Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: A Phase I Study of AC0010 in Patients With CLL/ SLL, MCL, DLBCL and Other NHL [Phase 1]
Phase I trial evaluating AC0010 in patients with CLL/SLL, mantle cell lymphoma, diffuse large B-cell lymphoma, and other non-Hodgkin lymphom…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Chidamide Combined With Clad/Gem/Bu With AutoSCT in R/R Diffuse Large B Cell Lymphoma [Phase 2]
Phase 2 trial evaluating chidamide in combination with cladribine, gemcitabine, and busulfan plus autologous stem cell transplantation for r…
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CLINICAL_TRIALS research · 2018-07-17Clinical Trial Update: An Observational Study on Evaluating the Efficacy and Safety of Preemptive Antiviral Therapy With Tenofovir in HBsAg-positive Patients With Diffuse Large B-cell Lymphoma Receiving Rituximab-CHOP Chemotherapy (SPEED Study)
An observational study sponsored by Yonsei University evaluating whether preemptive antiviral therapy with Tenofovir is effective and safe f…
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CLINICAL_TRIALS research · 2018-05-01Clinical Trial Update: Treatment of Elderly Patients With Diffuse Large B-cell Lymphoma [Phase 4]
Clinical trial update for a Phase 4 study on treating elderly patients with Diffuse Large B-Cell Lymphoma; the trial status is currently unk…
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CLINICAL_TRIALS research · 2018-04-11Clinical Trial Update: A Prospective Study of Low-dose Decitabine Combined With COP Regimen in the Treatment of Relapsed and Refractory DLBCL
This entry describes a prospective clinical trial evaluating low-dose decitabine combined with the COP chemotherapy regimen for relapsed and…
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CLINICAL_TRIALS research · 2018-04-10Clinical Trial Update: Assessment of Blood Biomarkers by DNA Microarrays in Patients With Aggressive Lymphoma BMS_LyTrans
This completed study investigates blood biomarkers in patients with diffuse large B-cell lymphoma using DNA microarray analysis.
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: Chidamide Plus R-CHOP in Elderly DLBCL [Phase 2]
This document notes a Phase 2 clinical trial evaluating chidamide in combination with R-CHOP for elderly patients with Diffuse large B-cell …
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: A Study of Bortezomib Plus GDP in the Treatment of Refractory and Relapsed Non-GCB DLBCL [Phase 2]
A Phase 2 study evaluating the addition of bortezomib to GDP (gemcitabine, dexamethasone, cisplatin) chemotherapy in patients with refractor…
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: R-CEOP-90/R-CEOP-70 Versus R-CHOP-50 in the Treatment of Diffuse Large B-cell Lymphoma and Follicular Lymphoma Grade 3B [Phase 3]
Phase 3 randomized trial comparing R-CEOP-90/70 versus R-CHOP-50 for Diffuse large B-cell lymphoma and Follicular lymphoma grade 3B; current…
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CLINICAL_TRIALS research · 2017-10-24Clinical Trial Update: Thalidomide Combined With R-CHOP in Newly Diagnosed，Untreated Double-expressor Diffuse Large B-Cell Lymphoma Patients [Phase 3]
A Phase 3 clinical trial is evaluating thalidomide in combination with R-CHOP for newly diagnosed, untreated double-expressor diffuse large …
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CLINICAL_TRIALS research · 2017-10-12Clinical Trial Update: BUCY+VP-16 vs BUCY Conditioning Regimen for DLBCL Undergoing Auto-HSCT [Phase 2, Phase 3]
This clinical trial update compares BUCY+VP-16 versus BUCY conditioning in patients with diffuse large B-cell lymphoma undergoing autologous…
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CLINICAL_TRIALS research · 2017-10-11Clinical Trial Update: Role of CX3CR1-expressing Cells in Hematologic Malignancy
A clinical trial update examining the role of CX3CR1-expressing cells in hematologic malignancies, including Diffuse Large B-Cell Lymphoma a…
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CLINICAL_TRIALS research · 2017-07-28Clinical Trial Update: R-ACVBP and DA-EPOCH-R in Patients With Non-GCB DLBCL [Phase 3]
A Phase 3 clinical trial update examining two regimens, R-ACVBP and DA-EPOCH-R, in patients with non-GCB diffuse large B-cell lymphoma.
