Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Generative Artificial Intelligence Intervention and Individual Psychological Counseling on Emotional Distress in Young Adults [NA]
A clinical trial is evaluating the impact of a generative AI intervention combined with individual psychological counseling on emotional dis…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Study on the Mechanism of Multi-group Analysis of the Influence of Depression on Common Cardiovascular Diseases
A clinical trial protocol investigating the mechanism by which depression may influence common cardiovascular diseases using multi-group ana…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa [Phase 3]
Phase 3 trial in South Africa evaluating a resilience-oriented family intervention to prevent adolescent HIV/STI infection and depression ha…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Randomized Clinical Trial of a Multi-Modal Palliative Care Intervention [NA]
A randomized trial evaluating a multi-modal palliative care intervention for patients with metastatic cancer who have depression and anxiety…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Effect of WBT for CI With Depression [NA]
A clinical trial entry notes the study of web-based behavioral therapy for chronic insomnia with depressive disorders and indicates recruitm…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients [Phase 1, Phase 2]
This clinical trial update describes Phase 1/2 studies of Roxadustat in hemodialysis patients, focusing on bone health and neuropsychiatric …
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Northern Manhattan Study of Metabolism and Mind
This clinical trial update describes the Northern Manhattan Study of Metabolism and Mind (NCT02470260), sponsored by Columbia University, in…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: An Epidemiology Study of Treatment Resistant Depression in the United States (US)
This is a completed epidemiology study in the United States examining treatment-resistant depression, sponsored by Janssen Research & Develo…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Cooperation for Primary Care Patients on Sick Leave for CMD: Care Manager and Workplace Intervention - CO-WORK-CARE [NA]
Göteborg University reports the CO-WORK-CARE trial investigating a care manager and workplace intervention for primary care patients on sick…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Functional Connectivity Alterations in Suicidal Patients Among Opioid Users [NA]
A Baylor College of Medicine study is recruiting to examine functional connectivity alterations in suicidal patients with opioid use, explor…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: The Relationship Between Fibromyalgia Syndrome Parameters With Disease-Pain Severity and the Quality Of Life
A completed clinical trial investigates how fibromyalgia parameters relate to disease-pain severity and quality of life, noting comorbid anx…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: OSU6162 as add-on in SSRI/SNRI-resistant Depression [Phase 2]
A Phase 2 clinical trial evaluating OSU6162 as an add-on therapy for SSRI/SNRI-resistant depression; it is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Psilocybin in Alcohol Use Disorder With Comorbid Depression [NA]
A completed clinical trial assessing psilocybin for alcohol use disorder with comorbid depression (sponsored by Centre Hospitalier Universit…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Module-Based Psychological (MBP) for Community Youths [NA]
A clinical trial update from The University of Hong Kong on Module-Based Psychological (MBP) for community youths; the study is listed as ac…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: A Mental Health Services Engagement Program for Racial and Ethnic Minority Young Adults [NA]
New York University is recruiting for a mental health services engagement program for racial and ethnic minority young adults with psychosis…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa [NA]
Results from a completed clinical trial in South Africa evaluated community health worker training to reduce depression and substance use st…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Boricua Youth Study COVID-19 Coping Intervention Study [NA]
The Boricua Youth Study COVID-19 Coping Intervention Study is currently suspended.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: The Effect of Gliatamin (Chonline Alphoscerate) on Depressive Mood in Type 2 Diabetes Patients [Phase 4]
This document reports a Phase 4 clinical trial evaluating Gliatamin (Choline alfoscerate) for depressive mood in adults with Type 2 diabetes…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Co-occurence of Mental Illness and Problematic Alcohol Use: an Internet-based Cognitive Behavior Therapy Intervention [NA]
A clinical trial evaluating an internet-based cognitive behavioral therapy intervention for individuals with co-occurring mental illness and…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: 7T Amygdala and Citalopram Study [NA]
This entry notes an ongoing University of Oxford study using 7T amygdala imaging to investigate the effects of citalopram on emotional proce…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Urban and Insular Study on Treatment Experiences and Stigma in People Living with HIV
A clinical study assessing treatment experiences and stigma among people living with HIV, with attention to related mental health issues suc…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Telephone-administered Relapse Prevention for Depression [NA]
A completed clinical trial evaluating telephone-administered relapse prevention for depression conducted by the University of Zurich.
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Effects of TDCS Intervention on Neoadjuvant Chemotherapy in Breast Cancer Patients with Mild to Moderate Depression [NA]
A clinical trial is evaluating transcranial direct current stimulation (TDCS) as an adjunct to neoadjuvant chemotherapy in breast cancer pat…
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CLINICAL_TRIALS withdrawal · 2025-02-04Clinical Trial Update: Mood Disorders in Head and Neck Cancer Patients [Phase 4]
Phase 4 clinical trial investigating mood disorders in head and neck cancer patients has been withdrawn.
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Efficacy of taVNS Versus Sham Stimulation in Reduing Depressive Symptoms in Patients With Epilepsy: a Multi-center, Double-blinded, Randomized, 20-week, Parallel-arm, Superiority Study [NA]
A multi-center, double-blind trial compares taVNS to sham to evaluate reduction of depressive symptoms in patients with epilepsy over 20 wee…