Cutaneous T-cell Lymphoma
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment
NCI-sponsored clinical trial update describes collecting human samples to study hairy cell leukemia and other leukemias, and to develop reco…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Epidemiology and Management of Cutaneous T-Cell Lymphoma at Hospital México, Costa Rica.
This document provides an update on an ongoing clinical trial in Costa Rica examining the epidemiology and management of Cutaneous T-Cell Ly…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma [Phase 1]
A first-in-human Phase 1 study of KK2223 in relapsed or refractory T-cell non-Hodgkin lymphoma (PTCL or CTCL) is planned, with the trial cur…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Aclarubicin Plus Cyclophosphamide, Vincristine, and Prednisone (CAOP) in Patients With Previously Treated Cutaneous T-cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Aclarubicin in combination with cyclophosphamide, vincristine, and prednisone (CAOP) in patients with …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma [Phase 2]
An ongoing Phase 2 study evaluating maintenance therapy with ruxolitinib after hematopoietic stem cell transplant in patients with T-cell ly…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIA [Phase 2]
Phase 2 trial evaluating the safety and efficacy of 2% topical tofacitinib cream for cutaneous T-cell lymphoma (CTCL) at stages IA-IIA is cu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Anti-ICOS Monoclonal Antibody MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma [Phase 1]
This clinical trial update discusses MEDI-570, an anti-ICOS monoclonal antibody, in relapsed or refractory peripheral T-cell lymphoma follic…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Mogamulizumab and Brentuximab Vedotin in CTCL and Mycosis Fungoides [Phase 1]
This clinical trial update describes a Phase 1 study evaluating mogamulizumab and brentuximab vedotin in patients with cutaneous T-cell lymp…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL [Phase 1]
Phase 1 study evaluating pembrolizumab in combination with decitabine and pralatrexate for peripheral T-cell lymphoma and cutaneous T-cell l…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL [Phase 3]
A Phase 3 confirmatory study of topical HyBryte versus placebo for cutaneous T-cell lymphoma (CTCL) is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies [Phase 1]
Phase 1 trial evaluating an anti-CD30 bispecific antibody (AATC) in relapsed/refractory CD30-positive hematologic malignancies; currently re…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Ropeginterferon in Patients w/Cutaneous T-Cell Lymphoma (CTCL) [Phase 1]
Phase 1 clinical trial evaluating Ropeginterferon in patients with cutaneous T-cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL [Phase 2]
An ongoing Phase 2 study of PTX 100 in relapsed/refractory cutaneous T-cell lymphoma (CTCL) is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies [Phase 1, Phase 2]
A first-in-human study evaluating HLA partially to fully matched allogeneic, cryopreserved deceased donor bone marrow transplantation for va…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) [Phase 1]
A Phase 1 clinical trial is evaluating CCR4-directed CAR T cells in CCR4-expressing mature T-cell malignancies, including peripheral T-cell …
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma [Phase 1]
A Phase 1 trial evaluating third-party allogeneic natural killer cells together with mogamulizumab for relapsed or refractory adult T-cell l…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Phase IIa Clinical Study of Purinostat Mesylate for Injection in Patients With Peripheral T-Cell Lymphoma and Cutaneous T-Cell Lymphoma [Phase 2]
Phase IIa clinical trial update for Purinostat Mesylate for Injection in relapsed or refractory peripheral T-cell lymphoma and cutaneous T-c…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study of Bexarotene Combined With Radiotherapy in People With Mycosis Fungoides [Phase 1]
Phase 1 trial evaluating the safety of combining Bexarotene with radiotherapy in patients with Mycosis Fungoides, a form of cutaneous T-cell…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Quality of Life in Cutaneous Lymphoma Patients Using the Skindex29
A clinical trial is recruiting to evaluate quality of life in patients with cutaneous T-cell lymphoma using the Skindex-29 instrument.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Pembrolizumab and Mogamulizumab in Advanced-stage, Relapsed/Refractory Cutaneous T-cell Lymphomas [Phase 2]
Phase 2 clinical trial update evaluating pembrolizumab with mogamulizumab in advanced-stage, relapsed/refractory cutaneous T-cell lymphoma, …
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL [Phase 1]
Phase 1 study of CAR-T cells targeting CD30 and CCR4 for relapsed/refractory CD30+ Hodgkin lymphoma and cutaneous T-cell lymphoma, with the …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
This clinical trial update indicates ongoing recruitment for a University of Pittsburgh study collecting blood, urine, and tissue samples fr…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Amping up With PemJAK [Phase 2]
A Phase 2 clinical trial of PemJAK for multiple lymphoma subtypes is currently recruiting, including non-Hodgkin lymphoma and Hodgkin lympho…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Systemic Therapies in the Treatment of Cutaneous T-cell Lymphoma
A clinical trial update notes ongoing recruitment for systemic therapies in the treatment of cutaneous T-cell lymphoma, including mycosis fu…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: JAK1 Inhibitor Golidocitnib for the Treatment of Relapsed/Refractory Indolent T/NK-cell Lymphomas [Phase 2]
Clinical trial update indicates a Phase 2 study of the JAK1 inhibitor golidocitnib for relapsed/refractory indolent T- and NK-cell lymphomas…