Cutaneous Leishmaniasis
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CLINICAL_TRIALS trial_result · 2013-11-18Clinical Trial Update: A Study of the Efficacy and Safety of the LEISH-F2 + MPL-SE Vaccine for Treatment of Cutaneous Leishmaniasis [Phase 2]
Phase 2 study evaluating the LEISH-F2 vaccine with MPL-SE adjuvant for treating cutaneous leishmaniasis has completed, with results posted i…
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CLINICAL_TRIALS trial_result · 2012-12-06Clinical Trial Update: Safety, False-Positive Reactions and Sensitizing Properties of Leishmania Tropica Skin Test Antigen [Phase 2]
Phase 2 trial assessing safety, false-positive reactions, and sensitizing properties of Leishmania tropica skin test antigen in cutaneous le…
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CLINICAL_TRIALS trial_result · 2012-09-03Clinical Trial Update: Efficacy of Radio-frequency Induced Heat (RFH)Therapy in Treatment of Cutaneous Leishmaniasis in India [Phase 4]
A Phase 4 clinical trial in India completed evaluating the efficacy of radio-frequency induced heat therapy for cutaneous leishmaniasis. The…
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CLINICAL_TRIALS trial_result · 2012-06-20Clinical Trial Update: Efficacy of Topical Liposomal Form of Drugs in Cutaneous Leishmaniasis [EARLY_Phase 1]
An early-phase 1 study assessed the efficacy of a topical liposomal formulation for cutaneous leishmaniasis and has completed. The update su…
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CLINICAL_TRIALS trial_result · 2011-09-20Clinical Trial Update: Efficacy Trial on Oral Miltefosine in Comparison With Glucantime in the Treatment of ACL Caused by L. Tropica [Phase 3]
A Phase 3 efficacy trial comparing oral miltefosine with Glucantime for cutaneous leishmaniasis caused by Leishmania tropica has completed.
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CLINICAL_TRIALS research · 2011-08-16Clinical Trial Update: Frequency of Parasite Infection in Hyraxes and Sandflies During Outbreak of Leishmania Tropica Epidemic in The West Bank
The update describes the frequency of parasite infection in hyraxes and sandflies during a West Bank outbreak of Leishmania tropica.
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CLINICAL_TRIALS trial_result · 2011-08-16Clinical Trial Update: Study of the Efficacy of Daylight Activated Photodynamic Therapy in the Treatment of Cutaneous Leishmaniasis [Phase 2]
The document reports a Phase 2 study investigating the efficacy of daylight-activated photodynamic therapy for cutaneous leishmaniasis.
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CLINICAL_TRIALS trial_result · 2011-06-27Clinical Trial Update: Oral Miltefosine Plus Topical Imiquimod to Treat Cutaneous Leishmaniasis [Phase 2]
A Phase 2 clinical trial evaluating oral miltefosine in combination with topical imiquimod for cutaneous leishmaniasis has completed.
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CLINICAL_TRIALS trial_result · 2011-06-27Clinical Trial Update: Treatment of Cutaneous Leishmaniasis With a Combination of Miltefosine and Antimony [Phase 2]
A Phase 2 clinical trial evaluating the combination of miltefosine and an antimony-based therapy for cutaneous leishmaniasis was terminated.
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CLINICAL_TRIALS trial_result · 2011-03-28Clinical Trial Update: Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating wound care management strategies for patients with Old World cut…
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CLINICAL_TRIALS trial_result · 2011-01-17Clinical Trial Update: Pilot Study Using a Heat Pack to Treat Cutaneous Leishmaniasis
A pilot clinical trial is evaluating the use of a heat pack to treat cutaneous leishmaniasis.
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CLINICAL_TRIALS trial_result · 2010-11-24Clinical Trial Update: Controlled Nitric Oxide Releasing Patch Versus Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis [Phase 3]
A Phase 3 trial comparing a Controlled Nitric Oxide Releasing Patch with Meglumine Antimoniate for cutaneous leishmaniasis was terminated.
