Diabetic Macular Edema
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: Effectiveness Of Suprachoroidal Injection In Diabetic Macular Edema
This update discusses a clinical trial evaluating the effectiveness of suprachoroidal injections for diabetic macular edema. The trial is cu…
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema [Phase 4]
A Phase 4 study comparing dexamethasone intravitreal implant to intravitreal aflibercept in diabetic macular edema has completed.
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: iOCT for Patients With Diabetic Macular Edema [NA]
A completed clinical trial update evaluating the use of intraoperative optical coherence tomography (iOCT) in patients with diabetic macular…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Vitrectomy and Bevacizumab for Diffuse Diabetic Macular Edema [Phase 3]
A Phase 3 trial evaluating the combination of vitrectomy and bevacizumab for diffuse diabetic macular edema has been terminated.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Changes in Inflammatory Biomarkers Including Soluble CD14 and Hyperreflective Foci in DME Patients Treated With Aflibercept (FORESIGHT) [Phase 4]
This Phase 4 FORESIGHT trial update reports changes in inflammatory biomarkers, including soluble CD14 and hyperreflective foci, in patients…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD) [Phase 2]
Phase 2 BEHOLD study assessing safety, tolerability, and preliminary activity of UBX1325 in diabetic macular edema; results have been posted…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: The Study of CU06-1004 in Patients With Diabetic Macular Edema (DME) [Phase 2]
Phase 2 clinical trial update showing completion of the study evaluating CU06-1004 in Diabetic Macular Edema.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: DRCR.Net Aflibercept vs. Bevacizumab + Deferred Aflibercept for the Treatment of CI-DME [Phase 3]
A DRCR.Net Phase 3 trial comparing aflibercept monotherapy to bevacizumab with deferred aflibercept for central-involved diabetic macular ed…
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: Clinical Study of the Safety and Efficacy of BAT5906 Injection [Phase 1, Phase 2]
Clinical study evaluating safety and efficacy of BAT5906 Injection in diabetic macular edema completed (Phase 1 and Phase 2).
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: One Year Trial Evaluating Safety of Ozurdex With Eylea [Phase 4]
A Phase 4 trial evaluating the safety of Ozurdex with Eylea in diabetic macular edema has completed.
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema [Phase 1, Phase 2]
Clinical trial update reports safety and bioactivity data for AXT107 in diabetic macular edema, with the study terminated.
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Compare the Efficacy of VItrectomy Combined With DExamethasone Implant Versus With Aflibercept in DME Patients Diagnosed by Intraoperative OCT (the VIDEO Study): Study Protocol for a Randomized Controlled Trial [Phase 4]
A study protocol for a Phase 4 randomized controlled trial comparing vitrectomy with dexamethasone implant versus aflibercept in diabetic ma…
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Bangladesh PRODUCTIVity in Eyecare Trial [NA]
Clinical trial update for the Bangladesh PRODUCTIVity in Eyecare trial; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: A Study of the Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema [Phase 3]
A Phase 3 study comparing the efficacy and safety of brolucizumab versus aflibercept in diabetic macular edema has completed with results po…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Evaluation of RC28-E Injection in Diabetic Macular Edema [Phase 2]
Phase 2 clinical trial update evaluating RC28-E injection for diabetic macular edema has been completed.
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CLINICAL_TRIALS trial_result · 2023-12-05Clinical Trial Update: Study to Compare Efficacy and Safety of CT-P42 in Comparison With Eylea in Patients With Diabetic Macular Edema [Phase 3]
A Phase 3 trial comparing CT-P42 with Eylea in diabetic macular edema has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-01Clinical Trial Update: A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab [Phase 2]
Phase 2 trial investigating faricimab in treatment-naïve diabetic macular edema with multimodal imaging biomarkers; study completed and resu…
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CLINICAL_TRIALS trial_result · 2023-11-27Clinical Trial Update: A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema [Phase 2]
Phase 2 trial evaluating THR-149 for diabetic macular edema has completed.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease [Phase 2, Phase 3]
A Regeneron trial evaluated high-dose aflibercept for diabetic macular edema in diabetic eye disease. The Phase 2/3 study has completed, and…
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular Edema [Phase 2]
Phase 2 study evaluating multiple-dose safety and efficacy of LKA651 in diabetic macular edema; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: A Study in Patients With Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema to Evaluate the Safety of the Faricimab Prefilled Syringe [Phase 3]
Phase 3 trial update assessing the safety of the faricimab prefilled syringe in patients with neovascular age-related macular degeneration o…
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CLINICAL_TRIALS trial_result · 2023-09-05Clinical Trial Update: Efficacy and Safety of RC28-E Versus Aflibercept in Diabetic Macular Edema [Phase 3]
A Phase 3 clinical trial comparing RC28-E to aflibercept for efficacy and safety in diabetic macular edema is currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-08-18Clinical Trial Update: A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema. [Phase 2]
Phase 2 trial update for THR-687 in diabetic macular edema was terminated; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: Safety and Exploratory Efficacy Study of SF0166 for the Treatment of Diabetic Macular Edema (DME) [Phase 1, Phase 2]
Clinical trial update for SF0166 in diabetic macular edema reports completed Phase 1/2 with safety and exploratory efficacy data.
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Efficacy and Safety Study of Intravitreal Triamcinolone to Treat Diffuse Diabetic Macular Edema [Phase 3]
Phase 3 trial evaluating intravitreal triamcinolone for diffuse diabetic macular edema has completed.