Dental Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment [Phase 4]
A Phase 4 clinical trial evaluated the efficacy of trypsin-chymotrypsin on post-operative pain after single-visit root canal treatment; stud…
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CLINICAL_TRIALS research · 2023-06-18Clinical Trial Update: Impact of Tramadol Addiction On Dental Anesthesia Success [Phase 4]
Phase 4 clinical trial exploring how tramadol addiction affects success of dental anesthesia.
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CLINICAL_TRIALS trial_result · 2023-02-09Clinical Trial Update: Phase III Efficacy and Tolerability Trial of the Fixed Dose Combination of Etodolac 400 mg and Cyclobenzaprine 10 mg Versus Isolated Active Substances in Pain Control After Impacted Third Molar Extraction [Phase 3]
A Phase III trial evaluating a fixed-dose combination of etodolac and cyclobenzaprine versus individual components for pain control after im…
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: A Study of Acetaminophen for Post Surgical Dental Pain [Phase 2]
Phase 2 trial of acetaminophen for post-surgical dental pain completed; results posted in 2022.
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FDA approval · 2022-01-11FDA Approved: CELECOXIB — Supplemental Application (NIVAGEN PHARMACEUTICALS, INC.)
The FDA approved a supplemental application for Celecoxib submitted by NIVAGEN Pharmaceuticals, Inc., for a generic Celecoxib product.
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FDA approval · 2022-01-05FDA Approved: CELECOXIB — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' supplemental application for a generic celecoxib product (Celecoxib) under ANDA 202240.
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CLINICAL_TRIALS trial_result · 2021-12-03Clinical Trial Update: Study of Acetaminophen (ACE) in Post-operative Dental Pain [Phase 2]
Phase 2 clinical trial update for acetaminophen (ACE) in post-operative dental pain is completed.
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CLINICAL_TRIALS trial_result · 2021-11-23Clinical Trial Update: Dental Pain Study of Analgesics in Patients Undergoing Molar Removal [Phase 2]
Phase 2 clinical trial update for analgesics in dental pain after molar extraction; results completed and posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction [Phase 2]
A Phase 2 clinical trial evaluating ARRY-371797 in adults undergoing third molar extraction for dental pain has completed.
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CLINICAL_TRIALS trial_result · 2021-02-09Clinical Trial Update: A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction [Phase 2]
Phase 2 study of ARRY-371797 in adults undergoing third molar extraction for dental pain has completed.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction [Phase 3]
A Phase 3 clinical trial evaluating EXPAREL for prolonged postoperative analgesia in third molar extraction was completed with results poste…
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CLINICAL_TRIALS trial_result · 2020-10-05Clinical Trial Update: The Impact of Minimally Invasive Restorative Techniques on Dental Pain in Pregnant Women [Phase 2]
Phase 2 trial evaluating minimally invasive restorative techniques and their effect on dental pain in pregnant women has completed.
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CLINICAL_TRIALS trial_result · 2020-03-04Clinical Trial Update: Nonpharmacologic Reduction of Periprocedural Distress and Drug Use [NA]
A completed clinical trial evaluating nonpharmacologic methods to reduce periprocedural distress and drug use in dental procedures.
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FDA approval · 2019-12-03FDA Approved: DICLOFENAC POTASSIUM — Original Application (Lifsa Drugs LLC)
FDA approved the original application for diclofenac potassium as a generic NSAID for relief of pain and inflammation associated with variou…
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CLINICAL_TRIALS trial_result · 2019-06-06Clinical Trial Update: Role of Propolis Paste in Preventing Pain After Root Canal Treatment. [Phase 3]
Phase 3 clinical trial assessing propolis paste to prevent postoperative pain after root canal treatment has been completed; results posted …
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CLINICAL_TRIALS trial_result · 2019-04-12Clinical Trial Update: Effectiveness and Safety of Different Doses of BI 1026706 in Patients With Postoperative Dental Pain [Phase 1]
A Phase 1 clinical trial assessing effectiveness and safety of different doses of BI 1026706 in patients with postoperative dental pain has …
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Evaluation of Articaine 4% Versus Mepivacaine 2% for Surgery of Molars Thirds: Clinical Trial. [NA]
Completed clinical trial comparing articaine 4% versus mepivacaine 2% for anesthesia in third molar surgery, including cases with impacted t…
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain [Phase 2]
Phase 2 trial updating efficacy of an anti-inflammatory block injection for mandibular dental pain due to symptomatic irreversible pulpitis …
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CLINICAL_TRIALS trial_result · 2018-12-06Clinical Trial Update: Maxigesic 325 Acute Dental Pain Study [Phase 3]
Phase 3 clinical trial update for Maxigesic 325 in acute dental pain has completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study [Phase 3]
Phase 3 clinical trial comparing ibuprofen/acetaminophen combination with Nurofen Plus and Panadeine Extra for post-operative dental pain; s…
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CLINICAL_TRIALS trial_result · 2018-03-05Clinical Trial Update: A Study of Ibuprofen (IBU) 250mg/APAP 500mg In The Treatment Of Post-Surgical Dental Pain [Phase 3]
Pfizer conducted a Phase 3 trial evaluating a fixed-dose combination of ibuprofen 250 mg and acetaminophen 500 mg for post-surgical dental p…
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CLINICAL_TRIALS research · 2017-05-31Clinical Trial Update: Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth [NA]
A clinical trial evaluating whether preemptive intravenous ibuprofen can reduce intraoperative analgesia needs during third molar tooth extr…
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CLINICAL_TRIALS trial_result · 2016-11-16Clinical Trial Update: Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain [Phase 3]
Phase 3 trial update evaluating the efficacy and safety of ibuprofen combined with caffeine for postoperative dental pain; results have been…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Acute Toothache Patients After Teeth Extraction Surgery [Phase 3]
Phase 3 study evaluating tramadol hydrochloride/acetaminophen formulations for acute dental pain after tooth extraction has completed.
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FDA approval · 2016-09-02FDA Approved: DICLOFENAC SODIUM — Original Application (SOLA Pharmaceuticals, LLC)
FDA approved SOLA Pharmaceuticals' diclofenac sodium tablet as an original generic, indicated for relief of pain and inflammation in conditi…