Diarrhea
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: Prevention of Traveler's Diarrhea [Phase 2]
A Phase 2 clinical trial evaluating prevention of traveler's diarrhea has completed.
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM) [Phase 2]
Phase 2 trial of aldafermin (NGM282) for chronic diarrhea due to bile acid malabsorption has completed with results posted.
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FDA approval · 2023-09-05FDA Approved: LOPERAMIDE HYDROCHLORIDE — Original Application (Aurobindo Pharma Limited)
The FDA approved Aurobindo Pharma Limited's Original Application for Loperamide hydrochloride, granting approval of a generic anti-diarrheal…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Octreotide Compared With Loperamide Hydrochloride for Chemotherapy-Related Diarrhea in Patients With Colorectal Cancer [Phase 3]
Phase 3 trial comparing octreotide to loperamide for chemotherapy-related diarrhea in colorectal cancer patients has completed.
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery [Phase 4]
A phase 4 trial comparing ciprofloxacin to azithromycin for children hospitalized with dysentery due to Shigella has completed.
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: Prospective Randomized Open Label Study of the Treatment of Therapy-associated Diarrhea During Percutaneous Radiation Therapy of the Small Pelvis. - Comparison of Loperamide and Tincture of Opium - [Phase 3]
A randomized phase 3 trial evaluating loperamide versus tincture of opium for therapy-associated diarrhea during pelvic radiotherapy has bee…
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CLINICAL_TRIALS withdrawal · 2023-05-06Clinical Trial Update: Investigation of Eluxadoline for Diabetic Diarrhea [Phase 2, Phase 3]
Clinical trial investigating eluxadoline for diabetic diarrhea was withdrawn.
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CLINICAL_TRIALS trial_result · 2023-04-19Clinical Trial Update: Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With Vascular Endothelial Growth Factor-Tyrosine Kinase Inhibitor [NA]
Clinical trial evaluating a probiotic yogurt supplement to reduce diarrhea in patients with metastatic renal cell carcinoma treated with VEG…
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FDA approval · 2023-03-23FDA Approved: LOPERAMIDE HYDROCHLORIDE — Original Application (Zydus Lifesciences Limited)
FDA approved the original application for loperamide hydrochloride from Zydus Lifesciences Limited. The approval enables a generic version o…
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CLINICAL_TRIALS research · 2023-03-01Clinical Trial Update: Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol) [Phase 4]
Phase 4 trial investigating oral bismuth subsalicylate (Pepto-Bismol) for diarrhea in COVID-19 patients; study completed with results posted…
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CLINICAL_TRIALS trial_result · 2023-02-22Clinical Trial Update: GastroIntestinal Panel in Kidney Transplant Patients [Phase 3]
Phase 3 clinical trial update on a GastroIntestinal Panel in kidney transplant patients, with conditions including kidney transplant complic…
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FDA approval · 2023-01-26FDA Approved: LOPERAMIDE HYDROCHLORIDE — Original Application (Advagen Pharma Ltd.,)
FDA approved Advagen Pharma Ltd.'s original application for loperamide hydrochloride (a generic anti-diarrheal) to treat various forms of di…
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CLINICAL_TRIALS trial_result · 2023-01-11Clinical Trial Update: The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children [Phase 4]
Phase 4 clinical trial assessing the effectiveness of Pleuran for treating acute gastroenteritis in children has been completed.
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Prevention of Irinotecan Induced Diarrhea by Probiotics [Phase 3]
Phase 3 trial update on using probiotics to prevent irinotecan-induced diarrhea in cancer patients has completed.
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FDA approval · 2022-11-22FDA Approved: LOPERAMIDE HCL AND SIMETHICONE — Supplemental Application (Ohm Laboratories Inc.)
The FDA approved a supplemental application for Loperamide HCl and Simethicone from Ohm Laboratories Inc., updating labeling for the combina…
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: Response to Rotavirus Vaccine in Infants in Ho Chi Minh City in Vietnam [Phase 4]
Phase 4 clinical trial update evaluating response to rotavirus vaccine in infants in Ho Chi Minh City, Vietnam.
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs [Phase 2]
Phase 2 clinical trial update evaluating an amino acid–based medical food for diarrhea in neuroendocrine tumors, including carcinoid syndrom…
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FDA approval · 2022-08-29FDA Approved: LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE — Original Application (Granules India Ltd)
FDA approved Granules India Ltd's original application for a generic combination product containing loperamide hydrochloride and simethicone…
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CLINICAL_TRIALS trial_result · 2022-08-23Clinical Trial Update: Effect of the Sequestrant Colesevelam in Bile Acid Diarrhoea [Phase 4]
A Phase 4 clinical trial evaluating the effectiveness of the sequestrant colesevelam for bile acid diarrhea due to bile acid malabsorption a…
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CLINICAL_TRIALS trial_result · 2022-05-19Clinical Trial Update: Effectiveness of Folic Acid Supplementation in Acute Watery Diarrhea Among Children Under 5 Years of Age [Phase 4]
Phase 4 trial evaluating the effectiveness of folic acid supplementation in acute watery diarrhea among children under 5.
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CLINICAL_TRIALS trial_result · 2022-05-19Clinical Trial Update: Prevention of Clostridium Difficile-associated Diarrhea by Daily Intake of Kefir [Phase 2]
Phase 2 trial assessing daily kefir intake to prevent Clostridium difficile-associated diarrhea; study terminated with results posted in 202…
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FDA approval · 2021-12-13FDA Approved: ANTI DIARRHEAL — Supplemental Application (H E B)
FDA approved a supplemental application for a generic anti-diarrheal drug containing loperamide hydrochloride (LOPERAMIDE HCL).
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CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: The Efficacy of Asacol (Mesalazine) Suppository on the Treatment of Diarrhea-Induced Acute Fissure [Phase 1, Phase 2]
Phase 1/2 trial evaluating Asacol (mesalazine) suppository for diarrhea-induced acute fissure; study completed.
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FDA approval · 2021-10-06FDA Approved: LOPERAMIDE HYDROCHLORIDE — Original Application (Edenbridge Pharmaceuticals LLC.)
FDA approved Edenbridge Pharmaceuticals' original application for a generic version of loperamide hydrochloride.
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FDA approval · 2021-09-10FDA Approved: ANTI-DIARRHEAL/ANTI-GAS CAPLETS — Original Application (YYBA CORP)
FDA approved YYBA CORP's original application for a combination anti-diarrheal and anti-gas caplet containing loperamide hydrochloride 2 mg …