voruciclib alone or with venetoclax in various B-cell malignancies and acute myeloid leukemia; the study has been t…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Treatment by a Bispecific CD3xCD20 Antibody for Relapse/Refractory Lymphomas After CAR T-cells Therapy [Phase 2]
Phase 2 clinical trial evaluating a CD3xCD20 bispecific antibody for relapse/refractory B-cell non-Hodgkin lymphomas after CAR-T therapy has…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Real-World Effectiveness and Safety of Glofitamab in Primary Refractory and Early Relapsed Diffuse Large B-Cell Lymphoma
This clinical trial update reports real-world effectiveness and safety of glofitamab in patients with primary refractory and early relapsed …
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas [Phase 1, Phase 2]
Phase 1/2 study evaluating the combination of lenalidomide with DA-EPOCH-R in MYC-associated B-cell lymphomas has completed, and results hav…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma [Phase 2]
This document reports on a Phase II clinical trial evaluating the combination of glofitamab with polatuzumab-R-CHP for high-risk diffuse lar…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2) [Phase 1, Phase 2]
Clinical Trial Update on the ALPHA2 Phase 1/2 study evaluating ALLO-501A anti-CD19 allogeneic CAR T cells in adults with relapsed/refractory…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: DZD8586 in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (TAI-SHAN9) [Phase 2]
Phase 2 trial TAi-SHAN9 evaluating DZD8586 in relapsed or refractory diffuse large B-cell lymphoma is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes
Clinical trial update reporting on neurocognitive effects and patient-reported outcomes for axicabtagene ciloleucel in diffuse large B-cell …
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Safety and Efficacy of ALLO-501 Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell or Follicular Lymphoma [Phase 1]
Phase 1 trial results show safety and preliminary efficacy for ALLO-501, an allogeneic anti-CD19 CAR-T therapy, in adults with relapsed/refr…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Rituximab and Pembrolizumab With or Without Lenalidomide in Treating Patients With Relapsed Follicular Lymphoma and Diffuse Large B-Cell Lymphoma [Phase 2]
This Phase 2 trial evaluates rituximab and pembrolizumab with or without lenalidomide in relapsed follicular lymphoma and diffuse large B-ce…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Anakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients With Recurrent or Refractory Large B-cell Lymphoma [Phase 2]
Phase 2 trial evaluating anakinra to prevent severe CAR-T cell-related encephalopathy in patients with recurrent or refractory diffuse large…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Study of BGB-10188 as Monotherapy, and in Combination With Zanubrutinib, and Tislelizumab [Phase 1, Phase 2]
BeiGene announced completion and posted results for a Phase 1/2 study of BGB-10188 as monotherapy and in combination with zanubrutinib and t…