Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Abdominally Targeted Management Exercises for Crohn's Disease Patients (TAME-CD) [NA]
A clinical trial named TAME-CD is evaluating abdominally targeted management exercises for Crohn's disease and inflammatory bowel disease, c…
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FDA approval · 2025-04-07FDA Approved: ADALIMUMAB — Supplemental Application (CELLTRION USA, Inc.)
FDA approved a supplemental application for ADALIMUMAB-AATY, a biosimilar adalimumab from Celltrion USA, Inc., in connection with its regula…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Ustekinumab With Semi-EN vs Exclusive EN for Preoperative Crohn's Disease Optimization. [NA]
A clinical trial comparing ustekinumab with semi-elemental enteral nutrition versus exclusive enteral nutrition for preoperative optimizatio…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Crohn Disease [NA]
A clinical trial update describes a study evaluating fecal transplant and dietary changes in newly diagnosed active Crohn's disease. The stu…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Pre-treatment With Azithromycin to Reduce Immunogenicity to to Anti-TNF Agents in Patients With Crohn's Disease [Phase 2]
Phase 2 clinical trial evaluating pre-treatment with azithromycin to reduce immunogenicity to anti-TNF therapy in Crohn's disease, currently…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies [NA]
This clinical trial evaluates the effect of fecal microbiota transplant and dietary changes on Crohn's disease activity in patients receivin…
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: A Study of Long-term Effects of Vedolizumab Subcutaneous in Adults With Ulcerative Colitis and Crohn's Disease [Phase 3]
Phase 3 trial evaluating long-term safety of Vedolizumab given subcutaneously in adults with Ulcerative Colitis and Crohn's Disease; study c…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Immunogenicity of Herpes Zoster Subunit Vaccine in Inflammatory Bowel Disease Patients Treated With Vedolizumab [Phase 4]
A Phase 4 study assessing the immunogenicity of a herpes zoster subunit vaccine in inflammatory bowel disease patients treated with vedolizu…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: A Study of E6011 in Participants With Active Crohn's Disease [Phase 2]
Completed Phase 2 trial of E6011 in active Crohn's disease; results have been posted.
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FDA approval · 2025-04-01FDA Approved: USTEKINUMAB — Supplemental Application (Janssen Biotech, Inc.)
FDA approved a supplemental application for ustekinumab (Stelara) by Janssen Biotech, Inc.
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: A Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating human TH-SC01 cell injections for perianal fistulas in Crohn's disease patients.
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Efficacy and Safety of Upatinib in the Treatment of Active Anal Fistulas in Crohn's Disease [Phase 1]
A Phase 1 clinical trial update evaluating the safety and preliminary efficacy of Upatinib for active anal fistulas in Crohn's disease, with…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Health Benefits of Tart Cherry in Crohn's Disease [NA]
This clinical trial update reports on a study evaluating tart cherry for Crohn's disease, which is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Proof of Concept Human Study: Dietary Intervention to Modify Intestinal Inflammation in IBD [NA]
A proof-of-concept human trial evaluating a dietary intervention to reduce intestinal inflammatory activity in inflammatory bowel disease is…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Long-term Study of Semapimod (CNI-1493) for Treatment of Crohn's Disease [Phase 2]
This update reports the completion of a long-term Phase 2 clinical trial evaluating Semapimod (CNI-1493) for Crohn's disease. The trial was …
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: A Study to Evaluate Non-invasive Measurements of the Inflammatory Status in Patients with IBD [NA]
A clinical trial is evaluating non-invasive measurements of inflammatory status in patients with inflammatory bowel disease, including ulcer…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: The Bacterial Secretome in IBD
This clinical trial update notes that a study on the bacterial secretome in inflammatory bowel diseases has completed. The sponsor is the Me…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Microbial Community Characteristics in Intestinal Mucosal Tissue of Patients With CD
Clinical trial update from Shandong University studying microbial community characteristics in intestinal mucosal tissue of patients with Cr…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Genome Analysis Across Populations in Inflammatory Bowel Disease
A clinical trial is recruiting to study genome analysis across populations in inflammatory bowel disease, including ulcerative colitis and C…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Infliximab Biosimilar "Pfizer" Drug Use Investigation (Crohn's Disease or Ulcerative Colitis)
Results have been posted for Pfizer's infliximab biosimilar trial evaluating its use in Crohn's disease and ulcerative colitis.
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Changing the Future of Intestinal Failure in Intestinal Chronic Inflammation (INT-FAIL) [NA]
A clinical trial update for the INT-FAIL study shows the trial is active but not currently recruiting. The conditions include intestinal fai…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Clinical Trial to Evaluate if the Laparoscopic Administration of Cells Derived From the Fatty Tissue Can Improve the Inflammatory Stenosis in Patient With Crohn's Disease [Phase 1, Phase 2]
A Phase 1/Phase 2 trial evaluating laparoscopic administration of adipose tissue–derived cells for inflammatory stenosis in Crohn disease ha…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Feasibility of a Minimally Invasive Diagnostic Algorithm in Suspected Crohn's Disease [NA]
This trial update describes a study evaluating a minimally invasive diagnostic algorithm for suspected Crohn's disease. The study is current…
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FDA approval · 2025-03-18FDA Approved: TYSABRI — Supplemental Application (Biogen Inc.)
FDA approved Biogen's supplemental application for TYSABRI (natalizumab), leading to labeling changes under a supplemental submission. The d…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease [Phase 4]
Phase 4 clinical trial update reporting identification of predictive biomarkers for response to biologic therapies and tofacitinib in inflam…