Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2009-07-16Clinical Trial Update: Study In Patients With Depression Not Responding to Selective Serotonin Re-uptake Inhibitors [Phase 3]
Phase 3 trial update for patients with depression not responding to SSRIs; results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-03-12Clinical Trial Update: An Eight-Week Study to Evaluate the Efficacy and Safety of SR58611A in Elderly Patients With Depression [Phase 3]
A Phase 3 trial completed evaluating the efficacy and safety of SR58611A in elderly patients with depressive disorder.
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CLINICAL_TRIALS research · 2009-02-13Clinical Trial Update: Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study [Phase 4]
Phase 4 clinical trial update examining the effect of paroxetine on tramadol metabolism and pharmacodynamics in a dose-response study for de…
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CLINICAL_TRIALS trial_result · 2008-10-01Clinical Trial Update: The Effect of Testosterone on Mood and Quality of Life [NA]
A completed clinical trial assessed the effect of testosterone on mood and quality of life in individuals with gonadal disorders, depressive…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial [Phase 2]
A Phase 2 double-blind, placebo-controlled trial evaluating omega-3 fatty acids for treating bipolar disorder has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Acute Effectiveness of Additional Drugs to the Standard Treatment of Depression [Phase 2]
Phase 2 trial evaluating the acute effectiveness of additional drugs added to standard treatment for depression; the study has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
A completed clinical trial evaluated mood-related adverse effects associated with progestin use, including depressed mood, irritability, and…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Consequences of Conjugal Bereavement in Adults
This completed clinical trial, led by the National Institute of Mental Health, examined the mental health consequences of conjugal bereaveme…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Glucocorticoid Effects on Cellular Cytokine Release
A completed clinical trial from NIMH examined the effects of glucocorticoids on cellular cytokine release across conditions such as depressi…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Psychosocial Correlates and Coping Strategies Associated With Long-Term Survival of HIV-Infected Children
This clinical trial update examines psychosocial factors and coping strategies linked to long-term survival in HIV-infected children, based …
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CLINICAL_TRIALS trial_result · 2007-10-30Clinical Trial Update: Efficacy Study of a Computer Decision Support System to Treat Depression [NA]
The completed clinical trial evaluated the efficacy of a computer decision support system for treating depressive disorder.
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FDA label_change · 2007-08-02FDA Approved: WELLBUTRIN XL — Supplemental Application (Bausch Health US LLC)
FDA approved a supplemental application for WELLBUTRIN XL, resulting in changes to the product labeling.
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CLINICAL_TRIALS trial_result · 2007-04-19Clinical Trial Update: Nicotinic Receptor Augmentation of SSRI Antidepressants [Phase 2]
Phase 2 clinical trial evaluating augmentation of SSRI antidepressants with nicotinic receptor modulation in depressive disorder; the study …
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CLINICAL_TRIALS research · 2007-04-19Clinical Trial Update: PET Neuroimaging of [11C]Mirtazapine [Phase 4]
Phase 4 PET imaging study using radiolabeled [11C]mirtazapine to investigate brain binding in mood and depressive disorders; the trial statu…