Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: A Retrospective Study on Extranodal DLBCL
A completed retrospective study examining extranodal diffuse large B-cell lymphoma is reported as an update from Ruijin Hospital.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Characterization and Clinical Impact of the Gut Microbiota in Lymphoma
This entry describes a clinical trial investigating how the gut microbiota may influence Diffuse large B-cell lymphoma and its clinical outc…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Phase I/IIa Study of BR1733 in Subjects With Advanced Cancers [Phase 1, Phase 2]
Phase I/IIa clinical trial update for BR1733 in advanced cancers, including follicular lymphoma, peripheral T-cell lymphoma, and diffuse lar…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: The Efficacy and Safety of Pola-ZR2 Versus ZR2 in the Treatment of Old Patients With de Novo Diffuse Large B-cell Lymphoma [Phase 3]
Phase 3 trial comparing Pola-ZR2 to ZR2 in older patients with de Novo Diffuse Large B-Cell Lymphoma; currently recruiting to evaluate effic…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study [Phase 2]
Open-phase 2 multicenter trial evaluating Milaberon in advanced solid tumors across multiple indications, currently recruiting.
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: Feasibility Study of Induction and Maintenance Avelumab Plus R-CHOP in Patients With Diffuse DLBCL: The AvR-CHOP Study [EARLY_Phase 1]
Feasibility early-phase trial evaluating induction and maintenance therapy with avelumab plus R-CHOP in patients with diffuse large B-cell l…
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR [Phase 1, Phase 2]
A Phase 1/2 clinical trial at University Hospital Heidelberg is evaluating third-generation CD19-directed CAR T cells in relapsed or refract…
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Molecular Mechanisms in Malignant Lymphoma- Predict (MMML Predict)
MMML Predict is a clinical trial exploring molecular mechanisms in malignant lymphoma, with recruitment ongoing for diffuse large B-cell lym…
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Evaluate the Safety and Efficacy of Tafasitamab and Lenalidomide in Combination With Gemcitabine and Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 3]
This is a Phase 3 trial evaluating tafasitamab plus lenalidomide with gemcitabine and oxaliplatin versus rituximab with gemcitabine and oxal…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: A Study Comparing the Efficacy and Safety of Pola-RCHP-X Versus RCHOP-X and Pola-RCHP in Previously Untreated Patients With DLBCL [Phase 2]
A Phase 2 trial compares Pola-RCHP-X against RCHOP-X and Pola-RCHP in previously untreated diffuse large B-cell lymphoma.
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL [Phase 2]
Phase 2 clinical trial evaluating salvage therapy that includes epcoritamab (Epcor) followed by autologous stem cell transplant and epcorita…
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Whole-body Diffusion-weighted Magnetic Resonance Imaging for Staging and Treatment Prediction of Lymphoma [NA]
This document provides an update on a clinical trial evaluating whole-body diffusion-weighted MRI for staging and predicting treatment respo…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: A-RGEMOX in the Treatment of Early Relapsed/Refractory DLBCL [Phase 2]
A Phase 2 clinical trial evaluating A-RGEMOX for early relapsed/refractory diffuse large B-cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis [Phase 2]
Phase 2 trial update describing biomarker-driven intensified chemo-immunotherapy with early CNS prophylaxis for diffuse large B-cell lymphom…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Polatuzumab Vedotin and Zanubrutinib Plus R-CHP for Patients With Newly Diagnosed Untreated Non-GCB DLBCL [Phase 2]
Phase 2 clinical trial evaluating polatuzumab vedotin and zanubrutinib plus R-CHP for newly diagnosed untreated diffuse large B-cell lymphom…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Selinexor Plus R-CHOP in High-risk GCB-subtype Diffuse Large B-Cell Lymphoma [Phase 2]
A Phase 2 clinical trial is evaluating the combination of selinexor with R-CHOP for high-risk germinal center B-cell subtype diffuse large B…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL [Phase 2]
Clinical trial evaluating the efficacy of Pola-RCHP-X versus Pola-RCHP in untreated diffuse large B-cell lymphoma (Phase 2; not yet recruiti…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment
A clinical trial investigating the role of the hematopoietic niche and inflammation in cytopenias after CAR-T cell therapy, exploring therap…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: BCL6-rearrangements Implications in Non-Hodgkin Lymphomas.
This clinical trial update discusses the implications of BCL6 rearrangements across non-Hodgkin lymphomas, including follicular lymphoma, ma…
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CLINICAL_TRIALS research · 2024-05-22Clinical Trial Update: Study to Evaluate the Effectiveness of Tafasitamab in Combination With Lenalidomide Followed by Tafasitamab Monotherapy in Relapsed or Refractory Diffuse Large B-cell Lymphoma Non-transplant Eligible Patients in Italy (PRO-MIND)
Clinical trial evaluating tafasitamab in combination with lenalidomide followed by tafasitamab monotherapy in relapsed or refractory diffuse…
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Zanubrutinib With R-CHOP in Newly Diagnosed Non-GCB DLBCL Patients With Double Expression [Phase 2]
A Phase 2 clinical trial evaluating the combination of zanubrutinib with the R-CHOP regimen in newly diagnosed non-GCB Diffuse Large B-Cell …
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma [Phase 1]
This Phase 1 trial investigates fludarabine and cyclophosphamide with or without rituximab as a lymphodepletion regimen before CD19 CAR-T ce…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Care Pathway and Associated Costs of Patients Treated With CAR T-cells Based on SNDS Data
This study updates care pathways and costs for patients treated with CAR T-cell therapies using SNDS data.
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CLINICAL_TRIALS research · 2021-07-22Clinical Trial Update: Tailoring Treatment for B Cell Non-hodgkin's Lymphoma Based on PET Scan Results Mid Treatment [Phase 2]
A Phase 2 clinical trial exploring tailoring treatment for advanced diffuse large B-cell non-Hodgkin lymphoma based on mid-treatment PET sca…
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CLINICAL_TRIALS research · 2021-05-18Clinical Trial Update: Detection and Quant of Differences in Hodgkin Lymphoma and Diffuse Large B-cell Lymphoma Using Positron Emission Tomography/Computed Tomography (PET/CT) [NA]
A completed clinical trial evaluating detection and quantification of differences in Hodgkin lymphoma and diffuse large B-cell lymphoma usin…