Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-23Clinical Trial Results: An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease [Phase 2, Phase 3]
A randomized active and placebo-controlled study of brazikumab in moderately to severely active Crohn's disease was terminated; results have…
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CLINICAL_TRIALS trial_result · 2026-06-22Clinical Trial Results: Rifaximin in Patients With Diabetic Gastroparesis [Phase 2]
Phase 2 trial results for rifaximin in diabetic gastroparesis are reported (terminated; results posted).
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EMA approval · 2026-06-15EMA Authorised: Entyvio (vedolizumab) — Takeda Pharma A/S
EMA authorises Entyvio (vedolizumab) for use in ulcerative colitis and Crohn's disease with Takeda as MAH.
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EMA approval · 2026-06-09EMA Authorised: Rinvoq (upadacitinib) — AbbVie Deutschland GmbH & Co. KG
EU authorization of Rinvoq (upadacitinib) by AbbVie Deutschland for multiple inflammatory indications including rheumatoid arthritis, psoria…
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EMA approval · 2026-06-05EMA Authorised: Idacio (adalimumab) — Fresenius Kabi Deutschland GmbH
The EMA has authorised Idacio (adalimumab) by Fresenius Kabi Deutschland GmbH for multiple inflammatory diseases, marking a new approved pro…
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Update: Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients [Phase 3]
Phase 3 clinical trial update evaluating guselkumab for Crohn's disease, focusing on transmural healing and potential disease-modifying effe…
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Update: A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease [Phase 3]
Phase 3 trial updating the study of guselkumab in participants with fistulizing perianal Crohn's disease; status is active not recruiting.
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Update: A Long-term Extension Study of Ustekinumab in Pediatric Participants [Phase 3]
Long-term extension study of ustekinumab in pediatric participants (Phase 3) for Crohn disease, ulcerative colitis, and related psoriatic ar…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease [Phase 3]
Phase 3 induction study investigating the efficacy and safety of Duvakitug in moderately to severely active Crohn's disease is currently rec…
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EMA approval · 2026-04-24EMA Authorised: Stelara (ustekinumab) — Janssen-Cilag International NV
The EMA has authorised Stelara (ustekinumab) in the EU for psoriasis, psoriatic arthritis, Crohn's disease and ulcerative colitis.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Interleukin-23 Monoclonal Antibody for Inflammatory Bowel Disease: Efficacy and Safety [Phase 4]
Phase 4 trial evaluating efficacy and safety of an interleukin-23 monoclonal antibody for inflammatory bowel disease is currently recruiting…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
This clinical trial update notes ongoing Seattle Children's Hospital research evaluating spatial transcriptomics in inflammatory bowel disea…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008) [Phase 3]
A Phase 3 clinical trial is evaluating the efficacy and safety of Tulisokibart (MK-7240) in adults with moderate to severe Crohn's disease, …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab [Phase 1, Phase 2]
An open-label Phase 1/2 study evaluating vorinostat for moderate-to-severe Crohn's disease with ustekinumab maintenance therapy; the trial i…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Ileal Crohn's Disease and Post-operative Outcome: Prospective Cohort Study of the REMIND Group [NA]
A prospective cohort study on ileal Crohn's disease and postoperative outcomes led by the REMIND Group is currently recruiting at Saint-Loui…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Implementing a Multimodal RCT Intervention to Improve the Transition of Patients With Crohn's Disease From Pediatric to Adult Care [NA]
This clinical trial update describes a multimodal randomized controlled trial to improve the transition of patients with Crohn's disease fro…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Predictors of Prognosis in IBD Patients
A clinical trial is investigating predictors of prognosis in patients with inflammatory bowel diseases, including ulcerative colitis and Cro…
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EMA approval · 2026-04-23EMA Authorised: Remsima (infliximab) — Celltrion Healthcare Hungary Kft.
EMA authorised Remsima (infliximab) from Celltrion Healthcare Hungary Kft. for multiple inflammatory diseases including rheumatoid arthritis…
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EMA approval · 2026-04-23EMA Authorised: Amgevita (adalimumab) — Amgen Europe B.V.
EMA has authorised Amgevita (adalimumab) by Amgen Europe B.V., a biosimilar of adalimumab, for multiple inflammatory diseases including rheu…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: AI-Enhanced Wide-Field Endoscopic Fluorescence Mapping of Gastrointestinal Mucosal Permeability in IBD - A Pilot Study in IBD Patients and Controls
This pilot clinical trial examines AI-enhanced wide-field endoscopic fluorescence mapping to evaluate gastrointestinal mucosal permeability …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: The Effect of VSL#3 Probiotic Preparation on the Bile Acid Metabolism in Patients With Inflammatory Bowel Disease [NA]
A clinical trial is evaluating the effect of the probiotic preparation VSL#3 on bile acid metabolism in patients with inflammatory bowel dis…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: HB-adMSCs for the Treatment of Crohn's Disease [Phase 2]
Phase 2 clinical trial update for HB-adMSCs in Crohn's disease; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal Response [Phase 4]
A Phase 4 clinical trial is evaluating whether adding low-dose upadacitinib to a TNF inhibitor improves response in Crohn's disease patients…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: BCMA-CD19 cCAR T for the Treatment of Refractory Inflammatory Bowel Disease (IBD) [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describes BCMA-CD19 cCAR T therapy for refractory inflammatory bowel disease, with trial status NOT_YET_RE…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting [Phase 4]
Phase 4 clinical trial update for Vedolizumab in adults with Ulcerative colitis or Crohn's disease in the community setting; the study is cu…