Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Transcutaneous VNS to Treat Pediatric IBD [NA]
A completed clinical trial evaluating transcutaneous vagus nerve stimulation for pediatric inflammatory bowel disease. The study included ch…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative Colitis [Phase 2]
Phase 2 trial update evaluating the long-term safety and efficacy of deucravacitinib in participants with Crohn's disease or ulcerative coli…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD) [Phase 3]
This Phase 3 trial evaluated Cx601 (darvadstrocel), an allogeneic adipose-derived stem cell therapy, for complex perianal fistulas in Crohn'…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: ENhanced Recovery in CHildren Undergoing Surgery [Phase 3]
A Phase 3 clinical trial assessing Enhanced Recovery in children undergoing surgery for inflammatory bowel disease has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Correlation Between RISANKIZUMAB's Trough Levels, Clinical and Biological Remission in Moderate to Severe Crohn's Disease: a Retrospective Multicentric Study
A retrospective multicenter study evaluating the relationship between risankizumab trough levels and clinical/biological remission in adults…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Digital Behavioral Interventions in Inflammatory Bowel Disease [NA]
A completed clinical trial conducted at Montefiore Medical Center evaluated digital behavioral interventions for patients with Crohn's disea…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) [Phase 1]
A Phase 1 clinical trial evaluating certolizumab pegol (Cimzia) in pregnant women with chronic inflammatory diseases has completed and poste…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Dietary Intervention Study on the Microbiome in Crohn's Disease Patients [NA]
This ClinicalTrials.gov update reports the completion of a dietary intervention study examining the gut microbiome in Crohn's disease patien…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: FAPi-PET Imaging of in Vivo Fibrosis in Inflammatory Bowel Disease Patients [Phase 2]
Phase 2 clinical trial evaluating FAPi-PET imaging of in vivo fibrosis in inflammatory bowel disease patients is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: IUS Predicts Upadacitinib Efficacy in Patients With Moderate to Severe Crohn's Disease：a Prospective Study
A prospective study suggests intestinal ultrasound predictors may forecast the efficacy of upadacitinib in patients with moderate-to-severe …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Mesentery Guide Identify Microscopic Clean Resection and Reduces Crohn's Endoscopic Recurrence
A completed clinical trial evaluating a mesentery-guided surgical approach for Crohn's disease reported achieving microscopic clean resectio…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: A Study on How Vedolizumab is Given and the Outcomes for Adults With Inflammatory Bowel Disease (VARIETY-Belgium)
A completed study assessing how vedolizumab is administered and the outcomes in adults with inflammatory bowel disease (VARIETY-Belgium).
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: A Study of the Quality of Life in Adults With Crohn's Disease With Complex Perianal Fistulas
The study on quality of life in adults with Crohn disease and complex rectal fistulas has completed and posted its results.
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Pharmacokinetics, Efficacy and Safety of CT-P13 Subcutaneous as Induction Therapy in Patients With Active CD or UC [Phase 3]
Phase 3 clinical trial evaluating pharmacokinetics, efficacy and safety of subcutaneous CT-P13 as induction therapy in adults with active Cr…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: A Study of Vedolizumab in Adults in Real-World Practice
This real-world study of Vedolizumab in adults with ulcerative colitis or Crohn's disease has completed. It evaluated treatment outcomes in …
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Adalimumab Trough Concentrations in Crohn's Disease: A Pilot Pharmacokinetic Study
A completed pilot pharmacokinetic study evaluated adalimumab trough concentrations in Crohn's disease to characterize drug exposure.
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease [Phase 3]
A Phase 3 long-term extension study of filgotinib in adults with Crohn's disease has been terminated, and the results have been posted.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's Disease [Phase 2]
A Phase 2 trial of BMS-986165 in moderate-to-severe Crohn's disease was terminated, and results have been posted. The update provides the as…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: The Innate Immune Response and Enteric Nervous System in Crohn's Disease.
A Crohn's disease clinical trial studying the innate immune response and enteric nervous system was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: A Study to Evaluate the Effect of Intravenous (IV) Infusions of Risankizumab on Pharmacokinetics of Cytochome P450 Substrates in Adult Participants With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease [Phase 1]
A Phase 1 study assessing whether intravenous risankizumab alters the pharmacokinetics of cytochrome P450 substrates in adults with moderate…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Home basEd faecaL calProtectin Measurements Predicting Adalimumab Induction Destiny [NA]
A completed KU Leuven study evaluated whether home-based fecal calprotectin measurements can predict the induction outcome of adalimumab in …
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Significance and Outcome of Magnetic Resonance Enterography Revealing Sacroiliitis in Crohn's Disease: A Pilot Study [NA]
A completed pilot study evaluating the significance and outcomes of magnetic resonance enterography-detected sacroiliitis in Crohn's disease…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: A Safety Extension Study of Ontamalimab in Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease (AIDA) [Phase 3]
Safety extension results from a Phase 3 trial of ontamalimab in moderate to severe Crohn's disease or ulcerative colitis have been completed…
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: Comparative Effectiveness of Biologics or Small Molecule Therapies in Inflammatory Bowel Disease (IBD)
Completed comparative effectiveness trial comparing biologics and small-molecule therapies for Crohn's disease and ulcerative colitis, with …
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Comparison of Trough Level- and Clinical-based Spacing of Infliximab Infusions in Patients With IBD in Deep Remission [NA]
This update reports a terminated clinical trial comparing trough-level–based spacing to clinically based spacing of infliximab infusions in …