Delirium
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: High Spinal Anesthesia and the Incidence of Delirium After Cardiac Surgery [NA]
This update reports on a clinical trial evaluating whether high spinal anesthesia influences the incidence of postoperative delirium in pati…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Occupational Therapy Intervention on the Prevention of Delirium and Occupational Performance Status in Elderly Patients [NA]
A not-yet-recruiting study evaluating whether an occupational therapy program can prevent delirium and improve occupational performance in e…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Electroencephalography and Sleep Quality With Lormetazepam in the Intensive Care Unit
A clinical trial conducted by Charite University in Berlin is evaluating electroencephalography and sleep quality with lormetazepam in ICU p…
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: The Use of PARO to Decrease Agitation in Persons With Dementia and/or Delirium [NA]
This update covers completion of a clinical trial evaluating the PARO robotic seal to decrease agitation in persons with dementia and/or del…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients [NA]
The trial investigates the impact of desflurane and sevoflurane on postoperative delirium and cognitive dysfunction in elderly patients and …
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: The Effect of Lavender Essential Oil for Delirium in Elderly Intensive Care Unit Patients: Study Protocol [NA]
A study protocol investigating whether lavender essential oil can reduce delirium in elderly ICU patients. The trial is currently recruiting…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Efficacy and Safety of Suvorexant (MK-4305) for Reducing Incidence of Delirium in Japanese Participants at High Risk of Delirium (MK-4305-085) [Phase 3]
Phase 3 trial assessing whether suvorexant (MK-4305) reduces the incidence of delirium in Japanese individuals at high risk; results and saf…
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CLINICAL_TRIALS withdrawal · 2024-05-13Clinical Trial Update: Dexmedetomidine Sublingual Film for the Management of Agitation in Delirium: Safety and Preliminary Efficacy [Phase 2]
A Phase 2 trial evaluating a dexmedetomidine sublingual film for agitation in delirium was withdrawn.
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Wearable Sensors for Delirium Detection at an Early Stage (WeSen_delirium)
The University of Zurich is conducting a clinical trial evaluating wearable sensors to detect delirium at an early stage; the study is curre…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Combined Activity and Cognitive Intervention for ICU Survivors [NA]
A University of Hong Kong-led clinical trial is enrolling by invitation to test a combined physical activity and cognitive intervention for …
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) [Phase 4]
Phase 4 randomized clinical trial comparing trazodone, quetiapine, and placebo for ICU delirium; status not yet recruiting.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Trazodone vs. Quetiapine for the Treatment of ICU Delirium
A USC-sponsored clinical trial is evaluating trazodone versus quetiapine for ICU delirium and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Study to Identify the Incidence of Post Traumatic Stress Symptoms in Patients With Delirium Following Cardiac Surgery
This completed clinical trial investigated the incidence of post-traumatic stress symptoms in patients who developed delirium after cardiac …
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CLINICAL_TRIALS guidance · 2024-05-07Clinical Trial Update: Delirium Prevention Guideline for Intensive Care Patients [NA]
The document describes a delirium prevention guideline for intensive care unit patients, highlighting the nurse's role in prevention strateg…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: Family Caregiver Role in Decreasing Delirium in Older Patients With Fractured Femur Using HELP Principles. [NA]
A clinical trial is examining whether family caregiver support using HELP principles decreases delirium in older patients with femoral fract…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Music Therapy as a Treatment for Delirium in Acutely Hospitalized Older Patients [NA]
A completed clinical trial evaluating music therapy as a treatment for delirium in acutely hospitalized older patients.
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery [Phase 4]
Phase 4 study investigating infusion of dexmedetomidine or clonidine to prevent delirium after open-heart surgery; the trial is currently re…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: The Effect of Guanfacine on Delirium in Critically Ill Patients [Phase 3]
Phase 3 trial evaluating guanfacine for delirium in critically ill patients has completed, with results posted in 2024-04-17. The sponsor is…
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FDA approval · 2024-04-11FDA Approved: HALOPERIDOL — Original Application (Lifestar Pharma LLC)
FDA approved a generic haloperidol product from Lifestar Pharma LLC under an Original Application (ANDA 216918).
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU [Phase 4]
A Phase 4 clinical trial evaluated the effect of ramelteon on delirium and sleep in ICU patients and has completed.
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: Improving the Recovery and Outcome Every Day After the ICU [NA]
Completed clinical trial related to recovery and outcomes after ICU stay; conditions include delirium and Alzheimer disease, with results po…
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: Safety and Efficacy Evaluation of S (+) - Ketamine in Children [Phase 4]
A Phase 4 clinical trial assessing safety and efficacy of S(+)-ketamine in children for acute postoperative analgesia and related outcomes i…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: IV Acetaminophen After Cardiac Surgery - PILOT [Phase 3]
A Phase 3 clinical trial investigating intravenous acetaminophen after cardiac surgery for delirium is underway (pilot status unknown).
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CLINICAL_TRIALS research · 2024-02-21Clinical Trial Update: Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR) [NA]
Clinical trial RADAR study investigating delirium alleviation with real-time alerting; status completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department
A completed clinical trial from Yale University exploring detection and differentiation of delirium and dementia in emergency department set…