Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Glofitamab for Consolidation After First-line Treatment of High-risk Large B-cell Lymphoma [Phase 4]
This clinical trial update reports a Phase 4 study of glofitamab as consolidation after first-line therapy in patients with high-risk diffus…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies [Phase 1, Phase 2]
IDP-121 is being studied in a Phase 1/2 trial for relapsed/refractory hematologic malignancies and is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Axicabtagene Ciloleucel Injection as First-Line Therapy of High-Risk Large B-Cell Lymphoma [NA]
A clinical trial is evaluating axicabtagene ciloleucel as first-line therapy for high-risk diffuse large B-cell lymphoma, with recruitment n…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Radiation Dose Optimization in Diffuse Large B- Cell Lymphoma. [NA]
This clinical trial update notes recruitment for a study on optimizing radiation dose in diffuse large B-cell lymphoma, a form of non-Hodgki…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: A Study of R-mini-MCOP in the Treatment of Elderly, Previously Untreated DLBCL [Phase 2]
This entry describes a Phase 2 clinical trial evaluating R-mini-MCOP in elderly, previously untreated diffuse large B-cell lymphoma, which i…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Mixed Molecular Clinical Index (MMCI) in Diffuse Large B-cell Lymphoma (DLBCL)
A clinical trial is currently recruiting to evaluate the Mixed Molecular Clinical Index (MMCI) in patients with diffuse large B-cell lymphom…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Study to Evaluate Efficacy and Safety of Oral Abexinostat in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of oral abexinostat in patients with relapsed or refractory diffuse large B-cell l…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Study of Loncastuximab Tesirine in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) or High-Grade B-Cell Lymphoma (HGBCL) Following CAR-T Therapy Failure [Phase 2]
A Phase 2 clinical trial evaluating loncastuximab tesirine in patients with relapsed or refractory diffuse large B-cell lymphoma or high-gra…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies [Phase 1]
Phase 1 study evaluating autologous CD19 CAR-T cell therapy SYNCAR-001 with orthogonal IL-2 STK-009 in CD19-positive hematologic malignancie…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Safety and Efficacy of R-CMOP Versus R-CHOP in the Initial Treatment of DLBCL [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing R-CMOP versus R-CHOP as initial therapy for Diffuse Large B-Cell Lymphoma; the study is currently recru…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Safety and Efficacy of Early Second Infusion of Axi-cel Based on ctDNA for R/R Large B - Cell Lymphoma [Phase 1, Phase 2]
This clinical trial update assesses the safety and efficacy of an early second infusion of axicabtagene ciloleucel guided by ctDNA for relap…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Epcoritamab-CAR T Cells for Large B-cell Lymphomas [Phase 2]
Phase 2 clinical trial evaluating epcoritamab-CAR T cells for large B-cell lymphomas, currently recruiting.
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Zanubrutinib, Chidamide, and Rituximab Induction With or Without CHOP Versus R-CHOP in Newly Diagnosed Double-Expressor DLBCL [Phase 2]
Phase 2 trial evaluating induction with Zanubrutinib, Chidamide, and Rituximab with or without CHOP versus R-CHOP in newly diagnosed double-…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Clinical Trial of TQB2825 Injection Combined With Chemotherapy in Subjects With Diffuse Large B-cell Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating TQB2825 injection in combination with chemotherapy for diffuse large B-cell lymphoma is currently recrui…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Chidamide Plus R-CHOP in Newly Diagnosed Double-Expressor Diffuse Large B-Cell Lymphoma With Other Molecular Subtypes [Phase 2]
This Phase 2 clinical trial assesses chidamide in combination with R-CHOP for newly diagnosed double-expressor diffuse large B-cell lymphoma…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: CHiR Therapy for Elderly DLBCL Intolerant to Chemo [Phase 2]
Phase 2 clinical trial evaluating CHiR Therapy for elderly patients with diffuse large B-cell lymphoma intolerant to chemotherapy is current…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Clinical Study of HiR+X Therapy for Newly Diagnosed Elderly Patients With DLBCL Intolerant to Chemotherapy [Phase 2]
A Phase 2 clinical trial of HiR+X Therapy for newly diagnosed elderly patients with Diffuse Large B-Cell Lymphoma who are intolerant to chem…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Hypofractionation Radiotherapy in Combination with Glofitamab in Relapsed/refractory Diffuse B-cell Lymphoma with Baseline High Tumor Burden [Phase 2]
Phase 2 trial evaluating hypofractionated radiotherapy in combination with glofitamab for relapsed/refractory diffuse large B-cell lymphoma …
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Glofitamab Combination With Chidamide in Patients With Recurrent/Refractory DLBCL [Phase 2]
Phase 2 trial evaluating the combination of glofitamab and chidamide for recurrent or refractory diffuse large B-cell lymphoma is currently …
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1) [Phase 1, Phase 2]
CHAMP-1 is a Phase 1/2 study evaluating RNK05047 in adults with advanced solid tumors or diffuse large B-cell lymphoma, currently recruiting…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: CD70-targeted immunoPET Imaging of Malignant Cancers [NA]
A clinical trial evaluating CD70-targeted immunoPET imaging in multiple cancers is currently recruiting, including renal cell carcinoma, dif…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL [Phase 2]
A Phase 2 clinical trial evaluating lenalidomide in combination with G-CHOP for newly diagnosed diffuse large B-cell lymphoma with follicula…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: AZA Combined With RCHOP in P53-mutated DLBCL. [Phase 2]
Phase 2 clinical trial evaluating azacitidine in combination with the R-CHOP regimen for TP53-mutated diffuse large B-cell lymphoma, current…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: A Multicenter, Prospective, Real-world Study of a Regimen Containing Tucidinostat for Primary Treatment of DLBCL
A multicenter prospective real-world study evaluating a tucidinostat-containing regimen as first-line treatment for diffuse large B-cell lym…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Study of Pomalidomide Combination with Rituximab and Anti-PD-1 Antibody (PPR) in Third or Later Line Therapy of DLBCL [NA]
This clinical trial update describes a study of pomalidomide with rituximab and an anti-PD-1 antibody (PPR) for third- or later-line diffuse…