Dengue Fever
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Surveillance of Suspected Dengue Cases for Access to Care for Subjects Identified as Seronegative or Undetermined Before Receiving CYD Dengue Vaccine in Previous Clinical Studies in Colombia
An ongoing surveillance update in Colombia assessing suspected dengue cases to ensure access to care for participants who were seronegative …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Prospective Clinical Registry for Evaluation of Exanthematous Infections and Coinfections
A prospective clinical registry evaluating exanthematous infections and coinfections, including dengue fever, chikungunya, measles, and rube…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Efficacy of Dengue Infection With Warning Signs Treated With Dexamethasone (DengDex Study) [NA]
A clinical trial is evaluating dexamethasone for severe dengue with warning signs; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Zanamivir Treatment of Vascular Permeability in Dengue (ZAP-DENGUE) [Phase 2]
Phase 2 clinical trial evaluating zanamivir for treatment of dengue-related vascular permeability; currently recruiting.
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: A Study of 2 Doses of Tetravalent Dengue Vaccine (TDV) in Infants and Toddlers [Phase 3]
A Phase 3 study evaluating two doses of the tetravalent dengue vaccine (TDV) in infants and toddlers is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: The Comparative Efficacy of Standard Treatment Plus Ribavirin vs Standard Treatment Alone in Preventing Clinically Significant Hemorrhage in Patients With Dengue Fever [Phase 3]
Phase 3 randomized trial evaluating whether adding ribavirin to standard dengue treatment reduces clinically significant hemorrhage compared…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Long-Term Safety and Antibody Persistence of TDV and the Impact of a Booster Dose [Phase 3]
Phase 3 study evaluating long-term safety and antibody persistence of the Takeda dengue vaccine (TDV) and the impact of a booster dose, with…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: A Study to Monitor the Adverse Events of QDENGA Vaccine in Participants in Malaysia
A clinical trial update describing monitoring of adverse events for the QDENGA dengue vaccine in participants in Malaysia, sponsored by Take…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Effectiveness Evaluation of the "Mosquito-Free Campus" Initiative on Dengue Fever Prevention and Control: A Cluster Randomized Controlled Trial [NA]
This cluster randomized trial will evaluate the effectiveness of a 'Mosquito-Free Campus' initiative in preventing dengue fever, though part…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Molecular and Cellular Basis of Severe Forms of Dengue in Sickle Cell Patients
A clinical trial investigating the molecular and cellular basis of severe dengue in patients with sickle cell disease, currently recruiting.
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Characterisation of Dengue Vaccine-induced Specific Immunity in Vaccinees With and Without Prior Exposure to Flavivirus Infections or Vaccination
This clinical trial characterises the immune response induced by a dengue vaccine in participants with and without prior flavivirus exposure…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Safety and Immunogenicity of Three V181 Dengue Vaccine Potencies in Adults (V181-003) [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of three potencies of the V181 dengue vaccine in adults; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Effects of Carica Papaya Leaf Extract (CPLE) in the Outcome of Hospitalized Dengue Patients [Phase 1, Phase 2]
Phase 1/2 clinical trial update assessing the effects of Carica papaya leaf extract (CPLE) in hospitalized dengue patients; the study has be…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge [Phase 2]
Phase 2 trial evaluating repeated oral doses of JNJ-64281802 against Dengue virus serotype 3 has completed, with results posted.
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Characteristics of Clinical Laboratory Indicators in Patients with Dengue Fever
A completed clinical study examining laboratory indicators observed in patients with dengue fever to characterize common lab patterns.
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Safety and Immunogenicity of the Dengue Virus Vaccine TV005 (TetraVax-DV TV005) in Healthy Adults, Adolescents, and Children in Dhaka, Bangladesh [Phase 2]
Phase 2 study assessing safety and immunogenicity of the dengue vaccine TV005 (TetraVax-DV TV005) in healthy adults, adolescents, and childr…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Efficacy of Fresh Frozen Plasma (FFP) in Treating Thrombocytopenia in Dengue Patients [NA]
This entry provides an update on a clinical trial evaluating the efficacy of fresh frozen plasma for dengue-associated thrombocytopenia; the…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Cohort Event Monitoring for Dengvaxia®, CYD-TDV Dengue Vaccine
This document reports the completion of a cohort event monitoring study for Dengvaxia (CYD-TDV) dengue vaccine, describing safety observatio…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Factors Associated With Hospitalization for Dengue and Dengue Severity: Hospital-based Cohort Study on Reunion Island [NA]
This hospital-based cohort study on Reunion Island analyzes factors associated with hospitalization and severity of dengue infection in pati…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Safety and Immunogenicity of a Tetravalent Dengue Vaccine in HIV-Positive Adults [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of a tetravalent dengue vaccine in HIV-positive adults; results completed and posted in J…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Dengue Controlled Human Infection Model in Dhaka, Bangladesh [Phase 2]
A Phase 2 dengue controlled human infection model trial in Dhaka, Bangladesh, currently not recruiting.
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Genetic Evolution of Arboviruses in New Caledonia Between 1995 and 2024 and Impact of Wolbachia
A clinical trial in New Caledonia studying the genetic evolution of dengue, Zika, and chikungunya viruses from 1995–2024 and assessing the i…
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: Population Immunity AgaiNst mosquitO-borne Diseases in Vanuatu [NA]
A clinical trial evaluating population immunity to multiple mosquito-borne diseases in Vanuatu has completed, covering Zika virus disease, d…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Virological and Immunological Determinants of Arbovirus Infection in New Caledonia [NA]
Clinical trial update from Institut Pasteur in New Caledonia studying virological and immunological determinants of arbovirus infections, in…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Sustainable Reduction of Dengue in Colombia: Vector Breeding Site Intervention With an Insecticidal Coating [NA]
Colombia-based clinical trial evaluating an insecticidal coating applied at vector breeding sites to sustainably reduce dengue and related a…