Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2008-07-08Clinical Trial Update: Efficacy Study of Targeted, Local Delivery of Drugs to Treat Crohn's Disease [Phase 1, Phase 2]
This document reports on a Phase 1/2 efficacy trial of targeted, local drug delivery for Crohn's disease. The study is sponsored by Teva GTC…
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CLINICAL_TRIALS trial_result · 2008-05-29Clinical Trial Update: Phase II Study of RR110 in Patients With Active Crohn's Disease [Phase 2]
Phase II study of RR110 in patients with active Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2008-05-14Clinical Trial Update: A Randomized Controlled Trial of VSL#3 for the Prevention of Endoscopic Recurrence Following Surgery for Crohn's Disease. [Phase 3]
This is a completed Phase 3 randomized trial evaluating VSL#3 to prevent endoscopic recurrence after Crohn's disease surgery.
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FDA approval · 2008-04-22FDA Approved: CIMZIA — Original Application (UCB, Inc.)
The FDA approved Cimzia (certolizumab pegol) in its original Biologics License Application, marking its initial approval for Crohn's disease…
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CLINICAL_TRIALS trial_result · 2008-04-09Clinical Trial Update: Phase 2 Study of the Safety and Efficacy of LDP-02 in Mildly to Moderately Active Crohn's Patients [Phase 2]
A Phase 2 clinical trial evaluating LDP-02 for safety and efficacy in patients with mild-to-moderately active Crohn's disease has completed.
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CLINICAL_TRIALS research · 2008-04-04Clinical Trial Update: An Open Label, Prospective, One Arm, Feasibility, Study for The Use of Halevy Kit for the Treatment of Perianal Fistulas in Patients With Crohn's Disease [NA]
An open-label, prospective, single-arm feasibility study assessing Halevy Kit for treating perianal fistulas in Crohn's disease; current sta…
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EMA withdrawal · 2008-03-20EMA Refused: Cimzia (certolizumab pegol) — UCB Pharma SA
EMA decision refused approval for Cimzia (certolizumab pegol) for Crohn's disease. The marketing authorization application was not granted.
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CLINICAL_TRIALS trial_result · 2008-03-07Clinical Trial Update: NI-0401 in Active Crohn's Disease [Phase 1, Phase 2]
The NI-0401 trial in active Crohn's disease has completed Phase 1 and Phase 2 studies. The sponsor is Light Chain Bioscience in collaboratio…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Monoclonal Antibody Treatment of Crohn's Disease [Phase 1]
The document reports the completion of a Phase 1 clinical trial evaluating a monoclonal antibody treatment for Crohn's disease.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Extracorporeal Photopheresis to Maintain Symptoms Remission During Steroid Withdrawal in Patients With Steroid-Dependent Crohn's Disease [Phase 1]
A Phase 1 trial evaluating extracorporeal photopheresis to sustain symptom remission during steroid withdrawal in steroid-dependent Crohn's …
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EMA withdrawal · 2008-02-14EMA Withdrawn: Trudexa (adalimumab) — Abbott Laboratories Ltd.
EMA has withdrawn Trudexa (adalimumab) from the market.
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EMA withdrawal · 2008-01-25EMA Refused: Natalizumab Elan Pharma (natalizumab) — Elan Pharma International Ltd.
The EMA refused the marketing authorization for natalizumab from Elan Pharma International Ltd. for Crohn's disease.
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CLINICAL_TRIALS trial_result · 2008-01-08Clinical Trial Update: Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease [Phase 4]
Phase 4 clinical trial assessing the diagnostic accuracy of capsule endoscopy for small bowel Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2007-12-05Clinical Trial Update: Nasal Calcitonin in the Treatment of Bone Mineral Loss in Children and Adolescents With Inflammatory Bowel Disease [NA]
The study evaluating nasal calcitonin for bone mineral loss in children and adolescents with inflammatory bowel disease has completed. The c…
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CLINICAL_TRIALS trial_result · 2007-11-29Clinical Trial Update: Treatment of the Human Anti-TNF Monoclonal Antibody Adalimumab in Moderate to Severe Crohn's Disease With Previous Exposure to Infliximab (CHOICE) [Phase 3]
A Phase 3 trial (CHOICE) assessed adalimumab in moderate-to-severe Crohn's disease patients with prior infliximab exposure; the study has co…
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CLINICAL_TRIALS trial_result · 2007-11-07Clinical Trial Update: Top Down Versus Step Up Strategies in Crohn's Disease [Phase 4]
A Phase 4 clinical trial comparing top-down (early aggressive) versus step-up (progressive) treatment strategies in Crohn's disease has comp…
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CLINICAL_TRIALS trial_result · 2007-10-22Clinical Trial Update: Atorvastatin in Moderate Active Crohns Disease [Phase 2]
Phase 2 trial evaluating atorvastatin for moderate active Crohn's disease has completed, sponsored by Skane University Hospital.
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CLINICAL_TRIALS trial_result · 2007-10-19Clinical Trial Update: An Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Crohn's Disease [Phase 2]
The document reports the results of a Phase 2 trial evaluating the efficacy and safety of Inflabloc Cap in patients with Crohn's disease.
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CLINICAL_TRIALS trial_result · 2007-09-26Clinical Trial Update: Adalimumab for the Induction and Maintenance of Clinical Remission in Subjects With Crohn's Disease [Phase 3]
Phase 3 trial update on adalimumab for induction and maintenance of clinical remission in Crohn's disease; the study status is completed.
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FDA approval · 2007-07-30FDA Approved: HUMIRA — Supplemental Application (Cordavis Limited)
The FDA approved a supplemental application for Humira (adalimumab) submitted by Cordavis Limited.
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FDA approval · 2007-06-26FDA Approved: PENTASA — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
The FDA approved a supplemental application for Pentasa (mesalamine) from Takeda Pharmaceuticals America, resulting in an approved additiona…
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CLINICAL_TRIALS research · 2007-06-19Clinical Trial Update: Crohn's Disease, Obesity and Disease Severity
This entry reports a clinical trial update involving Crohn's disease and obesity; the status is unknown.
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FDA approval · 2007-06-12FDA Approved: INFLIXIMAB — Supplemental Application (Janssen Biotech, Inc.)
FDA approved a supplemental application for infliximab (Remicade) submitted by Janssen Biotech, Inc. The approval updates the labeling to re…
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FDA approval · 2007-04-19FDA Approved: INFLIXIMAB — Supplemental Application (Janssen Biotech, Inc.)
The FDA approved a supplemental application for infliximab (Remicade) from Janssen Biotech, Inc., updating the product labeling per the supp…
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CLINICAL_TRIALS research · 2007-04-13Clinical Trial Update: Vitamin D Treatment for Crohn´s Disease [Phase 2, Phase 3]
A clinical trial update exploring Vitamin D (cholecalciferol) as a treatment for Crohn's disease in Phase 2 and Phase 3.