Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Functional MRI Before and After Treatment for Depression [NA]
A terminated Stanford-sponsored clinical trial evaluated functional MRI before and after treatment for depression, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Desvenlafaxine vs. Placebo Treatment of Chronic Depression [Phase 4]
Phase 4 trial comparing desvenlafaxine to placebo in chronic depression shows completed study with posted results.
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: Effects of Psychoeducation of Relatives to Patients With Serious Mental Illness [NA]
A completed clinical trial studied the effects of psychoeducation for relatives of patients with serious mental illness, including schizophr…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE) [Phase 4]
A Phase 4 clinical trial evaluating CYP2D6 metabolic screening in elderly patients taking antidepressants for depression has completed, inve…
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: A Study To Evaluate The Effect Of WELLBUTRIN XL On Intraocular Pressure [Phase 1]
Phase 1 study assessing whether WELLBUTRIN XL (bupropion extended-release) affects intraocular pressure in individuals with depressive disor…
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: 28-day Repeat Dose and Drug Interaction Study With Orvepitant (GW823296) [Phase 1]
A Phase 1 clinical trial update reports results from a 28-day repeat-dose and drug interaction study of Orvepitant (GW823296) in depressive …
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: PAXIL CR Bioequivalence Study [Phase 1]
GlaxoSmithKline completed a Phase 1 bioequivalence study of Paxil CR (paroxetine controlled-release) for Depressive Disorder.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Food and Relative Bioavailability Study [Phase 1]
Phase 1 study update on food effect and relative bioavailability sponsored by GlaxoSmithKline for a depressive disorder indication.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: A Study To Investigate Effects Of GSK561679 On Brain Activation During Emotional Processing In Healthy Volunteers [Phase 1]
This Phase 1 study investigated the effects of GSK561679 on brain activation during emotional processing in healthy volunteers. The trial st…
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CLINICAL_TRIALS trial_result · 2017-07-07Clinical Trial Update: Emotional Processing in Healthy Volunteers in the Presence of an Investigational Anxiolytic [Phase 1]
A Phase 1 study by GlaxoSmithKline evaluating emotional processing in healthy volunteers in the presence of an investigational anxiolytic; t…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain DAT and SERT Occupancy,Pharmacokinetics and Safety of Single Oral Doses of GSK1360707, Using 11C- PE2I and 11C-DASB as PET Ligands [Phase 1]
Phase 1 open-label PET study in healthy male subjects to evaluate brain DAT and SERT occupancy, pharmacokinetics, and safety after single or…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: The Impact of Giving a Massage [EARLY_Phase 1]
This early Phase 1 trial evaluated the impact of giving a massage on mental-state measures related to depression, anxiety, or stress; the st…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Bupropion and Specific Cardiovascular Malformations
A completed clinical trial update on bupropion exposure during pregnancy and its possible link to congenital cardiovascular malformations.
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission [NA]
This clinical trial update reports the completion of a study evaluating a training protocol to cope with negative repetitive thinking in peo…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks
A completed clinical trial evaluated a health plan–level initiative to mitigate risks from chronic opioid therapy, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Pharmacological Intervention in Depression After Traumatic Brain Injury [Phase 4]
A Phase 4 clinical trial evaluating a pharmacological intervention for depression following traumatic brain injury has completed.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Spot Depression Study
The update notes the completion of the Spot Depression Study (NCT02804867) conducted by the University of Cambridge, investigating treatment…
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: PET (Positron Emission Tomography)/Public Speaking Study With A Combination Of 2 Medications In Social Anxiety Patients [Phase 2]
Phase 2 PET/public speaking trial using a two-drug combination in social anxiety disorder has completed; results are not detailed in the pro…
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Developing and Testing of Culturally Adapted Cognitive Behavior Therapy (CaCBT) for Pashto Speaking Pakistanis and Afghans [NA]
A completed clinical trial evaluating culturally adapted cognitive-behavioral therapy for Pashto-speaking Pakistanis and Afghans with depres…
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Research Evaluating the Value of Augmenting Medication With Psychotherapy [Phase 4]
Phase 4 trial evaluating whether augmenting medication with psychotherapy improves outcomes in depression and depressive disorders. Results …
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: Treatment of Depressive Symptoms in Breast Cancer Patients: Comparison of Cognitive Therapy and Bright Light Therapy [NA]
This clinical trial compared cognitive therapy and bright light therapy for depressive symptoms in breast cancer patients. The study has com…
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CLINICAL_TRIALS trial_result · 2016-04-21Clinical Trial Update: Comorbidities and Virologic Outcome Among Patients on Anti-retroviral Therapy in Rural Lesotho
This completed trial from rural Lesotho studied how comorbidities such as metabolic syndrome, depression, alcoholism, and hepatitis affect v…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Correlating Real and Virtual World Behavioral Fluctuations in Adolescence
A completed clinical trial update examining associations between real-world and virtual-world behaviors in adolescents, focusing on attentio…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Buprenorphine for Treatment Resistant Depression [Phase 3]
Phase 3 trial evaluating buprenorphine for treatment-resistant depression has completed. Results were posted in March 2016.
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Health Care Management for the Elderly in Community Through Screening [NA]
This clinical trial update notes completion of a study on elderly community health management through screening, focusing on major depressiv…