Crohn Disease
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Sign up freeTop drugs studied for this disease
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FDA approval · 2011-09-07FDA Approved: CIMZIA — Supplemental Application (UCB, Inc.)
FDA approved a supplemental application for Cimzia (certolizumab pegol) submitted by UCB, Inc. This action approves the changes described in…
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CLINICAL_TRIALS trial_result · 2011-09-05Clinical Trial Update: Fibrin Glue for Perianal Fistulas in Crohn's Disease: a Randomized Controlled Trial [Phase 3]
A Phase 3 randomized controlled trial evaluated fibrin glue for treating perianal fistulas in Crohn's disease; the study has completed.
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CLINICAL_TRIALS trial_result · 2011-09-02Clinical Trial Update: Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption [NA]
A completed clinical trial reports that tumor necrosis factor decreases vitamin D–dependent calcium absorption in patients with rheumatoid a…
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CLINICAL_TRIALS trial_result · 2011-08-31Clinical Trial Update: Comparison Azathioprine to Mesalazine for the Prevention of Postoperative Recurrence in the Crohn Disease [Phase 3]
A Phase 3 trial comparing azathioprine to mesalazine for preventing postoperative recurrence in Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2011-08-23Clinical Trial Update: Dose Ranging Study Comparing the Efficacy, Safety and Pharmacokinetics of Intravenous Infusions of ABT-874 vs Placebo in Subjects With Active Crohn's Disease [Phase 2]
Phase 2 dose-ranging study evaluating intravenous ABT-874 versus placebo in active Crohn's disease; the trial was terminated.
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CLINICAL_TRIALS trial_result · 2011-08-19Clinical Trial Update: Intestinal Wall Remodeling (Infliximab Therapy) in Crohn's Disease Patients Undergoing Serial Computed Tomography (CT) Enterography
This completed clinical trial evaluated intestinal wall remodeling during infliximab therapy in Crohn's disease patients undergoing serial C…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Treatment of Crohn's Fistula Using a Porcine Intestine Submucosa Graft [NA]
A trial evaluating a porcine intestine submucosa graft for Crohn's disease-related anal fistula was terminated, with results posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-08-11Clinical Trial Update: Endocytoscopy for in Vivo Determination of Mucosal Inflammatory Cells and Intestinal Disease Activity in Inflammatory Bowel Disease (IBD)
An update on a completed clinical trial evaluating endocytoscopy for in vivo determination of mucosal inflammatory cells and intestinal dise…
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CLINICAL_TRIALS trial_result · 2011-08-11Clinical Trial Update: The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of Inflammation [Phase 4]
Phase 4 clinical trial update examining whether probiotics affect recovery in inflammatory bowel disease, endothelial function, and inflamma…
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CLINICAL_TRIALS trial_result · 2011-08-11Clinical Trial Update: Endomicroscopy and Crohn´s Disease
This clinical trial update confirms the completion of a study evaluating endomicroscopy in Crohn's disease.
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Efficacy and Safety of Adalimumab in Pediatric Subjects With Moderate to Severe Crohn's Disease [Phase 3]
This clinical trial update reports efficacy and safety results from a Phase 3 study of adalimumab in pediatric patients with moderate to sev…
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CLINICAL_TRIALS trial_result · 2011-07-22Clinical Trial Update: Treatment With Infliximab in a Medical Setting (Study P05587) [Phase 4]
Phase 4 trial evaluating infliximab for Crohn's disease was terminated; results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-07-19Clinical Trial Update: Agaricus Blazei Murill (ABM) in Patients With Inflammatory Bowel Disease (IBD) [Phase 2]
A Phase 2 clinical trial evaluating Agaricus blazei Murill (ABM) in inflammatory bowel disease has completed; no efficacy or safety results …
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CLINICAL_TRIALS trial_result · 2011-07-12Clinical Trial Update: Follow-up to Welcome Study C87042 [NCT00308581] Examining Certolizumab Pegol (CDP870) in Subjects With Crohn's Disease [Phase 3]
Phase 3 follow-up study of certolizumab pegol (CDP870) in Crohn's disease completed with posted results.
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FDA approval · 2011-06-23FDA Approved: BUDESONIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for budesonide from Teva Pharmaceuticals USA, Inc.
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CLINICAL_TRIALS trial_result · 2011-06-23Clinical Trial Update: Microparticles in Pediatric Inflammatory Disease
A clinical trial sponsored by Indiana University evaluating microparticles in pediatric inflammatory disease (Crohn's disease and ulcerative…
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CLINICAL_TRIALS research · 2011-06-14Clinical Trial Update: Probiotics in GastroIntestinal Disorders [Phase 2, Phase 3]
Clinical trial update describing Phase 2 and Phase 3 studies evaluating probiotics for ulcerative colitis and Crohn's disease.
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CLINICAL_TRIALS trial_result · 2011-06-08Clinical Trial Update: Safety and Immunogenicity of a TNFa Kinoid in Patients With Crohn's Disease [Phase 1, Phase 2]
This report covers the safety and immunogenicity results from a Phase 1/2 trial of a TNF-α kinoid vaccine in patients with Crohn's disease.
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CLINICAL_TRIALS research · 2011-06-01Clinical Trial Update: Retrospective Data Analysis in Crohn's Disease
This update covers a retrospective data analysis in Crohn's disease sponsored by Ferring Pharmaceuticals; the study status is completed.
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CLINICAL_TRIALS research · 2011-05-30Clinical Trial Update: Impact of Anti-Tumor Necrosis Factor (TNF) Antibodies on the T-lymphocyte and Macrophage Cooperation in Crohn Disease [NA]
A clinical trial update examines whether anti-TNF antibodies alter T-lymphocyte and macrophage interactions in Crohn's disease. The study wa…
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FDA approval · 2011-05-27FDA Approved: MERCAPTOPURINE — Supplemental Application (Florida Pharmaceutical Products, LLC)
The FDA has approved a supplemental application for mercaptopurine from Florida Pharmaceutical Products, LLC.
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CLINICAL_TRIALS trial_result · 2011-05-25Clinical Trial Update: Examining the Long Term Safety, Efficacy, and Corticosteroid-sparing Effect of Certolizumab Pegol in Crohn's Disease [Phase 3]
A Phase 3 trial update evaluating long-term safety, efficacy, and corticosteroid-sparing effects of certolizumab pegol in Crohn's disease.
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CLINICAL_TRIALS trial_result · 2011-05-19Clinical Trial Update: A Study Comparing the Acceptability of Pentasa® Sachets Versus Pentasa® Tablets in Children With Crohn´s Disease [Phase 4]
This clinical trial update compares the acceptability of Pentasa sachets versus Pentasa tablets in children with Crohn's disease (Phase 4, c…
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: A Study of the Safety and Efficacy of Infliximab (Remicade) in Pediatric Patients With Crohn's Disease [Phase 3]
A Phase 3 pediatric trial evaluating infliximab (Remicade) for Crohn's disease has completed, assessing its safety and efficacy.
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CLINICAL_TRIALS trial_result · 2011-04-29Clinical Trial Update: Assessment of the Social Cost of Crohn's Disease: Economic and Quality of Life Aspects (Study P04560)
A completed clinical trial (P04560) sponsored by Merck evaluated the economic impact and quality of life for Crohn's disease, an inflammator…