Diarrhea
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Sign up freeTop drugs studied for this disease
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FDA label_change · 2018-12-11FDA Approved: IMODIUM MULTI-SYMPTOM RELIEF — Supplemental Application (Kenvue Brands LLC)
The FDA approved a supplemental application for Imodium Multi-Symptom Relief (loperamide hydrochloride and dimethicone) submitted by Kenvue …
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Efficacy of Rifaximin in Preventing Campylobacteriosis [Phase 2, Phase 3]
Clinical trial update on rifaximin for prevention of Campylobacteriosis shows completed Phase 2/3 study results; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-13Clinical Trial Update: Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate [Phase 1, Phase 2]
Clinical trials for WRSS1, a Shigella sonnei vaccine candidate, completed Phase 1/2 to assess safety and efficacy for dysentery caused by Sh…
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FDA approval · 2018-11-13FDA Approved: DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE — Original Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved an original application for a generic product of diphenoxylate hydrochloride and atropine sulfate (anti-diarrheal) by Unichem P…
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CLINICAL_TRIALS trial_result · 2018-11-07Clinical Trial Update: Spinal Cord Stimulation for Pain Relief in Irritable Bowel Syndrome [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating spinal cord stimulation for pain relief in irritable bowel syndrome. The study includes IBS …
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FDA approval · 2018-09-05FDA Approved: ANTI DIARRHEAL ANTI GAS — Original Application (Rite Aid Corporation)
FDA approved a generic anti-diarrheal and anti-gas product containing loperamide hydrochloride and simethicone via an Original Application (…
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: Oral Zinc for the Treatment of Acute Diarrhea in US Children [NA]
Clinical trial update on oral zinc for treating acute diarrhea in US children; study completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: CASAD for Severe Diarrhea in the Emergency Department [NA]
This terminated clinical trial evaluated CASAD for severe diarrhea in cancer patients, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults [Phase 2]
The document reports the completion of a Phase 2 trial evaluating multiple formulations of a Clostridioides difficile toxoid vaccine given o…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children [NA]
This clinical trial update describes the impact of preventive and therapeutic zinc supplementation programs among young children. The study …
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: WASH Benefits Kenya [NA]
A completed trial in Kenya assessing WASH Benefits interventions related to malnutrition and diarrhea, with measured child development outco…
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes [NA]
The document reports completion of a clinical trial evaluating the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) and its effect …
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Probiotics for the Prevention of Antibiotic-Associated Diarrhea [NA]
A clinical trial evaluating probiotics to prevent antibiotic-associated diarrhea was terminated.
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Oral Disintegrating Ondansetron Tablet to Reduce Vomiting From Gastroenteritis in a Pediatric Emergency Department [NA]
A pediatric trial evaluating an oral disintegrating ondansetron tablet to reduce vomiting from gastroenteritis in the emergency department h…
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CLINICAL_TRIALS research · 2018-03-20Clinical Trial Update: Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial [Phase 4]
This document outlines the protocol for a Phase 4 randomized controlled trial to evaluate whether Lactobacillus reuteri DSM 17938 can preven…
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CLINICAL_TRIALS trial_result · 2018-03-02Clinical Trial Update: Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in EDs in Pakistan [Phase 4]
A Phase 4 trial evaluating ondansetron in children with gastroenteritis, vomiting and dehydration in emergency departments in Pakistan has c…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in Children [Phase 4]
Phase 4 clinical trial assessing the effects of probiotics and/or prebiotics on duration of diarrhea and hospitalization in children with ac…
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Study of the Efficacy and Tolerance of Oral Treatment With a Total Freeze-dried Culture of Lcr Restituo® Sachets (Lactobacillus Rhamnosus Lcr35®) on Intolerance to Metformin (Diarrhoea) in Patients With Diabetes Type 2 [Phase 2]
Phase 2 trial assessing oral Lcr Restituo (Lactobacillus rhamnosus Lcr35) for metformin-induced diarrhea in type 2 diabetes patients; status…
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CLINICAL_TRIALS trial_result · 2017-12-19Clinical Trial Update: Solar Water Disinfection Intervention Trial in Bolivia [Phase 3]
Phase 3 clinical trial update on a solar water disinfection intervention for diarrhea; study completed.
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi [NA]
This completed trial evaluated whether sending text message reminders to health workers improves case management for malaria, pneumonia, and…
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea [Phase 4]
A Phase 4 clinical trial evaluating oral tannins and flavonoids for acute diarrhea in children has completed.
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Oral Rehydration SolutionContaining Amylase Resistant Starch in Severely Malnourished Children. [Phase 3]
Phase 3 trial evaluating an oral rehydration solution containing amylase resistant starch in severely malnourished children with diarrhea ha…
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: A Study on Immunological Effect of Vitamin A and Zinc in a Placebo Controlled 4 Cell Trial [NA]
Completed placebo-controlled trial assessing the immunological effects of Vitamin A and zinc. The study addressed diarrhea and respiratory t…
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Hospital Onset Diarrhoea Investigation
A clinical trial investigating hospital onset diarrhea sponsored by The Leeds Teaching Hospitals NHS Trust has completed.
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FDA approval · 2017-10-05FDA Approved: LOMOTIL — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
The FDA approved a supplemental application for Lomotil (diphenoxylate hydrochloride and atropine sulfate) from Pfizer Laboratories Div Pfiz…