Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Large Fraction Radiation Therapy Combined With Lenalidomide, and Glofitamab in Refractory Relapsed DLBCL [Phase 2]
Phase 2 trial testing large fraction radiotherapy in combination with lenalidomide and glofitamab for relapsed/refractory diffuse large B-ce…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Study on Predicting Response to Standard First-Line Treatment in Diffuse Large B-Cell Lymphoma (DLBCL) Patients Using ctDNA Combined With PET
A clinical trial update from Fudan University shows recruiting to evaluate whether combining ctDNA analysis with PET can predict response to…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: A Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or Refractory Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma With Hepatic Impairment (LOTIS-10) [Phase 1]
Phase 1 LOTIS-10 study assessing the pharmacokinetics and safety of loncastuximab tesirine in relapsed or refractory diffuse large B-cell ly…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: ImmunoMRI for Assessment of Tumor-associated Macrophages [EARLY_Phase 1]
A Phase 1 clinical trial update evaluating ImmunoMRI as a biomarker to assess tumor-associated macrophages in diffuse large B-cell lymphoma.
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: A Multicenter Observational Study to Understand the Clinical Characteristics, Treatment Patterns and Access to Novel Therapies of Patients With Diffuse Large B-Cell Lymphoma in the MEA Region
An observational multicenter study sponsored by AstraZeneca to understand the clinical characteristics, treatment patterns, and access to no…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Glofitamab Bridging ASCT for Patients With Relapsed or Refractory DLBCL [Phase 2]
Phase 2 trial evaluating glofitamab as a bridging therapy to autologous stem cell transplantation for patients with relapsed or refractory d…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Predictive Value of CRP, Albumin, CAR, and mGPS in Treatment Outcomes of DLBCL
Prospective clinical trial at Ain Shams University investigating whether inflammatory biomarkers (CRP, albumin, CAR, and mGPS) predict treat…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Tumor Associated Antigen Specific T Cells (TAA-T) With PD1 Inhibitor for Lymphoma [Phase 1]
Phase 1 clinical trial investigating tumor-associated antigen-specific T cells (TAA-T) in combination with a PD-1 inhibitor for Hodgkin lymp…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A First-in-human Study to Assess OT-C001 (Amplified/Activated Allogenic Natural Killer Cells) in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma [Phase 1]
This is a first-in-human Phase 1 trial evaluating OT-C001, amplified/activated allogeneic natural killer cells, in patients with relapsed/re…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders [Phase 2]
Phase 2 clinical trial evaluating myeloablative allogeneic hematopoietic stem cell transplantation from related or unrelated donors for a br…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: A Phase II Trial of 4 vs 6 Cycles of CHP Combined With Polatuzumab Vedotin-Rituximab in Untreated DLBCL Patients With IPI 0-1 [Phase 2]
A Phase II clinical trial evaluating 4 versus 6 cycles of CHP in combination with Polatuzumab vedotin and Rituximab for previously untreated…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Evaluation of the Efficacy and Safety of Polatuzumab Vedotin Combined With Rituximab, Gemcitabine, and Oxaliplatin (Pola-R-GemOx) as Salvage Therapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) Patients Ineligible for Autologous Transplantation [Phase 2]
Phase 2 clinical trial evaluating Polatuzumab Vedotin in combination with Rituximab, Gemcitabine, and Oxaliplatin (Pola-R-GemOx) as salvage …
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Bispecific Antibody-Based Salvage Therapy Followed by CAR-T ± ASCT in R/R Aggressive B-Cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating a bispecific antibody-based salvage therapy followed by CAR-T cell therapy, with or without autologous ste…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Clinical Study of C402-CD19-CAR Treatment in Subjects With Relapsed or Refractory B-cell Lymphoma [Phase 1]
Phase 1 clinical trial evaluating C402-CD19-CAR for relapsed or refractory B-cell lymphomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: The Role of Surgical Resection AND Stereotactic Radiosurgery in Primary Central Nervous System -Diffuse Large B Cell Lymphoma
This completed clinical trial investigates the potential role of surgical resection and stereotactic radiosurgery in treating primary centra…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Pembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma [Phase 2]
This clinical trial update describes a Phase 2 study at the University of Chicago assessing pembrolizumab plus chemotherapy for untreated B-…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies
A clinical trial is investigating the effectiveness and safety of the CAR-T therapy tisagenlecleucel in Brazilian patients with B-lymphocyte…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Vaccination Against Human Papillomavirus (HPV) After Allogeneic Stem Cell Transplantation [Phase 2]
This Phase 2 trial investigates HPV vaccination in recipients of allogeneic stem cell transplantation and is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas [Phase 1, Phase 2]
Clinical trial update for Tulmimetostat DZR123 (CPI-0209) in adults with advanced solid tumors and various lymphomas. The study is in Phase …
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: GVM±R in Patients With Relapsed or Refractory Aggressive NHL. [Phase 2]
Phase 2 clinical trial update for GVM±R in adults with relapsed or refractory aggressive non-Hodgkin lymphoma, including Peripheral T-cell l…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: R-CMOP in Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the Rituximab-based R-CMOP regimen in newly diagnosed diffuse large B-cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Phase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell Lymphoma [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of PL001, a CD19 CAR-T cell therapy, for relapsed or refractory B-cell lymphoma. The …
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Long-term Follow-up Study of Lentiviral-based Gene-edited Immune Cell Therapy
This clinical trial registry entry describes a long-term follow-up study of a lentiviral-based gene-edited immune cell therapy for several B…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy [NA]
Clinical trial update on evaluating comprehensive geriatric assessment to predict toxic events in older patients with Non-Hodgkin lymphoma, …
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Zanubrutinib, Lenalidomide and Rituximab (ZR2) in Elderly Treatment-naive Patients With Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 trial update for Zanubrutinib, Lenalidomide and Rituximab (ZR2) in elderly, treatment-naive Diffuse large B-cell lymphoma. The study…