Crohn Disease
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Sign up freeTop drugs studied for this disease
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FDA approval · 2017-06-05FDA Approved: MESALAMINE — Original Application (Zydus Lifesciences Limited)
FDA approved the original application for mesalamine from Zydus Lifesciences Limited, confirming the generic product for inflammatory bowel …
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Monitoring Disease Activity Using Video Capsule Endoscopy (VCE) in Crohn's Disease (CD) Subjects [NA]
Completed clinical trial evaluating disease activity monitoring in Crohn's disease using Video Capsule Endoscopy (VCE); results were posted …
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CLINICAL_TRIALS withdrawal · 2017-05-24Clinical Trial Update: Calprotectin-Directed Humira® Maintenance Therapy (CADHUM) [Phase 3]
A Phase 3 trial evaluating calprotectin-directed maintenance therapy with Humira (adalimumab) for Crohn's disease has been withdrawn.
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: Surgically Resected Crohn's Disease Patients: Prognostic Factors for Re-operation and New Score Building
A clinical trial update focusing on prognostic factors for re-operation after surgical resection in Crohn's disease. It also describes the d…
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Comparison of Capso Vision SV-1 to PillCam SB2 in the Evaluation of Subjects With Suspected Small Bowel Disease [NA]
A completed clinical trial compared Capso Vision SV-1 to PillCam SB2 for evaluation of suspected small bowel disease, with results posted in…
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CLINICAL_TRIALS research · 2017-05-09Clinical Trial Update: Resting Energy Expenditure Evaluation in Subjects With Crohn's Disease
A clinical trial update evaluating resting energy expenditure in subjects with Crohn's disease.
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD
This clinical trial update reports a head-to-head comparison of two fecal biomarkers to screen children for inflammatory bowel disease, with…
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CLINICAL_TRIALS research · 2017-05-02Clinical Trial Update: Urinary Prostaglandin E Metabolite (PGE-M), A Metabolite of Prostaglandin E2 (PGE2): A Novel Biomarker of Crohn's Disease Activity [NA]
The update discusses urinary PGE-M as a novel biomarker for Crohn's disease activity, based on a completed trial.
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CLINICAL_TRIALS trial_result · 2017-05-01Clinical Trial Update: The ImageKids Study: Developing the pMEDIC and the PICMI [NA]
The ImageKids Study evaluating pMEDIC and the PICMI for Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's Disease [Phase 2]
Pfizer completed a Phase 2 study evaluating the safety and efficacy of CP-690,550 (tofacitinib) as induction therapy in moderate to severe C…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Transplantation of Bone Marrow Mesenchymal Stem Cell in Crohn's Disease [Phase 1]
A Phase 1 clinical trial evaluating transplantation of bone marrow-derived mesenchymal stem cells for Crohn's disease; the current status of…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Evaluate PF-00547659 On Cerebrospinal Fluid Lymphocytes In Volunteers With Crohn's Disease Or Ulcerative Colitis Who Failed Or Did Not Tolerate Anti-TNFs [Phase 1]
Phase 1 trial evaluating PF-00547659 levels in cerebrospinal fluid lymphocytes in volunteers with Crohn's disease or ulcerative colitis who …
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients
A clinical trial update describing how the host immune system responds to Clostridioides difficile infection in patients with inflammatory b…
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Prevalence and Clinical Course of Chronic Hep B Infection in IBD and Rheumatologic Disease [NA]
A terminated observational trial assessed the prevalence and clinical course of chronic hepatitis B infection in patients with inflammatory …
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Study Evaluating Ovasave, an Autologous Cell Therapy, in Patients With Active Crohn's Disease [Phase 2]
A Phase 2 study evaluating Ovasave, an autologous cell therapy, for active Crohn's disease has been terminated.
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FDA approval · 2017-04-21FDA Approved: RENFLEXIS — Original Application (Organon LLC)
The FDA approved RENFLEXIS (infliximab) from Organon LLC based on an original application, making it a biosimilar to Remicade. The approval …
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Endoscopic Ultrasound (EUS) Guided Treatment With Humira for Crohn's Perianal Fistulas [Phase 4]
Phase 4 trial assessing endoscopic ultrasound-guided treatment with Humira (adalimumab) for Crohn's disease-related perianal fistulas; resul…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Study To Test Whether PF-00547659 Is Safe And Improves Disease Symptoms In Patients With Crohn's Disease [Phase 2]
Phase 2 clinical trial evaluating PF-00547659 for safety and symptom improvement in Crohn's disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Effectiveness and Safety in Patients With Crohn´s Disease in Clinical Routine
This update reports results from a completed AbbVie-sponsored trial assessing the effectiveness and safety of Crohn's disease treatment in r…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Study to Look at Benefit of Surgical Drainage Before Beginning Medical Therapy for Crohns Perianal Fistulas [NA]
The trial assessing whether surgical drainage before initiating medical therapy for Crohn's disease-related perianal fistulas has completed.
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CLINICAL_TRIALS other · 2017-04-04Clinical Trial Update: Transition of Inflammatory Bowel Disease (IBD) Patients From Pediatric to Adult Gastroenterologist (GI) [NA]
A Vanderbilt-sponsored clinical trial evaluating the transition of pediatric inflammatory bowel disease patients to adult gastroenterology w…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy and Safety of NNC0114-0006 in Subjects With Active Crohn's Disease [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of NNC0114-0006 in active Crohn's disease ha…
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: Efficacy of Infliximab in the Treatment of Patients Affected by Corticodependent Crohn's Disease (P02732) [Phase 3]
A Phase 3 trial evaluating infliximab for cortico-dependent Crohn's disease has been terminated.
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: B0151005 Open-Label Extension Study [Phase 2]
Open-label extension study (Phase 2) for Crohn's disease completed; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Protein and Energy Metabolism in Pediatric Crohn's Disease [Phase 1]
Phase 1 trial evaluating protein and energy metabolism in pediatric Crohn's disease has completed.