Crohn Disease
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Sign up freeTop drugs studied for this disease
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EMA withdrawal · 2019-03-06EMA Withdrawn: Cyltezo (adalimumab) — Boehringer Ingelheim International GmbH
The EMA withdrew Cyltezo (adalimumab) from Boehringer Ingelheim International GmbH, affecting multiple indications including hidradenitis su…
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EMA withdrawal · 2019-03-05EMA Withdrawn: Solymbic (adalimumab) — Amgen Europe B.V.
Solymbic (adalimumab) has been withdrawn from the market by Amgen Europe B.V.
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CLINICAL_TRIALS withdrawal · 2018-05-14Clinical Trial Update: Effectiveness of Vedolizumab in CD Patients Naïve to Anti-TNF [Phase 4]
A Phase 4 trial evaluating Vedolizumab in Crohn's disease patients naive to anti-TNF therapy has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-11-14Clinical Trial Update: A Study of Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Adult and Adolescent Subjects With Active Crohn's Disease [Phase 3]
The Phase 3 study of Mongersen (GED-0301) for active Crohn's disease has been withdrawn by the sponsor Celgene.
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CLINICAL_TRIALS withdrawal · 2017-07-06Clinical Trial Update: Phase 1 Crohn's Pediatric Sub-study of MSC AFP [Phase 1]
Phase 1 Crohn's disease pediatric sub-study of MSC AFP for perianal fistula has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-05-24Clinical Trial Update: Calprotectin-Directed Humira® Maintenance Therapy (CADHUM) [Phase 3]
A Phase 3 trial evaluating calprotectin-directed maintenance therapy with Humira (adalimumab) for Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-02-03Clinical Trial Update: Autologous Stem Cell Transplant for Refractory Crohn's Disease [Phase 2]
A Phase 2 trial of autologous stem cell transplantation for refractory Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-09-23Clinical Trial Update: Vedolizumab Subcutaneous (SC) Versus Intravenous (IV) in Ulcerative Colitis or Crohn's Disease [Phase 2]
Phase 2 trial comparing subcutaneous versus intravenous vedolizumab in ulcerative colitis and Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-09-16Clinical Trial Update: Effectiveness and Safety of Spondylitis Related to Inflammatory Bowel Disease [Phase 4]
Phase 4 trial evaluating the effectiveness and safety of treatments for spondyloarthritis related to inflammatory bowel disease has been wit…
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CLINICAL_TRIALS withdrawal · 2016-06-16Clinical Trial Update: Study of Tysabri (Natalizumab) in Patients Who Failed Anti-TNF-α Therapy [Phase 4]
A Phase 4 study of Natalizumab (Tysabri) for Crohn's disease in patients who failed anti-TNF-α therapy has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-04-15Clinical Trial Update: Autologous Hematopoietic Stem Cell Transplantation for Crohn's Disease Treatment [EARLY_Phase 1]
An early-phase (Phase 1) trial evaluating autologous hematopoietic stem cell transplantation for Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-04-05Clinical Trial Update: A Crohn's Disease Diet to Reduce Symptoms of Crohn's Disease [NA]
A Johns Hopkins University-sponsored clinical trial investigating a Crohn's disease diet to reduce symptoms has been withdrawn from Clinical…
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CLINICAL_TRIALS withdrawal · 2015-12-03Clinical Trial Update: Improving Treatment of Inflammatory Bowel Diseases Through Better Understanding Infliximab Drug and Antibody Levels
A clinical trial investigating infliximab levels and anti-drug antibodies in Crohn's disease and ulcerative colitis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-11-05Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of 3 Subcutaneous and 1 Intravenous Dose of E6011 in Subjects With Active Crohn's Disease [Phase 1]
A Phase 1 study evaluating E6011 in active Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-09-22Clinical Trial Update: Development of Workshop for Lifestyle Changing for Crohn's Disease Patients and Its Affect on the Disease's Indexes [NA]
A clinical trial for a lifestyle-changing workshop for Crohn's disease patients was withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-09-18Clinical Trial Update: Wireless Capsule Endoscopy in Small-Bowel Crohn's Disease [Phase 1, Phase 2]
A wireless capsule endoscopy trial in small-bowel Crohn's disease (Phase 1/Phase 2) has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-08-24Clinical Trial Update: Genetic Markers as Predictors of Phenotypes in Pediatric Onset Crohn's Disease
The trial evaluating genetic markers as predictors of Crohn's disease phenotypes in pediatric-onset cases has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-06-15Clinical Trial Update: Contrast-Enhanced Ultrasound in Human Crohn's Disease [Phase 1, Phase 2]
A Phase 1/2 trial evaluating contrast-enhanced ultrasound for Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-06-08Clinical Trial Update: Adjuvant Vitamin D With Corticosteroids in Active Crohn's Disease [Phase 4]
A Phase 4 trial evaluating adjuvant vitamin D with corticosteroids for active Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-06-02Clinical Trial Update: Study of Participants With Crohn's Disease and Ulcerative Colitis in Eastern Europe, Middle East, and North Africa (P08166)
A clinical trial (P08166) sponsored by Merck Sharp & Dohme LLC for Crohn's disease and ulcerative colitis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-04-13Clinical Trial Update: Growth Hormone and Exclusion Diet Therapy in Juvenile Crohn's Disease [Phase 2]
A Phase 2 trial evaluating growth hormone plus an exclusion diet for juvenile Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2014-11-20Clinical Trial Update: Low Dose Naltrexone in Symptomatic Inflammatory Bowel Disease [Phase 2]
A Phase 2 trial of low-dose naltrexone for inflammatory bowel disease has been withdrawn. The conditions involved include Crohn's disease an…
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CLINICAL_TRIALS withdrawal · 2014-01-17Clinical Trial Update: L-carnitine to Treat Fatigue Associated With Crohn's Disease [NA]
The clinical trial evaluating L-carnitine for fatigue associated with Crohn's disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2013-10-18Clinical Trial Update: Investigation of Sexual Function in Crohn's Disease Patients With Perianal Fistulas
The clinical trial investigating sexual function in Crohn's disease patients with perianal fistulas has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2013-03-07Clinical Trial Update: Open Label Extension Study to Protocol C2/13/DR-6MP-02 [Phase 2]
A Phase 2 open-label extension study (Protocol C2/13/DR-6MP-02) for Crohn's disease has been withdrawn.