Diabetic Nephropathy
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: MMP-9/NGAL Modulation by Piper Crocatum in Early Diabetic Nephropathy [NA]
Completed clinical trial investigating modulation of MMP-9/NGAL by Piper crocatum extract in early diabetic nephropathy.
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: Effect of High Intensity Interval Versus Moderate Intensity Continuous Training on Microalbuminurea [NA]
A completed clinical trial comparing high-intensity interval training to moderate-intensity continuous training and its effect on microalbum…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: The Effect of Combined Dulaglutide and Dapagliflozin Treatment vs DPP-4 Inhibitors in Endothelial and Vascular Function in Patients With Type 2 Diabetes Mellitus and Albuminuria [NA]
This clinical trial update describes a study comparing the combination of dulaglutide and dapagliflozin to DPP-4 inhibitors in adults with t…
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CLINICAL_TRIALS trial_result · 2024-09-20Clinical Trial Update: This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated [Phase 1]
A phase 1 international study assesses three doses of BI 690517 in patients with diabetic nephropathy to evaluate how the drug is absorbed a…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Combined Diabetes-Renal Multifactorial Intervention In Patients With Advanced Diabetic Nephropathy (ADN) [NA]
Clinical trial update for a combined diabetes-renal multifactorial intervention in patients with advanced diabetic nephropathy; the study st…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: A Study to Test the Effect of Different Doses of BI 685509 on Kidney Function in People With Diabetic Kidney Disease [Phase 2]
A Phase 2 trial evaluating different doses of BI 685509 for kidney function in diabetic kidney disease has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-07-15Clinical Trial Update: Efficacy and Safety of Canagliflozin (TA-7284) in Patients With Diabetic Nephropathy [Phase 3]
Phase 3 trial evaluating the efficacy and safety of canagliflozin (TA-7284) in patients with diabetic nephropathy has completed with results…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Impact of Silymarin Adjunct Therapy on Proteinuria in Type 2 Diabetic Patients on RAS Inhibitors [Phase 2]
Phase 2 trial evaluating silymarin as an adjunct therapy on proteinuria in type 2 diabetes patients on renin-angiotensin system inhibitors h…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Macrovascular and Microvascular Morbidity and Mortality After Metabolic Surgery Versus Medicines
This completed clinical trial compares long-term macrovascular and microvascular morbidity and mortality after metabolic (bariatric) surgery…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Investigational and Comparative Study in the Management of Diabetic Nephropathy [Phase 3]
A Phase 3 trial evaluating an investigational and comparative treatment for diabetic nephropathy in type 2 diabetes has completed enrollment…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Dosimetry of Tc-99m-Tilmanocept [Phase 1]
A Phase 1 trial to assess the dosimetry of Tc-99m-Tilmanocept in diabetic nephropathy, with recruitment ongoing.
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: Impact of Dapagliflozin as Add-on Therapy on Glycemic Status and Quality of Life in Type 2 Diabetic Patients [Phase 4]
Phase 4 trial update evaluating dapagliflozin as add-on therapy for glycemic status and quality of life in type 2 diabetes with diabetic nep…
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study) [Phase 4]
A Phase 4 randomized trial comparing telmisartan to losartan in hypertensive patients with type 2 diabetes and overt nephropathy; completed.
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Study of the Protective Effect of Low-dose Aspirin on Renal Function in Patients With Early Diabetic Nephropathy [Phase 2, Phase 3]
Phase 2/3 trial investigating whether low-dose aspirin protects renal function in patients with early diabetic nephropathy.
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Effect of Pirfenidone on Glomerular Filtration Rate and Albuminuria in Patients With Diabetic Nephropathy [Phase 3]
A Phase 3 clinical trial assessing pirfenidone effects on glomerular filtration rate and albuminuria in patients with diabetic nephropathy h…
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Safety and Efficacy of Two Year of RAAS Alone or in Combination With Spironolactone Therapy [Phase 4]
A Phase 4 trial update assessing safety and efficacy of RAAS therapy alone or with spironolactone in chronic renal insufficiency and diabeti…
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CLINICAL_TRIALS trial_result · 2022-10-20Clinical Trial Update: Niclosamide Role in Diabetic Nephropathy [Phase 3]
Phase 3 clinical trial investigating niclosamide for diabetic nephropathy has completed.
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CLINICAL_TRIALS trial_result · 2022-08-31Clinical Trial Update: Vitamin D Supplementation in Diabetic Nephropathy [Phase 2]
Phase 2 trial update on vitamin D supplementation in patients with diabetic nephropathy and sub-optimal vitamin D status, completed.
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Safety, Tolerability and Efficacy of Nidufexor in Patients With Diabetic Nephropathy [Phase 2]
Phase 2 clinical trial update on Nidufexor in diabetic nephropathy reports safety, tolerability, and efficacy outcomes.
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CLINICAL_TRIALS trial_result · 2022-05-13Clinical Trial Update: Comparison Between the Efficacy of SGLT2 Inhibitor Therapy Versus ACE Inhibitor in the Treatment of Diabetic Kidney Disease [Phase 2, Phase 3]
A clinical trial comparing SGLT2 inhibitor therapy to an ACE inhibitor for diabetic nephropathy (Phase 2/3) with unknown current status.
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CLINICAL_TRIALS trial_result · 2021-12-07Clinical Trial Update: The Effects of TMZ on Diabetic Nephropathy [Phase 2]
Phase 2 trial updating the effects of temozolomide (TMZ) on diabetic nephropathy is ongoing with unknown status.
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CLINICAL_TRIALS trial_result · 2021-08-31Clinical Trial Update: Evaluation of Coffee Therapy for Improvement of Renal Oxygenation [Phase 2]
Phase 2 clinical trial evaluating coffee therapy to improve renal oxygenation; completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathy [Phase 2]
A Phase 2 clinical trial evaluating safety, tolerability, and renal effects of APX-115 in subjects with type 2 diabetes and nephropathy has …
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CLINICAL_TRIALS trial_result · 2021-08-23Clinical Trial Update: European Trial of Immunosuppression in SPK Tx [Phase 3]
Phase 3 trial update of immunosuppression in simultaneous kidney-pancreas transplantation has completed.
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients [Phase 2]
Phase 2 study evaluating safety and efficacy of CTP-499 in patients with type 2 diabetic nephropathy (type 2 diabetes mellitus with chronic …