Degenerative Disc Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: ACDF Using Structural Allograft vs. Tritanium C [NA]
This clinical trial compares anterior cervical discectomy and fusion using structural allograft versus a Tritanium C cage for degenerative d…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD [NA]
Clinical trial update on the Posterior Cervical Stabilization System (PCSS) used with circumferential fusion to treat multilevel degenerativ…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Retro Comparison of Subsidence Following Interbody Devices in Lumbar Spine
This clinical trial compares subsidence between lumbar interbody devices for degenerative disc disease and has completed.
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Single Position Spine Surgery Registry
A terminated clinical trial registry study of single-position spine surgery, covering spine fusion, spinal stenosis, and degenerative disc d…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: OssiMend BA in Posterolateral Instrumented Lumbar Fusion
Clinical trial update for OssiMend BA in posterolateral instrumented lumbar fusion shows the study is currently recruiting for spinal diseas…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Natural Matrix Protein™ (NMP™) in Interbody Lumbar Fusion
A clinical trial evaluating Natural Matrix Protein (NMP) for interbody lumbar fusion in degenerative disc disease has completed.
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Comparison of Posterior Cellular Bonegraft Options for Single Level Lumbar Spinal Fusion [Phase 2, Phase 3]
The document reports the completion of Phase 2 and Phase 3 trials comparing posterior cellular bone graft options for single-level lumbar sp…
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CLINICAL_TRIALS withdrawal · 2025-10-07Clinical Trial Update: Stem Cells vs. Steroids for Discogenic Back Pain [NA]
This clinical trial comparing stem cell therapy to steroid treatment for discogenic back pain has been withdrawn. The studied conditions are…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation [NA]
Clinical trial update for the P-15L Bone Graft used in transforaminal lumbar interbody fusion with instrumentation, sponsored by Cerapedics,…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Investigation of DEXA-C Anterior Cervical Interbody System [NA]
The DEXA-C Anterior Cervical Interbody System study is currently recruiting for patients with degenerative disc disease.
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Efficacy of Intradiscal Injection of BM-MSC in Subjects With Chronic Low Back Pain (LBP) Due to Lumbar Degenerative Disc Disease (DDD) Unresponsive [Phase 2, Phase 3]
Clinical trial update on intradiscal injection of bone marrow-derived mesenchymal stem cells for chronic low back pain due to degenerative d…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: The Course of Hip Flexion Weakness Following LLIF or ALIF
This clinical trial update describes the course of hip flexion weakness following lateral lumbar interbody fusion (LLIF) or anterior lumbar …
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF [Phase 4]
A Phase 4 trial is evaluating preemptive intravenous dexamethasone for efficacy and safety in MIS-TLIF for lumbar spinal stenosis and degene…
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CLINICAL_TRIALS withdrawal · 2025-09-05Clinical Trial Update: Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion Device
The postmarket clinical follow-up study of the Arcadius XP L interbody fusion device has been withdrawn, with listed indications including c…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
This is an ongoing clinical trial comparing SeaSpine Shoreline adjacent level anterior cervical fusion versus removal of a previously implan…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Study to Assess the Performance of MagnEtOs Flex Matrix Compared to Cellular Allograft
This clinical trial update describes a study comparing MagnEtOs Flex Matrix to a cellular allograft for degenerative disc disease; recruitme…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Investigation of miRNA Expression Profiles in Human Degenerated Intervertebral Disc Tissues [NA]
A non-recruiting clinical trial at Çanakkale Onsekiz Mart University investigates microRNA expression profiles in human degenerated interver…
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CLINICAL_TRIALS withdrawal · 2025-07-31Clinical Trial Update: Effect of RECK in Posterior Spinal Fusion [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating RECK in posterior spinal fusion has been withdrawn, including conditions such as degenerative lumbar s…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Clinical Outcome and Fusion Rate of 3D Printed Interbody Fusion Cages and Titanium Coated PEEK Cages
This clinical trial update reports outcomes and fusion rates for 3D-printed interbody fusion cages compared with titanium-coated PEEK cages …
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease [NA]
A completed clinical trial evaluated ViviGen for lumbar degenerative disc disease, with results posted in June 2025.
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Clinical Decision-Making and Virtual Reality Exercise [NA]
This clinical trial update reports the completion of a study evaluating clinical decision-making and virtual reality exercise for degenerati…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: PMCF Neo Pedicle Screw and Cage Systems
This clinical trial update concerns the PMCF Neo Pedicle Screw and Cage Systems study (NCT03956537), noting the trial is currently active bu…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Comparison of Radiographic Fusion Rate and Clinical Outcome of ALIF and XLIF Performed With Either Recombinant Human Bone Morphogenetic Protein-2 or ViviGen® [NA]
This clinical trial, currently recruiting, compares radiographic fusion rate and clinical outcomes of ALIF and XLIF procedures using either …
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Safety Study for An Artificial Disc Nucleus Replacement to Treat Chronic Low Back Pain [NA]
A safety study of an artificial disc nucleus replacement for chronic low back pain sponsored by Spinal Stabilization Technologies has been t…
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CLINICAL_TRIALS withdrawal · 2025-05-21Clinical Trial Update: Post Market Observational Trial for the PerQdisc Nucleus Replacement Device
Post-market observational trial NCT05105490 evaluating the PerQdisc Nucleus Replacement Device has been withdrawn.