Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: Ketamine and Postoperative Depressive Symptom-PASSION [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial investigating ketamine for depressive symptoms in the perioperative/postoperative setting has completed.
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CLINICAL_TRIALS trial_result · 2020-04-30Clinical Trial Update: Pharmacogenomic Decision Support With GeneSight Psychotropic to Guide the Treatment of Major Depressive Disorder [Phase 4]
Phase 4 trial update evaluating Pharmacogenomic Decision Support with GeneSight Psychotropic to guide treatment of major depressive disorder…
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: Intramuscular Ketamine Versus Aripiprazole and Escitalopram in the Treatment of Resistant Depression [Phase 4]
A Phase 4 clinical trial comparing intramuscular ketamine to aripiprazole and escitalopram for treatment-resistant depression is ongoing, wi…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Ketamine for Relapse Prevention in Recurrent Depressive Disorder [Phase 1]
Phase 1 clinical trial evaluating ketamine for relapse prevention in recurrent depressive disorder has been terminated with posted results.
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CLINICAL_TRIALS trial_result · 2019-12-04Clinical Trial Update: Melancholic Depression and Insomnia as Predictors of Response to Quetiapine in Patients With Major Depression [Phase 4]
Phase 4 trial looking at melancholic depression and insomnia as predictors of response to quetiapine in patients with major depressive disor…
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CLINICAL_TRIALS trial_result · 2019-10-14Clinical Trial Update: Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine [Phase 4]
Phase 4 clinical trial update on vortioxetine focusing on pattern separation, brain-derived neurotrophic factors, and mechanisms; trial term…
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: TMS for Adults With Autism and Depression [NA]
Clinical trial of transcranial magnetic stimulation (TMS) in adults with autism and depression has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-20Clinical Trial Update: EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy [NA]
Clinical trial update for EnBrace HR evaluating depression treatment and prevention in women attempting conception and during early pregnanc…
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: The Effect of Attention Bias Modification Training on Reducing Depressive Symptoms [NA]
A completed clinical trial evaluating whether Attention Bias Modification Training reduces depressive symptoms.
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: Effects of Therapist Behavior on the Treatment of Depressed Adolescents [Phase 1, Phase 2]
A completed phase 1/2 clinical trial evaluating how therapist behavior influences treatment outcomes in depressed adolescents.
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: Integrated Intervention for Substance Abusers With Depressive Disorders [Phase 2]
Phase 2 clinical trial update for an integrated intervention targeting substance-related disorders with co-occurring depressive disorders; s…
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: TAK-653 Escalating Single and Multiple Dose Study in Healthy Participants [Phase 1]
Phase 1 trial update for TAK-653 in healthy participants completed, with results posted.
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Acute Aerobic Exercise and Neuroplasticity in Depression [NA]
Completed clinical trial evaluating whether acute aerobic exercise affects neuroplasticity in individuals with depression.
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CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: A Multicenter, Relapse Prevention Study With Levomilnacipran Extended Release (ER) in Participants With Major Depressive Disorder [Phase 4]
Phase 4 clinical trial update on relapse prevention with levomilnacipran ER in adults with major depressive disorder; results posted after c…
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CLINICAL_TRIALS trial_result · 2018-10-19Clinical Trial Update: A Study to Evaluate the Effect of Activated Charcoal on the Absorption of LY2216684 in Healthy Subjects [Phase 1]
Phase 1 study assessing the effect of activated charcoal on absorption of LY2216684 in healthy subjects completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) [Phase 3]
Phase 3 trial update on the safety and tolerability of oral OPC-34712 as an adjunctive therapy for adults with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress [Phase 3]
Phase 3 study evaluating fixed-dose brexpiprazole as adjunctive therapy in adults with major depressive disorder with and without anxious di…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects [Phase 1]
Phase 1 repeat-dose study evaluating safety and pharmacokinetics of controlled-release and immediate-release paroxetine tablets in healthy J…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects [Phase 1]
Phase 1 single-dose pharmacokinetic study of controlled-release paroxetine tablets in healthy Japanese male subjects has completed.
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders [Phase 1]
A Phase 1 outpatient trial for adolescents with comorbid substance use and internalizing disorders has completed.
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CLINICAL_TRIALS trial_result · 2018-06-11Clinical Trial Update: Effectiveness of Non-medical Health Worker (NMHW) Led Counseling on Common Mental Disorders in Rural Mid-western Nepal [NA]
A completed clinical trial evaluated the effectiveness of non-medical health worker–led counseling for common mental disorders in rural Mid-…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Family Based Treatment of Depressed Adolescents (AHUS) [NA]
The clinical trial evaluating family-based treatment for depressed adolescents (AHUS) has been terminated.
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: MDD POC Study GSK372475 Subjects Depressive Disease [Phase 2]
Phase 2 trial update for GSK372475 in depressive disorder shows completed status with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Text-Message-Based Depression Prevention for High-Risk Youth in the ED [NA]
Completed clinical trial evaluating text-message-based depression prevention for high-risk youth in the emergency department; results posted…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Treatment Outcome of Vascular Depression
This completed University of Pennsylvania trial reports the treatment outcomes for vascular depression.