Degenerative Disc Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: 3D Biomimetic Spine Unit Model Through the Integration of Bioprinting and Transcriptomics (CDP-SUBT)
This recruiting study, sponsored by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio, investigates a 3D biomimetic spine unit model created via bio…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion
An ongoing trial is evaluating Natural Matrix Protein Fibers for cervical and lumbar interbody fusion in degenerative spine conditions. Enro…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: ACDF Using Structural Allograft vs. Tritanium C [NA]
This clinical trial compares anterior cervical discectomy and fusion using structural allograft versus a Tritanium C cage for degenerative d…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD [NA]
Clinical trial update on the Posterior Cervical Stabilization System (PCSS) used with circumferential fusion to treat multilevel degenerativ…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Single Position Spine Surgery Registry
A terminated clinical trial registry study of single-position spine surgery, covering spine fusion, spinal stenosis, and degenerative disc d…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: OssiMend BA in Posterolateral Instrumented Lumbar Fusion
Clinical trial update for OssiMend BA in posterolateral instrumented lumbar fusion shows the study is currently recruiting for spinal diseas…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation [NA]
Clinical trial update for the P-15L Bone Graft used in transforaminal lumbar interbody fusion with instrumentation, sponsored by Cerapedics,…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Efficacy of Intradiscal Injection of BM-MSC in Subjects With Chronic Low Back Pain (LBP) Due to Lumbar Degenerative Disc Disease (DDD) Unresponsive [Phase 2, Phase 3]
Clinical trial update on intradiscal injection of bone marrow-derived mesenchymal stem cells for chronic low back pain due to degenerative d…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: The Course of Hip Flexion Weakness Following LLIF or ALIF
This clinical trial update describes the course of hip flexion weakness following lateral lumbar interbody fusion (LLIF) or anterior lumbar …
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF [Phase 4]
A Phase 4 trial is evaluating preemptive intravenous dexamethasone for efficacy and safety in MIS-TLIF for lumbar spinal stenosis and degene…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
This is an ongoing clinical trial comparing SeaSpine Shoreline adjacent level anterior cervical fusion versus removal of a previously implan…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Study to Assess the Performance of MagnEtOs Flex Matrix Compared to Cellular Allograft
This clinical trial update describes a study comparing MagnEtOs Flex Matrix to a cellular allograft for degenerative disc disease; recruitme…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Investigation of miRNA Expression Profiles in Human Degenerated Intervertebral Disc Tissues [NA]
A non-recruiting clinical trial at Çanakkale Onsekiz Mart University investigates microRNA expression profiles in human degenerated interver…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: PMCF Neo Pedicle Screw and Cage Systems
This clinical trial update concerns the PMCF Neo Pedicle Screw and Cage Systems study (NCT03956537), noting the trial is currently active bu…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Comparison of Radiographic Fusion Rate and Clinical Outcome of ALIF and XLIF Performed With Either Recombinant Human Bone Morphogenetic Protein-2 or ViviGen® [NA]
This clinical trial, currently recruiting, compares radiographic fusion rate and clinical outcomes of ALIF and XLIF procedures using either …
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Trial for Treating Painful Degenerative Disc Disease [NA]
A Regenexx, LLC-sponsored clinical trial for treating Degenerative Disc Disease is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: ASCEND: A Clinical Trial to Evaluate the Safety and Effectiveness of VIA Disc NP, a Supplement for Degenerated Intervertebral Discs [Phase 2]
The ASCEND trial is a Phase 2 study evaluating the safety and effectiveness of VIA Disc NP for degenerative disc disease, with recruitment c…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft. [NA]
Clinical trial update comparing NanoBone synthetic bone graft to local autologous bone graft for spinal fusion in degenerative disc disease …
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine. [NA]
This clinical trial update describes an ongoing study evaluating the safety and effectiveness of a hybrid construct using the Mobi-C cervica…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Carbofix Pedicle Screw System: Evaluation of the Clinical and Radiographic Outcomes of the Use of a Carbon Fiber Device Compared to Titanium Devices in Patients Undergoing Spinal Arthrodesis for Degenerative Spinal Diseases [NA]
Clinical trial evaluating carbon fiber Carbofix pedicle screw system versus titanium screws for spinal fusion in degenerative spine diseases…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Study to Determine the Safety and Tolerability of TG-C in Subjects with Back Pain Due to Degenerative Disc Disease [Phase 1]
This clinical trial update announces a Phase 1 study to assess the safety and tolerability of TG-C in back pain due to degenerative disc dis…
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: Personalized Spine Study Group (PSSG) Registry
This is a registry entry for the Personalized Spine Study Group (PSSG) Registry sponsored by the University of Colorado, Denver. It is curre…
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Spine Unit Modelling Coupled With hIgh Throughput Analysis (SUIT)
Clinical trial update for the SUIT study, which evaluates spine unit modeling coupled with high-throughput analysis. The trial addressing de…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases [NA]
A clinical trial comparing mid- or high-flex rods to low-flex rods in the SpineShape System IV for degenerative lumbar spine diseases is cur…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Evaluating the Efficacy of Para-discal Infiltration in Patients With Lateralized MODIC 1 Inflammatory Disc Disease [NA]
This document provides an update on an ongoing clinical trial evaluating para-discal infiltration for lateralized MODIC type 1 inflammatory …