Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-03-06Clinical Trial Update: Evaluation of Efficacy and Safety of MEDI2070 in Patients With Active, Moderate-to-severe Crohn's Disease. [Phase 2]
Phase 2 trial update evaluating the efficacy and safety of MEDI2070 in active moderate-to-severe Crohn's disease (results posted).
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EMA withdrawal · 2019-03-05EMA Withdrawn: Solymbic (adalimumab) — Amgen Europe B.V.
Solymbic (adalimumab) has been withdrawn from the market by Amgen Europe B.V.
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FDA approval · 2019-02-21FDA Approved: PREDNISONE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for prednisone from Mylan Pharmaceuticals, indicating approval of an existing generic product's …
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CLINICAL_TRIALS research · 2019-02-18Clinical Trial Update: A Trial for Prevention of Loss of the Effect of Biological Drugs in Patients With Inflammatory Bowel Disease [NA]
Clinical trial update on preventing loss of response to biological drugs in inflammatory bowel disease; no results or status details are pro…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Web-based Monitoring in Children and Adolescents With Inflammatory Bowel Disease [NA]
Clinical trial update for a web-based monitoring intervention in children and adolescents with inflammatory bowel disease; status completed …
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CLINICAL_TRIALS research · 2019-02-15Clinical Trial Update: Unraveling a Potential Connection Between Bilirubin Metabolism, Gut Microbiota and Inflammatory Bowel Diseases
This clinical trial update explores a potential link between bilirubin metabolism, gut microbiota, and inflammatory bowel diseases, includin…
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CLINICAL_TRIALS research · 2019-02-15Clinical Trial Update: Evaluation of the Clinical and Immunological Impact of Two Therapeutic Strategies in Chronic Inflammatory Diseases [NA]
A terminated clinical trial update from University Hospital Lille evaluating two therapeutic strategies for inflammatory bowel diseases; no …
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CLINICAL_TRIALS trial_result · 2019-02-07Clinical Trial Update: Evaluating a Shared Decision Making Program for Crohn's Disease [NA]
This completed clinical trial evaluated a shared decision making program for patients with Crohn's disease.
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CLINICAL_TRIALS research · 2019-02-07Clinical Trial Update: Fecal Calprotectin Collection Protocol
This clinical trial update outlines the fecal calprotectin collection protocol used in a completed trial sponsored by DiaSorin.
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Proteomic Analysis of Crohn's Disease Macrophages in Response or Not to AIEC
The completed trial analyzed the proteomic profile of macrophages from Crohn's disease patients to assess their response to AIEC bacteria, w…
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CLINICAL_TRIALS research · 2019-01-31Clinical Trial Update: Multimodal Approach in IBD Patients
This clinical trial update describes a multimodal approach in inflammatory bowel disease patients, including ulcerative colitis and Crohn's …
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: A Long-term Active Treatment Study of Mongersen (GED-0301) in Subjects With Crohn's Disease [Phase 3]
A Phase 3 long-term active treatment study of Mongersen (GED-0301) for Crohn's disease was terminated, and results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice
This clinical trial update reports on patient adherence attitudes toward scheduled adalimumab maintenance therapy across multiple inflammato…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Efficacy and Safety Study of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn's Disease [Phase 3]
Phase 3 trial of Mongersen (GED-0301) for active Crohn's disease was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-01-17Clinical Trial Update: An Innovative Treatment for Fistula-in-ano in Crohn Disease : Local Micro Reinjection of Autologous Fat and SVF [Phase 1, Phase 2]
This clinical trial update reports Phase 1/2 results for a treatment using local microinjection of autologous fat and stromal vascular fract…
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CLINICAL_TRIALS research · 2019-01-16Clinical Trial Update: Fecal Microbiota Transplantation and Analysis of Fecal Microbiome in IBD Patients [NA]
This clinical trial update from Yonsei University concerns fecal microbiota transplantation and analysis of the fecal microbiome in patients…
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CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Adalimumab in Chinese Subjects With Moderate to Severe Crohn's Disease [Phase 3]
A Phase 3 study evaluating safety and efficacy of adalimumab in Chinese patients with moderate to severe Crohn's disease has completed with …
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CLINICAL_TRIALS trial_result · 2018-12-28Clinical Trial Update: Curcumin Associated With Thiopurin in the Prevention of Post-op Recurrence in Crohn Disease [Phase 3]
A Phase 3 trial investigated curcumin associated with thiopurine for preventing postoperative recurrence in Crohn's disease; study status sh…
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Post-Marketing Surveillance of Humira in Korean Pediatric Crohn's Disease (CD) Patients Under the "New-Drug Re-examination"
Post-marketing surveillance study of Humira in Korean pediatric Crohn's disease patients completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-12-13Clinical Trial Update: Adalimumab Intralesional in Intestinal Strictures of Crohn's Disease Patients [Phase 3]
A Phase 3 trial evaluating adalimumab intralesional injections for intestinal strictures in Crohn's disease was terminated.
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Efficacy, Safety and Pharmacokinetics of BI 655066/ABBV-066 (Risankizumab) in Patients With Active, Moderate-to-severe Crohn's Disease. [Phase 2]
Phase 2 trial update on risankizumab (BI 655066/ABBV-066) for active moderate-to-severe Crohn's disease evaluating efficacy, safety, and pha…
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CLINICAL_TRIALS trial_result · 2018-11-14Clinical Trial Update: Open Label Study to Evaluate Long Term Efficacy, Safety and Tolerability of Repeated Dosing in Subjects With Crohn's Disease and Who Participated and Successfully Completed M14-115 [Phase 3]
Open-label long-term extension study assessing repeated dosing in Crohn's disease patients who completed a prior Phase 3 trial; results post…
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FDA approval · 2018-10-30FDA Approved: ADALIMUMAB — Original Application (Sandoz Inc)
FDA approved the original application for the adalimumab biosimilar ADALIMUMAB-ADAZ from Sandoz Inc. The approval covers the same indication…
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CLINICAL_TRIALS trial_result · 2018-10-18Clinical Trial Update: Salvage Therapy With High/Low Methotrexate for Loss of Response to Infliximab Dose Escalation [Phase 4]
Phase 4 clinical trial evaluating salvage therapy with high/low methotrexate for loss of response to infliximab dose escalation in Crohn's d…
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FDA approval · 2018-10-16FDA Approved: HUMIRA — Supplemental Application (Cordavis Limited)
FDA approved a supplemental application for Humira (adalimumab) submitted by Cordavis Limited.