Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: Understanding and Treating Neuropsychiatric Symptoms of Pediatric Physical Illness [NA]
A completed clinical study examining neuropsychiatric symptoms in pediatric inflammatory bowel disease and related depression.
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FDA approval · 2014-05-20FDA Approved: ENTYVIO — Original Application (Takeda Pharmaceuticals America, Inc.)
FDA approved Entyvio (vedolizumab) in its original application for treatment of moderate-to-severe Crohn's disease and ulcerative colitis.
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Oral Budesonide vs. Oral Mesalazine in Active Crohn's Disease (CD) [Phase 3]
Phase 3 trial comparing oral budesonide with oral mesalazine in active Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2014-05-16Clinical Trial Update: Anti TNF α Improves Endothelial Dysfunction in IBD Patients
A clinical trial update indicates that anti-TNF alpha therapy improves endothelial dysfunction in patients with Crohn's disease.
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CLINICAL_TRIALS trial_result · 2014-04-29Clinical Trial Update: Capsule Endoscopy Crohn's Disease Activity Index - Validation Multi Center Study [Phase 3]
A multicenter Phase 3 trial validating the Capsule Endoscopy Crohn's Disease Activity Index has completed.
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Assessment of Small Bowel Healing in Crohn's Disease Patients Treated With Cimzia Using Wireless Capsule Endoscopy [NA]
This clinical trial update reports on the assessment of small bowel healing in Crohn's disease patients treated with Cimzia (certolizumab pe…
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CLINICAL_TRIALS research · 2014-04-10Clinical Trial Update: An Observational Study of Lymphoma in Patients With Rheumatoid Arthritis or Crohn's Disease.
An observational study examining lymphoma in patients with rheumatoid arthritis or Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Understanding the Relationship Between Infliximab Levels to Clinical Response of Remicade in Crohn's Disease [NA]
This terminated clinical trial evaluated the relationship between infliximab trough levels and clinical response to Remicade in Crohn's dise…
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CLINICAL_TRIALS research · 2014-03-28Clinical Trial Update: Cost-effectiveness of TPMT Pharmacogenetics [NA]
A completed study evaluating the cost-effectiveness of TPMT pharmacogenetic testing in inflammatory bowel diseases, including Crohn's diseas…
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CLINICAL_TRIALS trial_result · 2014-03-27Clinical Trial Update: Crohn's Disease Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial evaluating stem cell transplantation for Crohn's disease conducted by Northwestern University has been terminated; …
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EMA approval · 2014-03-21European Medicines Agency recommends approval of a locally targeted treatment for ulcerative colitis and Crohn's disease
The European Medicines Agency recommends approval of a locally targeted treatment for ulcerative colitis and Crohn's disease.
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CLINICAL_TRIALS trial_result · 2014-03-21Clinical Trial Update: Impact of Disease Activity and Nutrition Treat on Postoperative Recurrence and Complications After Bowel Resection for Crohn's Disease [NA]
A completed clinical trial from Jinling Hospital evaluating how disease activity and nutrition treatment influence postoperative recurrence …
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CLINICAL_TRIALS trial_result · 2014-03-20Clinical Trial Update: Trial of a Treatment Algorithm for the Management of Crohn's Disease [Phase 4]
This Phase 4 clinical trial evaluates a treatment algorithm for managing Crohn's disease. The study status is reported as completed.
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CLINICAL_TRIALS trial_result · 2014-03-18Clinical Trial Update: Special Investigation in Patients With Crohn's Disease (All Patients Investigation)
This document reports the completion of a special investigation trial in Crohn's disease and notes that results have been posted.
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CLINICAL_TRIALS trial_result · 2014-03-18Clinical Trial Update: A Long-term Safety Study of Infliximab (Remicade)
The document reports the completion of a long-term safety study of infliximab (Remicade) across rheumatoid arthritis, Crohn's disease, and p…
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CLINICAL_TRIALS research · 2014-03-17Clinical Trial Update: a Single-center Registered Clinical Research of Chinese Patients With Moderate to Severe Crohn's Disease
A registered single-center clinical study in Chinese patients with moderate to severe Crohn's disease. The document notes an unknown study s…
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CLINICAL_TRIALS trial_result · 2014-03-12Clinical Trial Update: Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease
A completed clinical trial investigating the significance of Ficolin 2 in determining serological activity in Crohn's disease.
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CLINICAL_TRIALS trial_result · 2014-03-10Clinical Trial Update: Effect of VSL#3 on Intestinal Permeability in Pediatric Crohn's Disease [Phase 3]
Phase 3 trial evaluating the effect of VSL#3 on intestinal permeability in pediatric Crohn's disease has completed.
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FDA approval · 2014-03-04FDA Approved: USTEKINUMAB — Supplemental Application (Janssen Biotech, Inc.)
FDA approved a supplemental application for ustekinumab from Janssen Biotech, Inc., leading to changes in its labeling/approved use.
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Imuran (Azathioprine) Dose-Ranging Study in Crohn's Disease [Phase 3]
A Phase 3 dose-ranging study of azathioprine (Imuran) in Crohn's disease was terminated.
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CLINICAL_TRIALS trial_result · 2014-02-14Clinical Trial Update: Exacerbating Factors in Inflammatory Bowel Disease
The document provides an update on a completed clinical trial examining factors that exacerbate inflammatory bowel disease, including ulcera…
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CLINICAL_TRIALS trial_result · 2014-02-06Clinical Trial Update: Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult [Phase 4]
This Phase 4 clinical trial update investigates how enteral nutrition in combination with corticosteroids affects the intestinal flora durin…
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CLINICAL_TRIALS trial_result · 2014-02-06Clinical Trial Update: Hematopoietic Stem Cell Support in Patients With Severe Crohn's Disease [Phase 1]
This Phase 1 study evaluating hematopoietic stem cell support in patients with severe Crohn's disease was terminated.
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CLINICAL_TRIALS research · 2014-02-05Clinical Trial Update: Metabolomic Analysis, a Potential Tool to Direct Treatment With Adalimumab in Crohn's Disease (CD)
A completed clinical trial evaluated whether metabolomic analysis could guide adalimumab therapy in Crohn's disease.
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Cognition and Emotion in the SII and IBD [NA]
A completed clinical trial investigating cognition and emotion in irritable bowel syndrome and inflammatory bowel disease (including Crohn's…