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CLINICAL_TRIALS trial_result · 2010-07-14Clinical Trial Update: Efficacy and Safety of Miltefosine or Thermotherapy for Cutaneous Leishmaniasis in Colombia. [Phase 3]
Phase 3 trial evaluating miltefosine versus thermotherapy for cutaneous leishmaniasis in Colombia has completed with results posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-06-02Clinical Trial Update: Treatment of Cutaneous Leishmaniasis With Meglumine Antimoniate Versus Meglumine Antimoniate and Allopurinol [NA]
Completed clinical trial comparing meglumine antimoniate alone versus combination therapy with allopurinol for cutaneous leishmaniasis.
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CLINICAL_TRIALS trial_result · 2010-06-02Clinical Trial Update: Miltefosine to Treat Cutaneous Leishmaniasis in Bolivia [Phase 2]
A Phase 2 trial of miltefosine to treat cutaneous leishmaniasis in Bolivia has completed.
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CLINICAL_TRIALS trial_result · 2010-04-15Clinical Trial Update: Trial of Miltefosine in Cutaneous Leishmaniasis (Brazil) [Phase 2]
This is an update on a Phase 2 trial of miltefosine for cutaneous leishmaniasis in Brazil. The study status is completed.
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CLINICAL_TRIALS trial_result · 2010-02-17Clinical Trial Update: Oral Miltefosine for the Treatment of Pediatric Cutaneous Leishmaniasis in Colombia [Phase 3]
Phase 3 clinical trial evaluating oral miltefosine for the treatment of pediatric cutaneous leishmaniasis in Colombia.
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CLINICAL_TRIALS trial_result · 2009-09-09Clinical Trial Update: Reduced Doses of Antimony Plus Ranulocyte Monocyte Colony Stimulating Factor (GM-CSF) for Cutaneous Leishmaniasis [Phase 2]
A Phase 2 trial evaluating reduced doses of an antimony-based therapy with GM-CSF for cutaneous leishmaniasis has completed.
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CLINICAL_TRIALS trial_result · 2009-01-22Clinical Trial Update: Safety and Efficacy of Low-Dose Pentavalent Antimony for Treatment of Cutaneous Leishmaniasis [Phase 4]
Phase 4 trial evaluating the safety and efficacy of low-dose pentavalent antimony for cutaneous leishmaniasis has been completed.
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CLINICAL_TRIALS trial_result · 2008-06-12Clinical Trial Update: Imiquimod Plus Antimony Immunochemotherapy for Cutaneous Leishmaniasis [Phase 3]
Phase 3 trial evaluating Imiquimod combined with antimony-based immunochemotherapy for cutaneous leishmaniasis has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Safety and Immunogenicity of a Vaccine for Cutaneous Leishmaniasis Using Recombinant Human Interleukin-12 and Aluminum Hydroxide Gel as Adjuvants [Phase 1]
Phase 1 trial evaluating safety and immunogenicity of a Cutaneous Leishmaniasis vaccine using recombinant human interleukin-12 and aluminum …
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CLINICAL_TRIALS trial_result · 2007-10-02Clinical Trial Update: Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia [Phase 2]
A Phase 2 clinical trial update evaluating a short course of miltefosine and an antimony compound for cutaneous leishmaniasis in Bolivia.
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CLINICAL_TRIALS trial_result · 2006-05-05Clinical Trial Update: Study to Evaluate the Leish-111f + MPL-SE Vaccine in Healthy Adults Not Previously Exposed to Leishmania Parasite [Phase 2]
Phase 2 clinical trial of the Leish-111f + MPL-SE vaccine in healthy adults not previously exposed to Leishmania has completed.
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CLINICAL_TRIALS trial_result · 2006-05-05Clinical Trial Update: Safety Study to Evaluate the Leish-111f + MPL-SE Vaccine in the Prevention of Cutaneous Leishmaniasis in Healthy Subjects Previously Exposed to the Leishmania Parasite [Phase 1]
This is a Phase 1 safety study evaluating the Leish-111f + MPL-SE vaccine for prevention of cutaneous leishmaniasis in healthy adults previo…