Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-20Clinical Trial Update: Thalidomide Results in Diminished Ovarian Reserve in Reproductive Age Female IBD Patients [NA]
A clinical trial update reports that thalidomide exposure in reproductive-age females with Crohn's disease may be associated with diminished…
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CLINICAL_TRIALS trial_result · 2016-12-14Clinical Trial Update: Fecal Microbiota Transplantation (FMT) in the Management of Active Crohn's Disease [Phase 1, Phase 2]
Clinical trial update reports on fecal microbiota transplantation for active Crohn's disease in Phase 1 and Phase 2, with the trial status s…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease Who Have Failed or Are Intolerant to Tumor Necrosis Factor (TNF) Antagonist Therapy (UNITI-1) [Phase 3]
A Phase 3 study (UNITI-1) evaluated ustekinumab in Crohn's disease patients who failed or were intolerant to TNF antagonists. The trial resu…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Effect of the Consumption of a Probiotic Strain on the Prevention of Post-operative Recurrence in Crohn's Disease [NA]
This document reports the completion of a clinical trial evaluating whether consuming a probiotic strain can reduce postoperative recurrence…
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CLINICAL_TRIALS research · 2016-12-06Clinical Trial Update: Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease
A completed clinical trial from Oslo University Hospital investigated trough levels of anti-TNF-alpha therapies in inflammatory bowel diseas…
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: A Study to Evaluate CC-5013 in the Treatment of Adolescents and Adults With Moderately Severe Crohn's Disease [Phase 2]
The Phase 2 study evaluating CC-5013 in adolescents and adults with moderately severe Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Eicosapentaenoic Free Fatty Acid and Fecal Calprotectin in Inflammatory Bowel Diseases [NA]
This clinical trial update notes that the study evaluating eicosapentaenoic free fatty acid and fecal calprotectin in inflammatory bowel dis…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Follow-up Study of Autologous Cultured Adipose-derived Stem Cells for the Crohn's Fistula
This is a follow-up study using autologous cultured adipose-derived stem cells to treat Crohn's fistula. The trial status is completed.
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CLINICAL_TRIALS trial_result · 2016-11-21Clinical Trial Update: Immune Modulation From Trichuris Trichiura
A completed clinical trial investigating immune modulation by exposure to Trichuris trichiura in Crohn's disease, ulcerative colitis, and in…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Treatment of Fistulous Crohn's Disease by Implant of Autologous Mesenchymal Stem Cells Derived From Adipose Tissue [Phase 1, Phase 2]
This entry reports on a completed Phase 1/2 clinical trial evaluating autologous adipose tissue-derived mesenchymal stem cells for treating …
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Induced Adult Refractory Active Crohn's Disease Clinical Relieving by Using Thalidomide [EARLY_Phase 1]
Early-stage Phase 1 clinical trial update evaluating thalidomide for adults with refractory active Crohn's disease; current status is not di…
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: Phase III Study of D9421-C 9 mg in Patients With Active Crohn's Disease in Japan [Phase 3]
Phase III study of D9421-C 9 mg for active Crohn's disease in Japan completed; results posted on 2016-10-31.
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CLINICAL_TRIALS research · 2016-10-26Clinical Trial Update: Clinical Course of Korean Crohn's Disease Cohort
Clinical trial update describing the clinical course of Crohn's disease within a Korean cohort.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: T and B Cell Responses in Autoimmune Diseases
A clinical trial evaluating T and B cell responses in autoimmune diseases has been terminated. The update notes the study status and partici…
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CLINICAL_TRIALS research · 2016-10-24Clinical Trial Update: RED-FLAGS Index Validation in Crohn's Disease Patients
This entry provides an update on the RED-FLAGS Index validation study in Crohn's disease patients, sponsored by Istituto Clinico Humanitas. …
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Crohn's Disease [Phase 2]
Phase 2 trial update reporting safety and efficacy of Extracorporeal Photoimmune Therapy with UVADEX for Crohn's disease.
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: A Phase I Study Evaluating Autologous Bone Marrow Derived Mesenchymal Stromal for Crohn's Disease. [Phase 1]
Phase I study evaluating autologous bone marrow-derived mesenchymal stromal cells for Crohn's disease has completed. The trial is sponsored …
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CLINICAL_TRIALS trial_result · 2016-10-14Clinical Trial Update: Safety and Efficacy of MT-1303 in Subjects With Moderate to Severe Active Crohn's Disease [Phase 2]
A Phase 2 study of MT-1303 in moderate to severe Crohn's disease has completed. The trial reported safety and efficacy findings.
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Biomarkers of Intestinal Mucosal Healing in Crohn's Disease (P08143)
Clinical trial update reporting biomarkers of intestinal mucosal healing in Crohn's disease; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: Infliximab for the Prevention of Recurrent Crohn's Disease After Surgery [Phase 4]
Phase 4 trial evaluating infliximab for prevention of recurrent Crohn's disease after surgical resection; the study is completed and results…
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CLINICAL_TRIALS withdrawal · 2016-09-23Clinical Trial Update: Vedolizumab Subcutaneous (SC) Versus Intravenous (IV) in Ulcerative Colitis or Crohn's Disease [Phase 2]
Phase 2 trial comparing subcutaneous versus intravenous vedolizumab in ulcerative colitis and Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-09-16Clinical Trial Update: Effectiveness and Safety of Spondylitis Related to Inflammatory Bowel Disease [Phase 4]
Phase 4 trial evaluating the effectiveness and safety of treatments for spondyloarthritis related to inflammatory bowel disease has been wit…
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CLINICAL_TRIALS trial_result · 2016-09-05Clinical Trial Update: Efficacy of Acupuncture and Moxibustion Treatment in Patients With Quiescent Crohn's Disease:Evaluation With fMRI [NA]
A completed clinical trial evaluating the efficacy of acupuncture and moxibustion for quiescent Crohn's disease, assessed with functional MR…
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CLINICAL_TRIALS trial_result · 2016-09-02Clinical Trial Update: Efficacy of Exclusive Enteral Nutrition in Adult Active Crohn's Disease
A completed clinical trial assessing the efficacy of exclusive enteral nutrition in adults with active Crohn's disease, including patients w…
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CLINICAL_TRIALS research · 2016-08-25Clinical Trial Update: Genomic/Epigenomic Biomarkers of Deregulation of Immune System in Inflammatory Bowel Diseases
The update describes a study examining genomic and epigenomic biomarkers of immune system deregulation in Crohn's disease; the current statu…