Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2026-04-16Clinical Trial Update: Fecal Microbiome Signature of Multi-Strain Probiotics Supplementation in Children and Adolescents With Inflammatory Bowel Disease [NA]
Clinical trial evaluating multi-strain probiotics for children and adolescents with inflammatory bowel disease. The study status is NOT_YET_…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Mesenchymal Stem Cells for the Treatment of Rectovaginal Fistulas in Participants With Crohn's Disease [Phase 1, Phase 2]
A Phase 1/2 trial evaluating mesenchymal stem cells for rectovaginal fistulas in Crohn's disease has been terminated.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Mesenchymal Stem Cells for the Treatment of Perianal Fistulizing Crohn's Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating mesenchymal stem cells for perianal fistulizing Crohn's disease has been terminated.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES) [NA]
A clinical trial evaluating mesenteric-sparing versus high ligation ileocolic resection for preventing Crohn's disease recurrence has been t…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Study of Ossium Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in the Setting of Crohn's Disease [Phase 1, Phase 2]
Clinical trial update indicates that the Ossium Mesenchymal Stem Cells study for pouch fistulas in Crohn's disease (Phase 1/Phase 2) has bee…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis [NA]
A clinical trial is examining ketogenic and carnivore diets for inflammatory bowel disease and rheumatoid arthritis, and the study is curren…
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FDA approval · 2026-04-15FDA Approved: USTEKINUMAB — Supplemental Application (Janssen Biotech, Inc.)
FDA approved a supplemental application for ustekinumab submitted by Janssen Biotech, Inc. The action pertains to a supplemental submission …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Immunological Characteristics of Preclinical IBD
This clinical trial update describes a preclinical study examining the immunological characteristics of inflammatory bowel disease, includin…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease [Phase 3]
A Phase 3 pediatric trial is evaluating the efficacy, safety, and pharmacokinetics of Upadacitinib in moderately to severely active Crohn's …
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CLINICAL_TRIALS withdrawal · 2026-04-15Clinical Trial Update: Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's [Phase 1]
The ClinicalTrials.gov entry shows a Phase 1 trial investigating mesenchymal stem cells for pouch fistulas in Crohn's disease has been withd…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Assess Real-world Outcomes for Long-Term Use of Guselkumab
This entry describes a real-world outcomes study evaluating long-term guselkumab use in inflammatory bowel diseases, focusing on ulcerative …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Fecal Microbiome Transplant [Phase 1]
This is a Phase 1 clinical trial update on fecal microbiome transplantation that is currently enrolling by invitation for patients with Clos…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation Combined With Anti-inflammatory Diet in Crohn's Disease [NA]
This is a clinical trial investigating the combination of repetitive transcranial magnetic stimulation (rTMS) with an anti-inflammatory diet…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Positron Emission Tomography Study of Changes in [11C]AZ14132516 Uptake Following Administration of AZD7798 to Patients With Crohn's Disease. [Phase 1]
Phase 1 PET imaging study update examining changes in uptake of the radiotracer [11C]AZ14132516 after administering AZD7798 in patients with…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: An Observational, Multicenter Study to Evaluate the Effectiveness of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
An observational multicenter study to evaluate the effectiveness of guselkumab for Crohn's disease after surgical resection; the study statu…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Digestive Evolution of Children With Crohn's Disease or Ulcerative Colitis Whose Anti-TNFα Treatment Was Switched to Ustekinumab Due to Paradoxical Psoriasis,
A pediatric clinical trial evaluating outcomes for children with Crohn's disease or ulcerative colitis after switching from anti-TNF therapy…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Loss of RESponse to Ustekinumab Treated by Dose Escalation [Phase 3]
Phase 3 clinical trial update on patients with Crohn's disease showing loss of response to ustekinumab was addressed by dose escalation; res…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD) [Phase 3]
Phase 3 study comparing IV/SC risankizumab to IV/SC ustekinumab to evaluate changes in CDAI in adults with moderate-to-severe Crohn's diseas…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease [Phase 3]
Phase 3 pediatric trial evaluating guselkumab for moderately to severely active Crohn's disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Long-term Extension Study of Ustekinumab in Pediatric Participants [Phase 3]
Long-term extension Phase 3 trial of ustekinumab in pediatric patients is being conducted for Crohn's disease and ulcerative colitis, with a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
A clinical trial is assessing the long-term safety of ustekinumab compared with other biologics in patients with Crohn's disease and ulcerat…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Biologics and Paediatric Enteral Nutrition in Crohn's Disease Study [NA]
The University of Glasgow is conducting a trial in pediatric Crohn's disease to evaluate biologics and paediatric enteral nutrition, current…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Database Study of Disease, Treatment Patterns and Healthcare Use in Children With Inflammatory Bowel Diseases in Korea
This document reports on an observational database study in Korea examining disease patterns, treatment approaches, and healthcare utilizati…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants [Phase 3]
A long-term extension study of guselkumab in pediatric participants with Crohn's disease, ulcerative colitis, psoriatic arthritis, and juven…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease [Phase 3]
A Roche-sponsored Phase 3 trial update announcing induction therapy with Afimkibart (RO7790121) for moderately to severely active Crohn's di…