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: Study of Safety,Efficacy and Pharmacokinetics of CT-1530 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's Macroglobulinemia [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of CT-1530 in relapsed or refractory B-cell non-Hodgkin lymphoma, chronic lymphocyt…
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CLINICAL_TRIALS research · 2017-07-17Clinical Trial Update: Cinobufacini Tablets Combined With Chemotherapeutic Protocol in Treatment of Diffuse Large B Cell Lymphoma [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating Cinobufacini tablets in combination with standard chemotherapy for diffuse large B-cell lymphoma; current…
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CLINICAL_TRIALS research · 2017-07-07Clinical Trial Update: Assessment of the Minimal Residual Disease in DLBCL From Cell-free Circulating DNA by NGS [NA]
Completed clinical trial evaluating minimal residual disease in diffuse large B-cell lymphoma using cell-free circulating DNA detected by ne…
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CLINICAL_TRIALS research · 2017-07-06Clinical Trial Update: Risk Adapted Therapy in Diffuse Large B Cell Lymphoma [Phase 2]
An update on a Phase 2 trial evaluating risk-adapted therapy for diffuse large B-cell lymphoma.
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CLINICAL_TRIALS research · 2017-05-19Clinical Trial Update: Study of Biomarkers Using Tissue Samples From Older Patients With Diffuse Large B-Cell Lymphoma Treated With Combination Chemotherapy With or Without Rituximab on Clinical Trial ECOG-E4494
This update reports on a biomarker study using tissue samples from older patients with diffuse large B-cell lymphoma treated with combinatio…
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: R±CEOP90 Versus R±CEOP75 in Newly Diagnosed Young Patients With Medium/High-risk DLBCL [Phase 3]
Phase 3 trial update comparing R±CEOP90 versus R±CEOP75 in newly diagnosed young patients with medium/high-risk diffuse large B-cell lymphom…
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CLINICAL_TRIALS research · 2017-05-02Clinical Trial Update: PD-1 Knockout EBV-CTLs for Advanced Stage Epstein-Barr Virus (EBV) Associated Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating PD-1 knockout EBV-specific cytotoxic T lymphocytes for advanced EBV-associated malignancies, includ…
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CLINICAL_TRIALS research · 2017-03-31Clinical Trial Update: The Value and Mechanisms for Monocytes Subpopulations in Predicting the Prognosis of Lymphomas
This clinical trial explores whether monocyte subpopulations can predict prognosis in lymphomas, including diffuse large B-cell lymphoma. It…
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CLINICAL_TRIALS research · 2017-03-27Clinical Trial Update: Effectiveness of Circulating DNA for Predicting the Relapse and Overall Survival in NHL Patients
The trial update examines circulating tumor DNA as a biomarker to predict relapse and overall survival in non-Hodgkin lymphoma patients, inc…
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CLINICAL_TRIALS research · 2017-03-23Clinical Trial Update: Study Evaluating the Efficacy and Safety With CAR-T for Recurrent or Refractory Diffuse Large B Cell Lymphoma [NA]
Clinical trial update on evaluating the efficacy and safety of CAR-T therapy for recurrent or refractory diffuse large B-cell lymphoma; the …
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CLINICAL_TRIALS research · 2017-03-16Clinical Trial Update: Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma [Phase 1, Phase 2]
This document describes a Phase 1/2 clinical trial evaluating competitive transfer of two αCD19-TCRz-CAR-T cell constructs (one with CD28 an…
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CLINICAL_TRIALS research · 2017-02-14Clinical Trial Update: RICE-ibrutinib in Relapsed DLBCL [Phase 2]
A Phase 2 trial evaluating the RICE-ibrutinib regimen in relapsed or recurrent diffuse large B-cell lymphoma; the current trial status is UN…